Sentences with phrase «cellular processes such»

Such work yields unique mechanistic insight by directly illustrating the complex spatial - temporal dynamics of fundamental cellular processes such as mitosis, morphogenesis, polarization, embryonic development, membrane trafficking and cytoskeleton dynamics.

Moreover, the data can serve as a basis for studies concerning the evolution of signaling mechanisms, as well as can give specific insights into the regulation of basic cellular processes such as polar cell growth, cell expansion, plant morphogenesis and the plants responses to fungal pathogens.

Others were unanticipated, including significant differences in expression levels among genes involved in fundamental cellular processes such as ribosomal biogenesis, transfer RNA processing, and Notch - signaling — part of a complex system of communication that governs basic cellular activities and coordinates cell actions.

Consequently, many cellular processes such as endocytosis, migration and morphogenesis rely on proteins that bind directly to membranes and sculpt them into desired shapes.

Made of polymers in dynamic assembly and constantly constructing and deconstructing itself, it affects numerous cellular processes such as intracellular movement, division and transport.

We can use the larger number of 2 - D images to derive semi-3-D information about cellular processes such as division and organelle formation.»

Interest in studying tRNA fragments has been increasing swiftly as studies have shown that the fragments have regulatory roles and implicated individual fragments in cellular processes such as translation initiation, response to viral infection, response to DNA damage, etc..

Not exact matches

Just as quantum mechanics is needed to, and does perfectly, fill the gap between the atomic structure of crystals and their beautiful shape in space, so too it will be needed to link the biochemistry of genetic code and cellular processes to the growth and shape of living things — provided, that is, that such a link can be found at all.

A host of other genes, which control many other cellular processes do not show such abnormal DNA methylation after smoke exposure.

Izpisua Belmonte added that more extensive studies will be needed to fully understand the role of heterochromatin disorganization in aging, including how it interacts with other cellular processes implicated in aging, such as shortening of the end of chromosomes, known as telomeres.

However, because the enzyme was involved in so many critical cellular processes, the researchers knew that such an approach would yield nothing more than dead fruit flies.

At Actelion, employees are increasingly motivated by visualization technologies, such as automated live - cell imaging and high content screening, that offer new means to view and quantify cellular, even subcellular, processes.

Proteins called kinesins, for example, are natural nanomotors that support cellular functions such as mitosis (the chromosomal process that creates two nuclei from one parent nucleus) and meiosis (when the number of chromosomes per cell is reduced by one half).

Normally, cytokinesis is such a fundamental cellular process that it proceeds virtually identically in all cells; but here something very odd was happening.»

In spite of this sizable gap, certain vitally important processes such as memory formation use similar cellular mechanisms in humans, mice and flies, as the researchers» experiments were able to prove.

Such experiments suggest that deletion of cellular activity, even for a brief time, «is causally involved with a pathological process like narcolepsy,» Boyden said.

The detailed study of such fundamental cellular processes is crucial for the understanding of diseases that go hand in hand with these events — in the case of autophagy, Alzheimer's disease or cancer.

«This camera has the potential to greatly enhance our understanding of very fast biological interactions and chemical processes that will allow us to build better models of complex, dynamical systems such as cellular respiration, or to help doctors better deliver and monitor light - based therapies,» says Richard Conroy, Ph.D., program director for Optical Imaging at NIBIB.

Mutations can be caused by copying errors in the genetic material during cell division and by exposure to radiation, chemicals, or viruses, or can occur deliberately under cellular control during the processes such as meiosis or hypermutation.

Knowing how cells exert force and sense mechanical feedback in their microenvironment is crucial to understanding how they activate a wide range of cellular functions, such as cell reproduction, differentiation and adhesion — basic physiological processes that underlie embryo development, tumor metastasis, wound healing and many other aspects of human health and disease.

Traditional hydrogels made up of either synthetic polymers or natural biomolecules often serve as passive scaffolds for molecular or cellular species, which render these materials unable to fully recapitulate the dynamic signaling involved in biological processes, such as cell / tissue development.

LA JOLLA — A study tying the aging process to the deterioration of tightly packaged bundles of cellular DNA could lead to methods of preventing and treating age - related diseases such as cancer, diabetes and Alzheimer's disease, as detailed April 30, 2015, in Science.

The consistent segregation of these regions, in the same way in every cell, suggests that these processes could drive chromosome and genome folding and thus regulate important cellular events such as DNA replication and cell division.

Antibiotics stop or interfere with a number of everyday cellular processes that bacteria rely on for growth and survival, such as:

From a functional perspective, «interaction» can mean anything from direct physical binding to indirect functional association such as participation in the same metabolic pathway or cellular process.

This includes cellular mechanisms such as photosynthesis and transpiration, and how plant processes are affected by environmental factors or natural variations.

Our ultimate goals in this activity include (1) a better understanding of the molecular mechanisms governing cellular processes and especially those involved in certain kinds of diseases such as cancer and (2) the development of computational tools that can be used for diagnostic / prognostic purposes based on genomic data.

(9) Indeed, the degenerative aging process is by definition one in which the organism progressively accumulates damage to its cellular and molecular components over time, so any genetic or environmental factor that leads to a greater burden of such damage will bear some resemblance to the aging phenotype, irrespective of the causal origin of the defect or its relationship to «normal» aging.

One of the ten emerging technologies selected was the Human Cell Atlas, which aims to integrate research exploring all the «omes»: the genome (the full set of genes), the transcriptome (the RNA made from all genes), the proteome (the proteins), the metabolome (small molecules, such as sugars, fatty acids and amino acids, involved or generated by cellular processes), and the fluxome (metabolic reactions whose rates can vary under different conditions).

Autophagy (more specifically macroautophagy) is the process by which cellular compartments, such as membranes and organelles and also protein aggregates, are recycled back into their building blocks [122].

LA JOLLA — A study tying the aging process to the deterioration of tightly packaged bundles of cellular DNA could lead to methods of preventing and treating age - related diseases such as cancer,...

Sphingolipid metabolites, such as ceramide, sphingosine, and sphingosine -1-phospate are lipid signaling molecules which are involved in diverse cellular processes.

Chromatin dynamics have proved crucial to such fundamental cellular processes as cell division, DNA repair and protein production.

Enhanced amyloidogenic processing of APP by the ß - site APP cleaving enzyme (BACE) and the γ - secretase complex and reduced clearance lead to increased intracellular levels of soluble oligomeric Aß, resulting in cellular dysfunction comprising e.g., synaptic failure, mitochondrial dysfunction, enhanced oxidative stress, neurotransmitter and neurotrophin depletion, inflammation, and apoptosis which is reflected in patients as clinical symptoms such as cognitive deficits [2, 3].

These anti-aging products also include antioxidant rich formulas that address aging on a cellular level for a wide range of aging processes and support functions such as joint, cognitive, and skin health.

Generation of reactive oxygen species, or free radicals such as superoxide and hydrogen peroxide, is a normal byproduct of metabolism, but can damage cellular machinery when excessive and impair the production of cellular energy, which becomes a vicious cycle as energy - intensive repair processes become untenable (25, 26).

Such effects may occur through a process of «neurohormesis» in which cellular components of the CNS respond to exogenous and endogenous toxic agents (e.g. - H2S, NO, CO, glutamate, calcium) that act as mild stressors to facilitate neuronal resistance against stronger insults.»

Mercury is a potent cellular toxin and is known to decrease neurotransmitter production, disrupt important processes within the nerve cells, and decrease important hormones such as thyroid and testosterone.

Additionally, more than half of the participants implemented inquiry instruction with the IDS, most often through the use of online simulations that allowed students to manipulate variables, test predictions, and «see» phenomena (such as cellular processes) that would otherwise be impossible to observe.

Bitumen (1986) is a work from the first decade of his career, when Winters was exploring such basic natural processes as crystal formation, fungal growth, and (as in this oil on linen painting) cellular division and was equally immersed in the natural history of painting itself.