This is because the tumors in mice mirror the genetics as well as the molecular and
cellular properties of tumors in humans.
Specifically, maternally - inherited DNA methylation marks are important for normal placentation as they
specify cellular properties such as adhesiveness and invasive character, as well as determining the correct balance of cell types needed in the placenta.»
The ability to obtain neurons directly and non-invasively from human individuals of different age groups will offer opportunities to study
intrinsic cellular properties... >> MORE
Applying these paradigms on various neural differentiation schemes of human pluripotent stem cells allows us to identify and isolate new types of neural stem and progenitor cells, to characterize
their cellular properties and molecular foundations, to expose their progenitor origin and track their imminent potential, to reveal their in vivo counterparts and learn about their regenerative potential.
Sphingosine kinase 2 (SK2) is an enzyme that synthesizes a fat - like molecule that regulates a variety of
cellular properties.