Sentences with phrase «cellular receptors for»

Myasthenia gravis is caused by a reduction or deficiency in the number of cellular receptors for a specific neurotransmitter, acetylcholine, at the junctions between nerve endings and skeletal muscle cells.

These proteins were originally discovered as cellular receptors for immunosuppressive drugs, including cyclosporin A and FK506.

Aptamers are also being selected against specific cellular receptors for use in cancer therapy.

While the cellular receptors for other rhinovirus types are known, the rhinovirus C receptor had remained elusive.

Scientists funded by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, have identified a cellular receptor for rhinovirus C, a cold - causing virus that is strongly associated with severe asthma attacks.

Not exact matches

To be viable, a hybrid's cellular machinery, for example, a protein and its receptor, must fit smoothly, as a peg in a hole.

He notes, for example, his lab's surprising finding that the mutations connected to transmission do not simply involve the way influenza's hemagglutinin protein binds to cellular receptors, as many researchers assume.

Researchers pinpoint the cellular receptor MRGRPX2 as the main mechanism for opioid - induced itching.»

Further studies will be necessary to identify the preferred cellular attachment and internalization receptors for TMAdV.

The Cell Surface Signalling Laboratory is interested in identifying new therapeutic targets for both genetic and infectious diseases by using large - scale systematic approaches to discover receptor - ligand interactions that are essential for cellular recognition processes.

The BMP protein acts as an activator for cell — surface receptors, and initiates cellular processes and signaling cascades.

For instance, three scavenger receptor genes were suggested to facilitate the cellular uptake of carotenoids in the adductor muscles of orange - adductor Yesso scallop [13].

They can also spur chronic inflammation and other bad cellular behavior by interacting with the receptor for AGEs, RAGE.

Further, there is evidence to suggest that AGEs produce raised levels of chronic inflammation by altering cellular behavior through the receptor for AGEs, RAGE.

This family of proteins is responsible for a vast array of cellular communication — including the light - sensing molecules in your retinas, the sugar sensors in your gut, and many of the neurotransmitter receptors that underlie the thoughts and emotions that move through your brain — and these proteins are the targets of the vast majority of pharmaceutical drugs.

Huntingtin null neurons exhibit a significant reduction in transcripts encoding proteins destined for the extracellular space, many of which are components of the extracellular matrix or involved in cellular adhesion, receptor binding and hormone activity.

In the worm, we are developing tools to monitor neuromodulation at cellular resolution in an intact brain and using them to directly measure endogenous peptide release and binding to receptors on identified neurons using real - time approaches for imaging neuropeptide signaling, in order to understand the dynamics of this process in a living animal.

Our strong expertise allows us study lipid - protein interaction based phenomena at different scales, from the organ and cellular systems down to minimal synthetic systems in which we can control the proteins as well as the lipid, for instance to monitor the allosteric effects of specific lipids on fundamental receptors such as the EGF receptor (Coskun et al (2011) PNAS) and the insulin receptor.

Insulin binds to many cells in the body having appropriate receptors for the peptide hormone and causes a general uptake in cellular glucose.

Because estrogen and progesterone receptor sites are very similar at the cellular level, estrogen receptor sites can «wake up» when occupied by progesterone molecules, enhancing the action of estrogen for a short period of time.

The IV therapy consists of amino acids (the natural building block of protein) combined with vitamins and nutrients is administered intravenously in order to flood the brain, restoring neurotransmitters, manufacturing new neurotransmitters and receptors which promotes healing of the damaged area of the brain and allows for increased cellular energy production.

Moreover, since hormone receptors reside on the cellular membrane, a reduction in membrane inflammation makes the diet very effective for healing hormone - related conditions, including weight - loss resistance.

Either scenario may occur for genetic reasons due to inherited defects of pancreatic islet cells, cellular insulin receptors, or both.