Sentences with phrase «cellular signaling pathways»

«This occurs when CSN6 is deregulated through a series of cellular signaling pathways.»

The transcription of non-coding regions in the genome is precisely regulated by cellular signaling pathways — and on a grand scale: up to 80 per cent of the RNA copies were non-coding.

«We now know which cellular signalling pathways are involved in liver tumour development,» explains Heikenwälder.

«We discovered that CSL produces a protein similar to one involved in a major cellular signaling pathway in other organisms, including plants and animals» corresponding author Takuya Matsuo says.

This landmark revelation was the first definition of an entire cellular signaling pathway from the cell surface to the nucleus, providing an important paradigm for understanding intracellular signaling.

Sirtuins are enzymes regulating the expression of genes that control the function of cells through key cellular signalling pathways.

Study identifies cellular signaling pathway that enables breast cells to resist tissue changes during tumor development and is associated with better prognosis

In addition to their antioxidant properties, these polyphenolic compounds exhibit neuroprotective properties by their interaction with cellular signaling pathways followed by transcription and translation that mediate cell function under both normal and pathologic conditions.

Researchers uncovered evidence that a common cellular signaling pathway is associated with aggressive hemangiosarcoma tumor growth and chemotherapy resistance.

Once there, the protein acts on the osteoblasts and inhibits Wnt activity, which is a cellular signalling pathway that is involved in the formation of the skeleton and in certain disorders, such as osteoporosis, arthritis and myeloma.

Meanwhile, cancer genome projects have yielded unprecedented insights into the cellular signaling pathways that drive the development and progression of cancer — information that has led to effective therapies tailored for individual patients.

Surprisingly, we found that high levels of potassium, which was released by dying cells in tumours, had very little effect on calcium but blocked activation of a cellular signalling pathway called the PI3K pathway when T cells encountered tumour antigens».

ln hOSA, the Hedgehog (HH) developmental and cellular signaling pathway has been documented to contribute to the pathogenesis of the disease, impacting genes responsible for tumor formation and metastasis.