It is caused by a mutation in the ACVR1 gene, which over-activates
a cellular signaling process that is important for embryo development and involves a protein called BMP.
Luo and Qiu lead a research team that identified an enzyme that could independently accomplish ubiquitination, an important
cellular signaling process being pursued as a therapeutic target.
Researchers identified a single enzyme doing the work of a trio thought necessary to control a common
cellular signaling process being pursued as a therapeutic target.
They not only custom - coded the smartphone control algorithms, but designed the engineered cells to produce insulin without any «cross-talk» between normal
cellular signaling processes.
His research group focuses on big data network biology, exploring biological systems by developing and deploying algorithms aimed to predict cell behavior, in particular looking at
cellular signal processing and decision making.
Not exact matches
Calcium - based
signaling is used in many
cellular and neuronal
processes to initiate rapid responses to extracellular
signals.
The AXIN2 protein interacts with proteins in the Wnt
signalling pathway, which is involved in controlling many
cellular processes, including development.
The authors hypothesize that these activities are components of
cellular reconfigurations that are involved in
processing communication
signals essential for social organization.
Through the mTOR
signalling pathway, it is involved in the regulation of many
cellular processes, including cell survival, metabolism, proliferation, differentiation, and senescence.
Cell
signaling is a complex
process where interactions between cells and their environment govern basic
cellular functions and activities.
Among their many functions,
signaling pathways regulate biological
processes required for
cellular survival.
In prior, unrelated experiments, the same species of worm had become hypersensitive to smell when its nerve cells experienced problems with dopamine
signaling, a
cellular process that helps control how readily cells can communicate with one another.
The budding yeast, Saccharomyces cerevisiae, is a prime organism for studying fundamental
cellular processes, with the functions of many proteins important in the cell cycle and
signaling networks found in human biology having first been discovered in yeast.
Traditional hydrogels made up of either synthetic polymers or natural biomolecules often serve as passive scaffolds for molecular or
cellular species, which render these materials unable to fully recapitulate the dynamic
signaling involved in biological
processes, such as cell / tissue development.
Once receptors sense the presence of these binding partners, they send out new
signals that initiate other
cellular processes.
I studied the
process called
signal transduction - transmission of the activating mechanical
signal from outside the cell, across the
cellular membrane, to FAK inside the cell, leading to the activation of the kinase.
The Cell Surface
Signalling Laboratory is interested in identifying new therapeutic targets for both genetic and infectious diseases by using large - scale systematic approaches to discover receptor - ligand interactions that are essential for
cellular recognition
processes.
The BMP protein acts as an activator for cell — surface receptors, and initiates
cellular processes and
signaling cascades.
Multiple effects of a novel epothilone analog on
cellular processes and
signaling pathways regulated by Rac1 GTPase in the human breast cancer cells.
The Cell Surface
Signalling Laboratory investigates the molecular basis of
cellular recognition
processes to identify new therapeutic targets for both genetic and infectious diseases.
Wnt / beta - catenin
signaling is a tightly regulated, multi-functional pathway involved in in many
cellular processes, including
cellular decisions about proliferation versus differentiation.
Others were unanticipated, including significant differences in expression levels among genes involved in fundamental
cellular processes such as ribosomal biogenesis, transfer RNA
processing, and Notch -
signaling — part of a complex system of communication that governs basic
cellular activities and coordinates cell actions.
In the worm, we are developing tools to monitor neuromodulation at
cellular resolution in an intact brain and using them to directly measure endogenous peptide release and binding to receptors on identified neurons using real - time approaches for imaging neuropeptide
signaling, in order to understand the dynamics of this
process in a living animal.
By defining the
processes behind these
cellular signals, the blueprint for the heart, we hope to one day recreate them through chemical methods — using drug cocktails to coax stem cells into becoming heart cells at just the right time and place.
Sphingolipid metabolites, such as ceramide, sphingosine, and sphingosine -1-phospate are lipid
signaling molecules which are involved in diverse
cellular processes.
The Center for Cell Circuitry addresses the enormous therapeutic potential of
cellular circuits, which connect individual molecular components and allow cells to
process signals and control decision - making.
The translation of extracellular, chemical information into the correct
cellular response is a
process known as
signal transduction.
The Reactome Knowledgebase (https://reactome.org) provides molecular details of
signal transduction, transport, DNA replication, metabolism, and other
cellular processes as an ordered network of molecular transformations - an extended version of a classic metabolic map, in a single consistent data model.
Our research aims at understanding the spatial and temporal regulation of
signaling molecules that underly
cellular processes.
The translation of extracellular, chemical information into a
cellular state change is a
process known as
signal transduction.
Moreover, the data can serve as a basis for studies concerning the evolution of
signaling mechanisms, as well as can give specific insights into the regulation of basic
cellular processes such as polar cell growth, cell expansion, plant morphogenesis and the plants responses to fungal pathogens.
HGH, along with insulin growth factor 1 (a hormone secreted by the liver after it receives
signals from HGH) stimulate the
process of
cellular regeneration in the body.
This is a way of slowing down the aging - related
processes, improves brain functioning and memory capacity, strengthens and stabilizes
cellular membranes which is crucial for cell
signaling and energy transfer.
NO is critical
signalling molecule involved in many
cellular and physiological
processes, including, but not limited to: blood circulation, immune defence and neurotransmission.
For example, when biting into an apple, the body will immediately
signal a complex sequence of messages and
processes to break down the apple into energy and essential structural nutrients for
cellular repair and replacement.
Not only that, saturated fatty acids are important for
cellular membranes, normal hormone production, organ padding, calcium absorption and immune function, as well as
signaling and stabilization
processes in our bodies.