The phrase
"cellular response" refers to how a cell reacts or changes in response to a certain stimulus or external factor. It could include actions such as dividing to make more cells, releasing chemicals or signals, or altering its behavior to adapt to the situation.
Full definition
It is increasingly recognized that spatial and temporal aspects of molecular interactions and activity are key for
correct cellular responses.
Healthy human cells typically turn on nearly half of their 20,000 genes at any given time, and they choose those genes carefully to produce the
desired cellular responses.
It is increasingly recognised that spatial and temporal aspects of molecular interactions and activity are key for
correct cellular responses.
Hydrogen peroxide and other ROS
mediate cellular responses in aging and myriad common chronic diseases, including diabetes, heart disease, stroke, cancer, and neurodegeneration.
They found that both D - GLP1 and D - PTH elicited
cellular responses similar to their natural counterparts but had a longer - lasting effect.
The cell density of cartilage is also very low, therefore, cell cultures offer an easier approach to
study cellular responses of chondrocytic cells, e.g., to mechanical stimuli.
A leukocyte activation test identifies food items which induce release of DNA by innate immune peripheral blood leucocytes Irma Garcia - Martinez, Theresa R. Weiss, Muhammad N. Yousaf, Ather Ali † and Wajahat Z. Mehal † † Contributed equally Published in BioMedCentral, Nutrition and Metabolism View Publication Abstract Background Leukocyte activation (LA) testing identifies food items that induce a patient
specific cellular response in the immune system,...
Reactive oxygen species trigger
cellular responses by activation of stress - responsive mitogen - activated protein kinase (MAPK) signalling pathways.
«Lots of things bind to heparan sulfate to trigger
various cellular responses, but when active heparanase levels are high, the receptors become degraded, so bound molecules are released and can cause damage to the local tissues,» said Agelidis.
Optical imaging provides another poweful approach for detection of pathogen and
host cellular responses in real - time.
Enhanced medial collateral ligament healing using mesenchymal stem cells: dosage effects
on cellular response and cytokine profile.
For instance, LA and the derivative monolaurin were reported to destroy cell membranes of gram - positive bacteria and lipid - coated viruses, to interfere with main
cellular responses as the activation of transduction cascades and gene transcription, to stabilize cell membranes toward the prevention of bacterial resistance.
Being in a ketogenic state has been shown to
promote cellular responses that ultimately lower inflammation and oxidative stress and optimize energy metabolism.
There he worked on anticancer vaccines, identifying drug targets, preparing vaccine formulations, and
testing cellular responses in vaccinated patients.
The next step in this line of investigation, already in development, is to learn
how cellular responses vary, on a molecular level, among roots of flooded plants when the hormone is not present, which would make it possible to create a response model where this signaling path would play a key role.
Merryman's research into CDH - 11 dates back to 2013, when two of his Ph.D. students compared two studies of heart
valve cellular responses that came to completely different conclusions.
Their findings, published online in the New England Journal of Medicine on Feb. 3, suggest that people with this form of vibratory urticaria experience an exaggerated version of a
normal cellular response to vibration.
Researchers at the University of California, San Diego School of Medicine have, for the first time, described the sequence of
early cellular responses to a high - fat diet, one that can result in obesity - induced insulin resistance and diabetes.
Tucked into the internal surface of the cell's outer membrane, these versatile molecules
coordinate cellular responses to a multitude of signals that impinge from without
As a graduate student, Alex developed arrays of nanowires as cellular - scale syringes and electrochemical probes (Shalek et al, PNAS, 2010; Robinson et al, Nature Nanotech, 2012) and used them to study how biochemical perturbations
alter cellular responses en masse (Chevrier et al, Cell, 2011; Shalek et al, Nano Letters, 2012; Yosef et al, Nature, 2013).
Functional plasticity, i.e. the ability to elicit
differential cellular responses through a single receptor by means of different ligands, is a frequently observed feature in cytokine signaling.
Cellular immunity is critical for long - lived antibody responses, but detailed analysis of
cellular responses requires fresh blood samples, thus we are currently planning to enroll new cohorts in east Africa to address this question.
To
investigate cellular response, we have the ability to measure mRNA levels, splice isoforms, protein levels, and post-translation modifications.
G protein - coupled receptors (GPCRs) are actually a huge protein family (i.e., superfamily) of transmembrane receptors that sense molecules outside Eukaryotic Cells in species ranging from yeast to humans, and activate very basic biological pathways and
cellular responses inside the cells.
On the other hand, histidine kinases allow bacteria, plants, and fungi to sense and respond to their environment, regulating a number of
cellular responses such as osmoregulation, chemotaxis, sporulation and microbial pathogenesis (37).
Still, the rewards far outweigh the frustrations, as an understanding of allostery can lead to the physical control of molecular switches and
downstream cellular responses.
Systems biology aims to study complex cellular systems by systematically stimulating them,
monitoring cellular responses, formulating mathematical and computational models to understand the data, and proposing new experiments to refine these models.
Bethesda, Md., Thurs., Sept. 11, 2014 - Building on a successful three - year pilot project, the National Institutes of Health has awarded more than $ 64 million to six research institutions to create a database of
human cellular responses, the Library of Integrated Network - based Cellular Signatures (LINCS).