Sentences with phrase «cellular signaling mechanism»

Writing in the June 9 online edition of Nature Genetics, the scientists reveal a cellular signaling mechanism in place at the earliest developmental stage.

He worked in various disciplines including vaccinology, immunology, stem cell biology, cellular signaling mechanisms, and monoclonal antibody therapy of tumors.

Not exact matches

Information theory analysis of cell signaling reveals mechanisms for reliable cellular responses despite signal variability.

«The mechanism we demonstrated is the most sensitive cellular thermometer known to date, since the signaling pathways that trigger a heat shock or cold shock hardly react in this physiologically relevant temperature range,» explained Prof. Dr. Florian Heyd.

It thus seems quite likely that this new signaling path also links the performance of the cellular power plants and cell division in human cells,» says Meisinger, who now plans to analyze these mechanisms in tumor tissues.

«Almost nothing is known» about the molecular and cellular mechanism by which water is detected in the mouth and throat, and the neural pathway by which that signal is transmitted to the brain, says Zachary Knight, a neuroscientist at the University of California, San Francisco.

Busulfan selectively induces cellular senescence but not apoptosis in WI38 fibroblasts via a p53 - independent but extracellular signal - regulated kinase - p38 mitogen - activated protein kinase - dependent mechanism.

We are interested in understanding the molecular mechanisms of proteins involved in cellular signalling, especially protein kinases.

Numerous studies have demonstrated activity of these agents against a wide variety of cancers, especially cancer stem cell - like subpopulations, by a host of different mechanisms which comprise inhibition of signaling pathways, of mitochondrial respiration, as well as of cellular stress responses and others.

Understanding the underlying mechanisms allows identifying putative sites for pharmacological intervention and opens the prospect of engineering artificial molecular switches derived from the highly efficient systems that have evolved for cellular signal transduction.

Kontoyiannis D., Boulougouris G., Manoloukos M., Armaka M., Apostolaki M., Pizarro T., Kotlyarov A., Forster I., Flavell R., Gaestel M., Tsichlis P., Cominelli F., Kollias G., 2002, «Genetic dissection of the cellular pathways and signaling mechanisms in modeled tumor necrosis factor - induced Crohn's - like inflammatory bowel disease», JEM, 196, 1563 - 74.

There is also another mechanism by which cellular amino acid nutrition impacts on mTOR signalling; this involves the amino acids generated within the lysosomes by intracellular protein degradation and autophagosomal digestion [23,24].

Our goal is to identify conserved signaling mechanisms through which the nervous system may exert its control over the cellular protective machinery.

Moreover, the data can serve as a basis for studies concerning the evolution of signaling mechanisms, as well as can give specific insights into the regulation of basic cellular processes such as polar cell growth, cell expansion, plant morphogenesis and the plants responses to fungal pathogens.

Autophagy, the body's mechanism for the removal and recycling of cellular waste, is key to rejuvenation, especially in the mitochondria, and is allowed to proceed only in the postabsorptive state, in which insulin signaling ebbs to its lowest (basal) level.

However, the finite mechanisms by which cellular signaling molecules function in concert to regulate skeletal muscle mass in response to nutritional manipulation remain to be elucidated.

Google will allow wireless carriers to define signal bars in Android P, providing them with the ability to change the operating system's mechanism for representing mobile signal strength on devices with cellular connectivity, XDA Developers reports, citing a number of commits recently discovered in the main repository of the Android Open Source Project.