Sentences with phrase «cellular pathways activate»

March 13, 2017 Parallel cellular pathways activate the process that controls organ growth A new study from the University of Chicago suggests that while proteins that control organ growth accumulate around the edges of cells, they actually function at a different cellular site.

Not exact matches

G protein - coupled receptors (GPCRs) are actually a huge protein family (i.e., superfamily) of transmembrane receptors that sense molecules outside Eukaryotic Cells in species ranging from yeast to humans, and activate very basic biological pathways and cellular responses inside the cells.

In this new paper, the researchers reveal more about that mechanism, showing that without the protective ability of BRCA1, breaks in the DNA strands go unfixed, prompting the molecule ATM kinase to activate a cellular «suicide» pathway involving a protein called p53.

The damage that it will repair is the one that is causal in senenscence of DNA pathway (such x-ray radiation causing senescence) and oncogenic activated senescence; but not of the type of replicative senescence (that's the domain of telomeres / telomerase / sub-telomeres and epigenetics) and cellular replication / proliferation.

The model will describe cellular pathways that contribute to tumor formation and explain in detail how the genetic disposition of an individual can activate expression of genes that drive uncontrolled cell growth and lead to cancer.

This understanding of the cellular and molecular mechanism of recovery from acute promyelocytic leukaemia opens prospects for activating this same PML / p53 pathway in other types of cancers.

Insulin is not needed for protein synthesis or to activate the mTOR pathway, that causes cellular growth.

Reactive oxygen species trigger cellular responses by activation of stress - responsive mitogen - activated protein kinase (MAPK) signalling pathways.