Sentences with phrase «cellular receptors»

"Cellular receptors" refers to specific molecules found on the surface of cells that receive signals or messages from various substances in the body. These receptors act like a lock, and when the right substance (key) binds to them, they trigger specific responses or actions within the cell. It's like a communication system that helps cells interact with their environment and perform their functions. Full definition
It does not matter how much free testosterone is available if excess estrogen is competing for the same cellular receptor sites.
While current practices of precision medicine target a single cellular receptor, the new modular platform offers a robust biological approach — and may hold the key to the future of personalized medicine.
These designer antibodies could be used, among other things, to detect and manipulate cellular receptors.
The surface structure and cellular receptors differ among RV species, particularly for RV - C.
Myasthenia gravis is caused by a reduction or deficiency in the number of cellular receptors for a specific neurotransmitter, acetylcholine, at the junctions between nerve endings and skeletal muscle cells.
Johns Hopkins scientists have used a form of artificial intelligence to create a map that compares types of cellular receptors, the chemical «antennas» on the surface of immune system T - cells.
These proteins were originally discovered as cellular receptors for immunosuppressive drugs, including cyclosporin A and FK506.
While these two ligands activate cellular receptors in the same way, they do so in different patterns over time.
Apr. 18, 2018 — A Vanderbilt team and their international colleagues characterized for the first time a complex, little - understood cellular receptor type that, when activated, shuts off hunger.
Many of those efforts have focused on drugs that target cellular receptors in the brain called NMDA receptors.
For example, the use of computer graphics permits cellular receptors to be visualised and the design of molecules to fit them.
Oddly enough, capsaicin and 6 - gingerol both bind to the same cellular receptor — one that is related to tumor growth.
This attachment twists gp120 such that it exposes a region on the virus that can attach to the second cellular receptor, CCR5.
Aptamers are also being selected against specific cellular receptors for use in cancer therapy.
They either activate or inactivate cellular receptors, cell responses, and other targets and can cause higher insulin resistance and hyperinsulinemia.
Toxins can block cellular receptors, or they can destroy healthy thyroid tissue.
What happened is artificially administered testosterone becomes bound by SHBG, and is not bioavailable to cellular receptor sites where it would normally produce a libido / sexual enhancing effect.
Molecular biologist Elizabeth Wilson of the University of North Carolina in Chapel Hill says that whereas «there are lots and lots of compounds that will activate the estrogen receptor,» the cellular receptors that respond to androgens are choosy.
In mice (though not in people), the mother counteracts the pro-growth tumult by expressing a gene for a cellular receptor that regulates the growth hormone's effectiveness.
Earlier this year, they reported the identification of the cellular receptor that binds the toxin.
Cutler's collaborators on the research project are Brian Volkman and Francis Peterson at the Medical College of Wisconsin, who helped unravel the mechanism by which quinabactin mimics ABA by determining the atomic structure of the new molecule bound to one of its cellular receptors.
The discovery of the cellular receptor for HCMV represents a new step toward the control of this highly prevalent human pathogen.
While the cellular receptors for other rhinovirus types are known, the rhinovirus C receptor had remained elusive.
He notes, for example, his lab's surprising finding that the mutations connected to transmission do not simply involve the way influenza's hemagglutinin protein binds to cellular receptors, as many researchers assume.
Scientists funded by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, have identified a cellular receptor for rhinovirus C, a cold - causing virus that is strongly associated with severe asthma attacks.
Researchers pinpoint the cellular receptor MRGRPX2 as the main mechanism for opioid - induced itching.»
ApoE is activated in part by a cellular receptor called RXR; bexarotene enhances RXR action.
The authors determined that GDF15 activated a population of nerve cells called AP neurons that make up a portion of the gut - brain axis, yet note that further studies to identify the protein's cellular receptor are needed as potential therapeutics make their way to the clinic.
To measure and compare concentrations, cells count stochastic binding events of signalling molecules that diffuse to cellular receptors.
Finkelshtein, D., Werman, A., Novick, D., Barak, S., Rubinstein, M. «LDL receptor and its family members serve as the cellular receptors for vesicular stomatitis virus.»
After graduating, Clara moved to the UK to work as a Research fellow with Prof John Findlay at the University of Leeds, working mainly with Lipocalins and their cellular receptors, identifying structural binding / transport motifs and investigating the physiological link between vitamin A uptake and Type 2 Diabetes.
The bacterial Shiga toxin interacts with its cellular receptor, the glycosphingolipid globotriaosylceramide (Gb3 or CD77), as a first step to entering target cells.
Here, we tested whether human gastric cancers, which are among the most aggressive tumor entities, express the cellular receptor of Shiga toxin, the glycosphingolipid globotriaosylceramide (Gb3 / CD77).
Insulin is a hormone carrier that transports nutrients and glucose in the blood and binds them to cellular receptor sites.
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