Our hypothesis is that the centralized inhibitory control over
the cellular protein quality control mechanisms has evolved to prevent their chronic activation which could be detrimental to metazoan growth and reproduction under normal conditions.
Not exact matches
Its
cellular machinery will execute the program by producing the same
protein as the native organism, taking on new
qualities, just as in recombinant techniques.
«Much work still lies ahead, but we are optimistic that the basic research toward understanding the
cellular machinery of
protein folding and
quality control will eventually contribute to solving some of the most pressing medical problems of our aging population,» Hartl said.
For elucidating the unfolded
protein response, a
cellular quality - control system that detects disease - causing unfolded
proteins and directs cells to take corrective measures.
There is a basal
cellular housekeeping provides
quality control on the
proteins in our body.
Low -
quality protein intake can lead to
cellular stress; low sex drive; poor brain function, eye health and cardiovascular disease.