Sentences with phrase «cellular proliferation»

Cellular proliferation refers to the process of cells multiplying and increasing in number. It is like a rapid growth of cells, where they divide and reproduce. This growth is a normal part of life, allowing our bodies to develop, heal, and replace old or damaged cells. However, uncontrolled cellular proliferation can lead to serious health issues, such as cancer, where cells divide too rapidly and form tumors. Full definition
The gene plays a key role in cellular proliferation and is activated in 90 % of all human pancreatic tumors.
This makes sense: By driving the proliferation of infected cells, viruses speed manufacture of more viruses, but excessive cellular proliferation is also a hallmark of cancer.
In a previous study melan - A cells, showed increased cellular proliferation upon introduction of exogenous mutated BRAF (V600E), however no tumor formed [43].
Since these proteins are involved in negatively regulating cell division, this supports previous findings that there is increased potential for cellular proliferation in the peripheral rather than in the central cornea (unpublished and [5]-RRB-.
While cancer is extraordinarily complex at the molecular level, at the cellular level there is a universal theme - uncontrolled cellular proliferation.
The laboratory of Marcos Malumbres, who is head of the Spanish National Cancer Research Centre's (CNIO) Cell Division & Cancer Group, working alongside Isabel Fariñas» team from the University of Valencia, shows, in a study published today in the journal Nature Communications, how in mice the elimination of the Cdh1 protein — a sub-unit of the APC / C complex, involved in the control of cell division — prevents cellular proliferation of rapidly dividing cells.
«Molecular mechanism involved in cellular proliferation characterized
This combination inhibits cellular proliferation, cell survival and pathways involved in metastasis.
Notch signaling coordinates cellular proliferation with differentiation during zebrafish fin regeneration.
Metazoans can now be defined by a long list of genomic synapomorphies — gene content, intron — exon structure and syntenies — as well as characteristics common to all animal life such as sex, development, controlled cellular proliferation, differentiation and growth, and immunity.
- Synthesis of specific inhibitors of beta - catenin The progressive accumulation of nuclear beta - catenin, which deregulates cellular proliferation, differentiation, and migration, is an initial event in the development of colonic tumorigenes.
The principal function of the estrogens is to cause cellular proliferation and growth of the tissues of the sexual organs and tissues related to reproduction.
This peptide hormone has a molecular structure very similar to insulin and it regulates cellular proliferation.
Naturally derived Alpha and Beta Hydroxy acids penetrate deeper in to the epidermal layer to treat problematic, pigmented, aging, and dry skin, while promoting cellular proliferation.
Regulation of cellular proliferation, cytoskeletal function, and signal transduction through CXCR4 and c - Kit in small cell lung cancer cells.
«Our next target is to extend cell viability time and to find a more efficient culture method for cellular proliferation
Cancerisation can result from perturbations at each of these levels and is linked to misregulation of developmental signalling pathways, uncontrolled cellular proliferation and a loss of cellular identity.
As described in the article, when NANOG was increased in these mice, the epithelia showed an increase in cellular proliferation, hyperplasia, and an increase in the amount of DNA damage in the cells.
The PI3K / AKT pathway is a suspect, and its well - known links to cellular proliferation and survival may be connected to mediating the change at the cellular level.
What makes this technique novel is the accompaniment of an imaging agent known as Ga - 68 DOTATOC, which binds to somatostatin receptors in neuroendocrine cells that use the hormone somatostatin to mediate endocrine function, the release of neurotransmitters and cellular proliferation.
Rho - kinase inhibitor treatment increased the cellular proliferation up to twofold during the first 12 h, and a wound model based migration assay showed 50 % faster filling of the mechanically generated wound area.
Rho - kinase inhibitor Y - 27632 increases cellular proliferation and migration in human foreskin fibroblast cells
He studies the molecular mechanisms by which female steroid hormones such as estrogen control development, differentiation, cellular proliferation and survival in hormone - responsive tissues and cancers.
Because sorafenib inhibits the chemical signals that can trigger both cellular proliferation and new blood vessel growth, Gomberg - Maitland and colleagues suspected it might slow the growth and thickening of the pulmonary artery walls.
Sphingosine -1-phosphate is a potent signaling lipid involved in numerous biological functions including, cellular proliferation, survival, migration, invasion, differentiation, architecture, immune cell trafficking, angiogenesis and vascular integrity.
Studies on the effects of GHRH antagonists on prostate and lung cancers demonstrated their ability to modulate signaling pathways involved in cellular proliferation, survival, metastasis, and apoptosis.
[6, 30, 54] Evaluations of GHRH antagonists in prostate and lung cancers demonstrated their ability to modulate signaling pathways involved in cellular proliferation, survival, metastasis, and apoptosis.
Significant drop in PSA levels (which is a biomarker of prostate cell growth); a drop in cholesterol (which is what we'd expect with a lower - fat diet, and all that extra fiber); and, importantly, a significant decrease in the cellular proliferation rate.
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