Sentences with phrase «cellular properties of»

This is because the tumors in mice mirror the genetics as well as the molecular and cellular properties of tumors in humans.

Not exact matches

That's because these mobile apps were specifically designed to take advantage of the smartphone with all of its unique properties, such as a touch screen and ability to connect to the Internet via cellular networks.

say, the atomic level do not begin to predict the properties of matter at the cellular level, let alone at the level of complex organisms.

It was commissioned by Roderick MacKinnon, who shared the Nobel prize in 2003 for his work describing the structural and mechanistic properties of such channels, which are tunnels that regulate the flow of ions across cellular membranes.

The objective of the research project led by Marko Kallio, Principal Scientist at VTT, was to accelerate the drug development process by identifying new compounds that would possess similar binding properties and cellular phenotype, but a different chemical structure, as the selected drugs in clinical use or investigational compounds in development.

These data demonstrate that in RNA's with very different cellular functions, there are domains with similar structural and functional properties and that there is a nucleotide in M1 RNA that affects the site of cleavage by the enzyme.

Valproic acid is widely used to treat various types of seizure disorders, but to this point, the cellular mechanism affected by its anticonvulsant properties were not well understood.

Rapamycin, which is an inhibitor of the mammalian target of rapamycin (mTOR) signaling pathway, has a variety of cellular functions and is known to possess both immunosuppressant and anti-tumor properties.

They also plan to evolve the chemistry behind the materials so that it may be possible for gels to better mimic more complex cellular environments beyond the control of stiffness alone, as well as investigate how dynamic changes in matrix properties — a hallmark of the stem cell niche — can be mimicked in the laboratory.

Dr. Monteggia's lab focuses on the molecular and cellular bases of neural plasticity, the fundamental property of nerve cells to alter their communication, as they pertains to neuropsychiatric disorders, as well as understanding the mechanisms underlying antidepressant efficacy.

«We found that mitochondria communicate changes in cellular organization to initiate a specific metabolic reconfiguration that supports primitive hMSC properties,» said Dr. Teng Ma, senior author of the STEM CELLS study..

Rapamycin is an antifungal metabolite of the Streptomyces hygroscopicus bacterium and among its many properties is the ability to induce autophagy — the regulated, orderly degradation and recycling of cellular components.

This Purkinje neuron was derived from patients with tuberous sclerosis and model properties of the disease at the cellular and molecular level.

Specifically, maternally - inherited DNA methylation marks are important for normal placentation as they specify cellular properties such as adhesiveness and invasive character, as well as determining the correct balance of cell types needed in the placenta.»

The mechanical properties of biological systems play a major role in cellular processes.

Amy Gladfelter's «Companions in Discovery» follows her lab's investigations into the physical properties of cellular proteins by using the fungus, Ashbya, as a lab model.

DA - HCS offers a variety of coatings for different cellular applications, optical properties compatible for imaging, and both 96 - and 384 - well formats

Stem cells — the body's master cells — demonstrate a bizarre property never before seen at a cellular level, according to a study published today from scientists at the University of Cambridge.

Text mining of cellular, synaptic, connectomic or functional properties of the brain

Asterias maintains an extensive global intellectual property portfolio including broad issued claims to fundamental platform technologies including, but not limited to, scalable growth of pluripotent stem cells, methods of production and compositions of matter for several hESC - derived therapeutic cell types, and cellular immunotherapy using the telomerase antigen.

To this end, we design new multi-scale quantitative methods that can resolve the local dynamics of soluble proteins, dissect the architecture of cellular structures, and characterize the mechanical properties and dynamics at large scales.

Finally, in a collaboration with Frank Jülicher's group at the Max Planck Institute for the Physics of Complex Systems, we are using these data to develop physical models that will help us understand how local cellular adhesive, elastic and contractile properties are influenced by PCP proteins and other molecules, and how they combine to produce specific packing geometries at a global level.

Stem cells are characterized by their ability to both reproduce themselves and to differentiate into functional tissues, foundational properties that enable their use as the starting material for manufacture of cellular therapeutics to address complex disease.

The ability to obtain neurons directly and non-invasively from human individuals of different age groups will offer opportunities to study intrinsic cellular properties... >> MORE

Applying these paradigms on various neural differentiation schemes of human pluripotent stem cells allows us to identify and isolate new types of neural stem and progenitor cells, to characterize their cellular properties and molecular foundations, to expose their progenitor origin and track their imminent potential, to reveal their in vivo counterparts and learn about their regenerative potential.

This property will enable the use of UNC0638 without concern about possible complications of cellular toxicity.

According to a release from Dr. Hassan Dihazi, editor in chief, the journal covers all areas of proteomics including basic proteomic research; structural, functional, property, and interaction analysis of cellular systems, organelles, and protein complexes; and protein expression profiling for the discovery and validation of diagnostic and prognostic disease biomarkers.

Therefore the group studies with sophisticated imaging technology in vitro and ex vivo: i) the molecular mechanism driving the migration of HIV through the intestinal epithelial barrier; ii) the cellular targets in the mucosa, in specific macrophages and DCs, to identify the possible pathways to invade the tissue and disseminate to other organs; iii) the involvement of DCs and their functional properties in mediating adaptive immune responses at mucosal level; and iv) the role of antibodies with different effector functions in changing the pathways of the virus.

Important features of XMRV biology include (1) tropism for a variety of cell lines, including prostate cancer DU145 and LNCaP cells [27], [43], [48], and human neural cell types [57], (2) adaptations that promote growth in prostate epithelium and human - derived prostate cancer cell lines including an androgen response element in the promoter region [58] and downregulation of APOBEC3G [59], and (3) cellular effects with potential oncogenic properties including increased tumor aggressiveness mediated by downregulation of p27 [60] and differential regulation of several microRNAs [61].

This result, together with the tunable and multifunctional properties of PNBs in vitro and in vivo [34,40,50] that support diagnosis, therapy and theranostics (diagnosis and treatment united in one procedure) at the cellular level and with single cell selectivity, justify the development of PNB theranostic technologies despite the general limitations mentioned above.

Sphingosine kinase 2 (SK2) is an enzyme that synthesizes a fat - like molecule that regulates a variety of cellular properties.

Like many antioxidants, catechins have a multitude of healing properties on a cellular level.

Allicin affects RNA synthesis, inhibiting the reproduction of viruses and bacteria, while phenols and quercetin possess antioxidant properties, inhibiting the cellular damage caused by free radicals.

Rhamnazin has also shown protective properties against inflammation in acute lung injury, inhibiting the metabolism of cytokines, which are proteins secreted by the immune system in order to affect cellular functions.

Use Vegan Single Source SBT both internally and externally for its many healing properties; SBT Vegan Single Source supports cellular regeneration as a component of the skin fat and creates a silky soft and smooth feeling.

The antioxidant property of walnuts makes your body free from cellular damage, cancer, heart disease and premature aging.

Not only does urea and urine moisturize and hydrate the skin, it also helps to promote wound - healing, accelerating the process of cellular renewal, and also has some anaesthetic properties, reducing the irritation and burning sensations that often accompany rosacea.

It has strong antioxidant properties that allow it to inhibit the ability of free radical compounds to damage cellular tissue and DNA.

The antioxidant properties of these natural forms of vitamin E fight aging on a cellular level and keep LDL («bad») cholesterol from oxidizing and hardening in your blood vessels and arteries.

Both of these minerals have antioxidant properties and contribute to the reduction of free radicals, which are the source of cellular damage.

The antioxidant properties of selenoproteins help prevent cellular damage from free radicals.

Qualcomm owns multiple intellectual properties for Code Division Multiple Access (CDMA) and Orthogonal Frequency Division Multiple Access (ODFMA)-- both of which are used in cellular wireless communications.

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After lunch we'd crossed onto Arkaba land, and for the rest of the walk we had been alone on the property, further isolated by the lack of cellular communication and electricity.

His doctoral research focused on the structure and function of ion channels, the proteins that mediate cellular electrical properties.

A study of UK law firms by property organisation CBRE found a clear differential between open plan and cellular: 310 sq ft occupied per fee earner in open - plan offices compared to 550 sq ft per fee earner in a cellular model.

Research indicates that over 90 % of home buyers and renters are less interested in properties near cell towers and would pay less for a property in close vicinity to cellular antennas.