Sentences with phrase «cellular source of»

PEMF therapy treats the cellular source of swelling by recharging the cells with a mild electromagnetic current.

This discovery leads to a major revision of previous paradigm by broadening focus of anti-aging drug discovery and development to include a new likely cellular source of age - associated chronic systemic sterile inflammation.

The second experiment is to isolate various cell types from lungs harboring metastasis to confirm the cellular source of periostin in response to metastatic growth.

CML stem cells, the cellular source of a vast majority of differentiated CML cells, are reportedly responsible for the recurrence of CML, following TKI therapy.

We use the Cre - loxP recombination system to generate mice with cell type - specific inactivation of the IL - 10 gene in order to identify cellular sources of the cytokine that are relevant in various situations of immune challenge.

Not exact matches

The heart is a great source of CoQ10, which is essential for normal cellular function and heart health.

This lectin binds to the membranes of T - cells in the body and interferes with cellular metabolism when consumed in sufficiently large quantities (SOURCE).

Non-denatured whey protein is one of the best food sources for boosting cellular anti-oxidants such as glutathione which is your body's master antioxidant.

Hemp is a great source of sulfur containing amino acids methionine and cysteine which are necessary for cellular detoxification and the production of vital enzymes.

Mitochondria, specialized organelles found in nearly every cell of the body, use cellular respiration to generate one of the most important sources of chemical energy — adenosine triphosphate (ATP), a versatile nucleotide that powers everything from cell division to cell signaling to transportation of large molecules across the cell membrane.

Researchers have used new techniques and one of the brightest X-ray sources on the planet to map the 3 - D structure of an important cellular gatekeeper in a more natural state than possible before.

Tapping into an ancient cellular energy source may help stave off the rigors of surgery and the ravages of age.

«Induced pluripotent stem cells have tremendous potential as a source for personalized cellular therapeutics for organ repair,» said Joseph Wu, MD, PhD, director of the Stanford Cardiovascular Institute.

The technique, which is described in the study «Detection of interferon - protein reveals differential levels and cellular sources in disease» published April 18 in The Journal of Experimental Medicine, will aid the diagnosis and treatment of numerous autoimmune diseases, including systemic lupus erythematosus (SLE) and dermatomyositis.

To accomplish this deception biologically, Bartfai and Conti genetically engineered mice to overexpress uncoupling protein 2, which causes the mitochondria in cells to produce heat instead of ATP, the fuel source of cellular activity.

Human Embryonic Stem (hES) cells derived from Preimplantation Genetic Diagnosed (PGD)- embryos offer a new alternative source of cellular model as they can be largely expanded, differentiated in several cell types and harbors «naturally» the causative mutation of the pathology.

The influence of cellular source on periodontal regeneration using calcium phosphate coated polycaprolactone scaffold supported cell sheets.

Basically what was happening when you use a hematopoietic stem cell to correct an inherited metabolic disease is that through engraftment of that cell you are allowing that cell to become the replacement source for the missing enzyme or other factor - almost like a cellular form of gene therapy or, as I call it, «poor man's gene therapy».

LifeMap Discovery ® is a compendium of embryonic development for stem cell research and regenerative medicine, constructed by integrating extensive molecular, cellular, anatomical and medical data curated from scientific literature and high - throughput data sources.

Scientists create organoids from a variety of cellular sources, including induced pluripotent stem cells.

«I highly respect Novocell technologies and am pleased to collaborate with Novocell and explore the potential of their hES cell to islet cell advances in combination with our iPS cells as a potential new sources for the generation of cellular models and therapies for diabetes,» said Dr. Yamanaka, Director of Center for iPS Research and Application at Kyoto University.

The excitement surrounding cellular reprogramming and the possibility of federal funding for human embryonic stem cell (ESC) research in the US could be overshadowing another promising therapeutic source of stem cells: those derived via parthenogenesis, some researchers say.

The routine use of MSC cellular therapy with would benefit from a uniform cell source, with stable phenotype and function as well as providing a solution to potential safety issues.

Therefore, this work provides strong support for the use of iPSC ‐ derived MSC as a more uniform with well ‐ defined phenotype and function as a sustainable source of cells which paves the way for a clinical application for IBD cellular therapy.

Novocell has developed and proven methods to efficiently generate pancreatic, insulin - producing cells from hESCs, demonstrating for the first time that hESCs could serve as a source of cellular therapy for diabetes.

The cells had defective mitochondria — cellular power stations — and depleted levels of ATP, which is their most important fuel source.

These findings have identified an alternative source of replacement tissue for use in human retinal cellular therapies, and provide a new in vitro cellular model system in which to study RPE diseases affecting human patients.

Alternative splicing is commonly believed to be a major source of cellular protein diversity.

Certain particle compounds may directly generate ROS in vivo because of their surface chemistry (eg, metals, organic compounds, and semiquinones) or after bioactivation by cytochrome P450 systems (eg, polycyclic aromatic hydrocarbon conversion to quinones).6, 290 a, 290 b A particle surface or anions present on otherwise more inert particles may disrupt iron homeostasis in the lung and thereby also generate ROS via Fenton reactions.291 Other PM constituents may do so indirectly by the upregulation of endogenous cellular sources (eg, nicotinamide adenine dinucleotide phosphate [NADPH]-RRB- oxidase) 292,293 or by perturbing organelle function (eg, mitochondria) by taken - up PM components.261 Particle stimulation of irritant and afferent ANS fibers may also play a role in local and systemic oxidative stress formation.294 Given the rich antioxidant defenses in the lung fluid, secondarily generated oxidization products of endogenous molecules (eg, oxidized phospholipids, proteins) or a reduction in endogenous antioxidants per se may be responsible at least in part for the state of oxidative stress in the lungs (along with instigating the subsequent cellular responses) rather than ROS derived directly from PM and its constituents.

When endurance athletes train, they use up the glycogen in their muscles, but when bodybuilders train they use adenosine triphosphate (ATP) which is a whole other fuel source and also a major source of energy for most cellular functions in a human body.

The authors of the study explain that their findings suggest that ketogenic diets could also potentially help normalize pathological behaviors in the human model of schizophrenia by providing alternative energy sources via ketones, the products of fat breakdown, which would substitute the abnormally functioning cellular energy pathways in the brains of people suffering from this disease.

I also make sure to get enough food and supplemental sources of glutathione and its precursors when pregnant to avoid inflammation and cellular stress as much as possible.

Dr. Wahls explains why some fats are actually essential to good cellular and brain health, and which sources of fat should be avoided.

These foods, along with her other suggested food of brightly colored vegetables are an excellent source of antioxidants and know to support cellular health.

Neutrophils, eosinophils, and macrophages are also sources of cellular ROS.32

These single - celled phytoplankton don't depend on the digestive system or liver for processing, making them an extremely bioavailable source of nutrients on a cellular level.

In that context, our carbohydrate intake should be low to moderate (only from cellular sources, not as flour), rich in leafy, sulphur - rich and colourful vegetables, moderate in fruit and with a high content of natural fats such as butter, extra virgin olive oil, coconut oil and animal fats.

Definition of toxin: any substance that creates irritating and / or harmful effects in the body A. External sources: pollution B. Internal sources: cellular wastes C. Any substance if too much, like water, sodium and almost all nutrients (in certain situations can cause a toxic environment 2.

Free radical damage caused by electron - seeking, highly reactive, oxidative molecules has been identified as the source of many maladies through mechanisms such as inhibition of telomerase, changes to cellular permeability and DNA damage.

It is used for cellular support, a source of strong antioxidant activity, and for mood support.

First proposed in 1972, the mitochondrial theory of aging suggests that it's free radical damage to our cells» power source, known as mitochondria, that leads to a loss of cellular activity and function over time.

The fuel sources for aerobic cellular metabolism are fats and carbohydrates, with a greater percentage of calories coming from fats at lower intensities.

Use Vegan Single Source SBT both internally and externally for its many healing properties; SBT Vegan Single Source supports cellular regeneration as a component of the skin fat and creates a silky soft and smooth feeling.

The mitochondrial theory of aging suggests that free radical damage to our cells» power source (mitochondria) leads to a loss of cellular energy and function over time.

Together, these natural sources of antioxidants help protect cellular health and DNA integrity, while supporting immunity and overall vitality.

In the mitochondria, which are easily damaged due to their role as the energy production factories in cells and can themselves become a key source of cellular damage, adequate autophagic waste recycling is critical for rejuvenation but diminishes in aging cells.

Spinach is also a great source of beta - carotene, a precursor of vitamin A, necessary for cellular regeneration and good eye health.

These trace minerals are essential to many cellular and organ functions and due to soil depletion, we are likely not getting enough of them through our food sources.

«Cells depend on cellular respiration as an energy source and during periods of food deprivation or in the absence of glucose, these cells can also resort to ketosis as an additional source of energy.»

They are also a good source of copper that helps in the production of energy at the cellular level.