Sentences with phrase «cellular responses as»

Not exact matches

In addition, Red Star Nutritional Yeast contains other beneficial components, such as beta - 1,3 glucan and mannan, complex carbohydrates known to improve the immune response and help maintain cholesterol levels that are already within a healthy range; trehalose, a disaccharide that helps maintain the health of brain cells; and glutathione, an antioxidant that plays an important role in cellular defense mechanisms.

As a basic researcher, he has been most interested in looking for ideas that point toward new directions in the field: a new role for a protein or a new understanding of how cellular proteins drive the immune response.

They showed that ZIKV infection of cortical progenitors (stem cells for cortical neurons) controlling neurogenesis triggers a stress in the endoplasmic reticulum (where some of the cellular proteins and lipids are synthetized) in the embryonic brain, inducing signals in response to incorrect protein con - formation (referred to as «unfolded protein response»).

For instance, Dawson says, Autism Speaks is funding studies investigating the idea that disorders in the cellular powerhouses, mitochondria, might influence responses to immune challenges such as infection and immunization.

Professor Fallon said: «This identification of an early stage cellular checkpoint that can act as a break on allergic responses has important implications for the development of new therapeutic approaches for asthma and other allergic diseases.»

Interest in studying tRNA fragments has been increasing swiftly as studies have shown that the fragments have regulatory roles and implicated individual fragments in cellular processes such as translation initiation, response to viral infection, response to DNA damage, etc..

Scientists use it as a model organism for studying cellular signals, disease, and the movement of cells in response to a chemical stimulus (chemotaxis).

They may be able to go back further, identifying a persistent inflammatory response deep within the brain or capturing the period when mitochondria, the cellular powerhouses, begin spewing toxins as early as middle age.

AMPK (adenosine monophosphate - activated protein kinase) is an enzyme that acts as a metabolic master switch and is activated in response to low cellular energy levels.

In NHPs specifically also BCG will be evaluated as a gold standard and benchmark vaccine inducing cellular responses for comparison to human data.

In the past 27 years, we have found that this cycling sugar modification of proteins — called O - linked N - acetylglucosamine, or O - GlcNAc — is nearly as common as protein phosphorylation and often competes with it at the same or proximal sites on proteins to regulate nearly every cellular process in response to nutrients and stress.

«In a stressed intestinal environment,» the authors note, «retinoic acid, which was thought to lessen inflammation in the intestine, acted as an adjuvant that promoted rather than prevented inflammatory cellular and humoral responses to fed antigen.»

Previous studies have found proteins and cellular factors involved in rapid - response energy dissipation when light intensity suddenly changes, such as when clouds move past the sun.

Numerous studies have demonstrated activity of these agents against a wide variety of cancers, especially cancer stem cell - like subpopulations, by a host of different mechanisms which comprise inhibition of signaling pathways, of mitochondrial respiration, as well as of cellular stress responses and others.

Further, cellular defense mechanisms, such as the innate immune responses are mainly directed outwards to protect the organism against irritants, pathogens, or injured cells.

On the other hand, histidine kinases allow bacteria, plants, and fungi to sense and respond to their environment, regulating a number of cellular responses such as osmoregulation, chemotaxis, sporulation and microbial pathogenesis (37).

However, it was difficult to test this hypothesis experimentally as the cortex is connected to other cellular structures that generally contribute to the cellular force response in cell - mechanical probing.

In 1963, Hruban and colleagues showed that damaged structures within a cell were sequestered and degraded, and that this was a normal and beneficial response to cellular injuries such as starvation or oxygen deprivation.

Thus, discovery of the immune responses and progression of pathogenesis, as well as eventual countermeasure impact by the delivered drug / vaccine, can be greatly aided by live cellular and animal imaging.

Still, the rewards far outweigh the frustrations, as an understanding of allostery can lead to the physical control of molecular switches and downstream cellular responses.

In response to cellular stress such as DNA damage, oncogene activation, transcriptional inhibition, and hypoxia, tumor suppressor p53 is activated and expressed, and acts as a transcription factor to induce its target genes [1], thereby playing a central role in the regulation of DNA repair, cell cycle, apoptosis, senescence, and angiogenesis [2 - 4].

Stimulation of gamma waves reduced levels of amyloid - β, decreased phosphorylation of tau, and led the brain's immune cells — microglia — to perform their usual housekeeping role, clearing away cellular debris, including amyloid - β (as opposed mounting an inflammatory response as microglia do in Alzheimer's disease, Tanzi explained).

In 2010, we formally demonstrated ADE by developing a mouse mode of ADE - mediated disease, and we began to dissect the contribution of humoral vs. cellular immune components in dengue vaccine - mediated protection using model vaccine candidates as tools to probe the mechanisms by which the vaccine - induced immune responses in mice contribute to protection vs. ADE.

We examine the molecular and cellular mechanisms through which androgens and estrogens, as well as the neuropeptide vasotocin, affect behavioral and brain responses to sensory cues that elicit different types of social output, from courtship to aggression to withdrawal.

The translation of extracellular, chemical information into the correct cellular response is a process known as signal transduction.

Genotype correlations with the immune system as a whole, as well as with cellular responses to different stimuli, provides a valuable platform for the understanding of functional impact of disease associated variants.

(ii) the carbohydrates on the surface can serve as targeting molecules and trigger cellular uptake via specific receptors or mediate specific cellular responses [10].

I'm also interested in better understanding individual differences in responses to damages as well as differences in cellular responses, particularly stem cells.

Moreover, the data can serve as a basis for studies concerning the evolution of signaling mechanisms, as well as can give specific insights into the regulation of basic cellular processes such as polar cell growth, cell expansion, plant morphogenesis and the plants responses to fungal pathogens.

BETHESDA, MD, — The Foundation for the National Institutes of Health (FNIH) has selected Whitehead Institute Member David Sabatini to receive its fifth annual Lurie Prize in Biomedical Sciences for discovery of the mTOR (mechanistic target of rapamycin) cellular pathway as a key regulator of growth and metabolism in response to nutrients.

Increasing attention is being paid to mitochondrial dysfunction as a contributor to many diseases because these organelles lie at the cross roads of sensing and integrating cues from the environment to trigger adaptive and compensatory cellular responses.

When incorporated into the cell membranes of the body, these omega - 3 and omega - 6 fatty acids function as precursors for eicosanoids that control a host of cellular functions and responses.

Bananas also contain small amounts of beta - carotene, which gives bananas with their yellow color and provides an additional source of vitamin A. Collectively, these vitamins support a number of physiological processes; vitamin A promotes healthy cellular growth; vitamins C and E serve as antioxidants that help prevent disease; vitamin K helps your body form blood clots in response to injury; and the B - vitamins support your metabolism.

Inflammation is part of the complex biological response of vascular tissues to a harmful stimuli, such as bacteria, viruses, parasites, damaged cells, or different cellular irritants.

A multitude of plant hormetic compunds such as polyphenols, flavanols, luteolin, apigenin, anthocyanins, and pterostilbene — these compounds actually induce a small stress response in our cells which build cellular resilience and health

The chart below summarizes a study that found there may not be as much to it as we think, other than simply chasing the muscle pump to elicit blood flow response and anabolic triggering, cellular swelling, hypertrophy, etc..

PEITC shares the same - N = C = S reactive bit as sulforaphane from broccoli, and the much the same cellular mechanism (induction 100s of genes with the Antioxidant Response Element promoter, mediated by Keap1 - Nrf2).

«Hormesis in aging is defined as «life - supporting beneficial effects resulting from the cellular responses to single or multiple rounds of mild stress.»

Among berries, I mostly consume strawberries (daily morning smoothie with a cup of frozen strawberries, half banana, cup water, 3 tbsp flax seed, 2 tbsp wheat germ), as their flavonoid, fisetin, appears particularly potent in inducing cellular stress responses and crossing the blood brain barrier.

These services operate by using the vehicle's built in cellular technology, as well as its GPS system, to connect Toyota drivers to 24 - hour Toyota response center.

Bee (Hymenoptera) envenomation may include stings from honeybees, bumblebees, yellow jackets, hornets and wasps — and the ASPCA Animal Poison Control Center warns that components of venom can create cellular injury, elicit an inflammatory response, trigger histamine release and act as a possible allergen.

Vitamin A and E have been shown to enhance immune function in small animals, as the former can beneficially influence T - helper responses, and the latter is known to improve both cellular and humoral immunity.

Her research was focused on the genetic and cellular response to cardiac injury such as heart attack.

Our study also suggests that cellular responses to future ocean conditions are not likely to be straightforward, as shifts in calcification may have less to do with calcification - related genes and more to do with intracellular regulatory processes in cells grown under continuous culture for many hundreds of generations.