Sentences with phrase «cellular regulation»

Of particular importance is the BCAA leucine, a potent independent stimulator of muscle protein synthesis in cell culture and animal models through enhanced cellular regulation of mRNA translation (29).
We also have research interests in cellular regulation by ADP - ribosylation, which links epigenetics to metabolism; NUDIX hydrolases, which are involved in regulating intracellular levels of various nucleotides; and sphingolipid biosynthesis, which has strong links to both inflammation and cancer, and where mutations in the various proteins involved are associated with a variety of rare diseases.
We also have research interests in cellular regulation by ADP - ribosylation, which links epigenetics to metabolism; lipid kinases; and sphingolipid biosynthesis, which has strong links to both inflammation and cancer, and where mutations in the various proteins involved are associated with a variety of rare diseases.
His research focuses on molecular mechanisms that orchestrate cellular regulation through protein - RNA interactions.
The research project is part of the Collaborative Research Center 1036 (SFB 1036), which pursues research on basic mechanisms of cellular regulation within the DKFZ - ZMBH alliance.
The use of photo - clickable miRNAs may reveal more miRNA - involved cellular regulation pathways and more possible miRNA targets with pathological importance.
Analysis of endogenous small RNAs indicated that a fraction derive from a biosynthetic mechanism that is similar to that of secondary siRNAs formed during RNAi, suggesting that small antisense transcripts derived from cellular messenger RNAs by RdRP activity may have key roles in cellular regulation.
Dr. Croft's research focus is on the cellular regulation of immunity and tolerance, and how membrane bound and soluble stimulatory molecules control function of T cells and cells such as epithelial cells and fibroblasts that contribute to inflammatory and autoimmune disease.
As we gain a deeper understanding of the cellular regulation mechanisms of Tau function, we will shed more light on the complex role of Tau in the aetiopathogenesis of neurodegeneration.
One such disease that results from a malfunction in cellular regulation is cancer.
The cellular regulation of skeletal muscle protein synthesis has been well described (28, 29).
Although these findings are intriguing, the cellular regulation of skeletal muscle proteolysis in response to negative energy balance and manipulations in dietary protein is not well described.
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