"Cellular receptors" refers to specific molecules found on the surface of cells that receive signals or messages from various substances in the body. These receptors act like a lock, and when the right substance (key) binds to them, they trigger specific responses or actions within the cell. It's like a communication system that helps cells interact with their environment and perform their functions.
Full definition
It does not matter how much free testosterone is available if excess estrogen is competing for the same
cellular receptor sites.
While current practices of precision medicine target a
single cellular receptor, the new modular platform offers a robust biological approach — and may hold the key to the future of personalized medicine.
Myasthenia gravis is caused by a reduction or deficiency in the number of
cellular receptors for a specific neurotransmitter, acetylcholine, at the junctions between nerve endings and skeletal muscle cells.
Johns Hopkins scientists have used a form of artificial intelligence to create a map that compares types
of cellular receptors, the chemical «antennas» on the surface of immune system T - cells.
These proteins were originally discovered
as cellular receptors for immunosuppressive drugs, including cyclosporin A and FK506.
While these two ligands activate
cellular receptors in the same way, they do so in different patterns over time.
Apr. 18, 2018 — A Vanderbilt team and their international colleagues characterized for the first time a complex, little - understood
cellular receptor type that, when activated, shuts off hunger.
Oddly enough, capsaicin and 6 - gingerol both bind to the
same cellular receptor — one that is related to tumor growth.
This attachment twists gp120 such that it exposes a region on the virus that can attach to the
second cellular receptor, CCR5.
They either activate or
inactivate cellular receptors, cell responses, and other targets and can cause higher insulin resistance and hyperinsulinemia.
What happened is artificially administered testosterone becomes bound by SHBG, and is not bioavailable to
cellular receptor sites where it would normally produce a libido / sexual enhancing effect.
Molecular biologist Elizabeth Wilson of the University of North Carolina in Chapel Hill says that whereas «there are lots and lots of compounds that will activate the estrogen receptor,»
the cellular receptors that respond to androgens are choosy.
In mice (though not in people), the mother counteracts the pro-growth tumult by expressing a gene for
a cellular receptor that regulates the growth hormone's effectiveness.
Earlier this year, they reported the identification of
the cellular receptor that binds the toxin.
Cutler's collaborators on the research project are Brian Volkman and Francis Peterson at the Medical College of Wisconsin, who helped unravel the mechanism by which quinabactin mimics ABA by determining the atomic structure of the new molecule bound to one of
its cellular receptors.
The discovery of
the cellular receptor for HCMV represents a new step toward the control of this highly prevalent human pathogen.
While
the cellular receptors for other rhinovirus types are known, the rhinovirus C receptor had remained elusive.
He notes, for example, his lab's surprising finding that the mutations connected to transmission do not simply involve the way influenza's hemagglutinin protein binds to
cellular receptors, as many researchers assume.
Scientists funded by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, have identified
a cellular receptor for rhinovirus C, a cold - causing virus that is strongly associated with severe asthma attacks.
Researchers pinpoint
the cellular receptor MRGRPX2 as the main mechanism for opioid - induced itching.»
ApoE is activated in part by
a cellular receptor called RXR; bexarotene enhances RXR action.
The authors determined that GDF15 activated a population of nerve cells called AP neurons that make up a portion of the gut - brain axis, yet note that further studies to identify the protein's
cellular receptor are needed as potential therapeutics make their way to the clinic.
To measure and compare concentrations, cells count stochastic binding events of signalling molecules that diffuse to
cellular receptors.
Finkelshtein, D., Werman, A., Novick, D., Barak, S., Rubinstein, M. «LDL receptor and its family members serve as
the cellular receptors for vesicular stomatitis virus.»
After graduating, Clara moved to the UK to work as a Research fellow with Prof John Findlay at the University of Leeds, working mainly with Lipocalins and
their cellular receptors, identifying structural binding / transport motifs and investigating the physiological link between vitamin A uptake and Type 2 Diabetes.
The bacterial Shiga toxin interacts with
its cellular receptor, the glycosphingolipid globotriaosylceramide (Gb3 or CD77), as a first step to entering target cells.
Here, we tested whether human gastric cancers, which are among the most aggressive tumor entities, express
the cellular receptor of Shiga toxin, the glycosphingolipid globotriaosylceramide (Gb3 / CD77).
Insulin is a hormone carrier that transports nutrients and glucose in the blood and binds them to
cellular receptor sites.