Sentences with phrase «cellular roles»

A total of 1738 predicted protein - coding genes were identified; however, only a minority of these (38 percent) could be assigned a putative cellular role with high confidence.

Each form of the enzyme appears to have different cellular roles — i.e., allows the organism to use carbon monoxide in a different way.

These models can be used to explore the cellular role of PCSK9 in vitro and to test the efficacy of cholesterol - lowering agents.

Whether a protein is found in the nucleus, cell membrane, or mitochondria can provide clues to the protein's cellular role.

Overexpression of fluorescently tagged proteins can lead to improper protein localization, protein aggregation, or disruption of normal protein function, and ultimately misinterpretation of the protein's cellular role.

Now a research team led by Broad Institute Imaging Platform director Anne Carpenter and postdoctoral fellow Mohammad Rohban has shown that a high - throughput, computerized imaging technique for studying morphology, called Cell Painting, can provide insight into the cellular roles of genes or disease - linked gene alleles whose function or impact is unknown.

These channels are excellent molecular candidates to fulfil a range of sensory and / or cellular roles that are well characterised physiologically.