Sentences with phrase «cellular repair machinery»

They protect chromosome ends from being mistaken for broken pieces of DNA that would otherwise be fixed by cellular repair machinery.

They discovered that the DNA repair outcomes, namely the collection of insertions and deletions that are produced by the cellular repair machinery following DNA cutting, generate reproducible patterns at each target site.

Not exact matches

Stalled transcription complexes don't just lend DNA repair processes a helping hand; they can also end up causing double - strand breaks by interfering with the cellular machinery that replicates DNA.

Generation of reactive oxygen species, or free radicals such as superoxide and hydrogen peroxide, is a normal byproduct of metabolism, but can damage cellular machinery when excessive and impair the production of cellular energy, which becomes a vicious cycle as energy - intensive repair processes become untenable (25, 26).