Sentences with phrase «cellular stress response»

of aberrant amyloid and tau in the retina, quantification of any neuronal degeneration, delineation of cellular stress responses of neurons and particularly glial cells, and investigation of oxidative stress.

Intermittent fasting, regular exercise and consumption of dietary phytochemicals can have a major positive impact on health by bolster - ing adaptive cellular stress response pathways that protect against and counteract a range of major diseases.

Some, like glucoraphanin (precursor to sulforaphane), mostly in broccoli sprouts and broccoli, are likely considerably more potent in inducing cellular stress responses (yes, that's a good thing).

Consistent with a lower thermal tolerance, longfin smelt exhibited a pronounced cellular stress response after exposure to 20 °C that was not observed in delta smelt.

It's a first step in mechanistically understanding how cellular stress responses are wired in specific contexts.»

Analytical endpoints included examination... of aberrant amyloid and tau in the retina, quantification of any neuronal degeneration, delineation of cellular stress responses of neurons and particularly glial cells, and investigation of oxidative stress.

Among berries, I mostly consume strawberries (daily morning smoothie with a cup of frozen strawberries, half banana, cup water, 3 tbsp flax seed, 2 tbsp wheat germ), as their flavonoid, fisetin, appears particularly potent in inducing cellular stress responses and crossing the blood brain barrier.

Consistent with having a lower temperature tolerance, longfin smelt exhibited a pronounced cellular stress response, with an upregulation of heat shock proteins, after exposure to 20 °C that was not observed in delta smelt.

This, in turn, activated a cellular stress response pathway that culminated in the degradation of a protein called CtIP that is required for homologous recombination repair.

This «cellular stress response» helps keep cells alive by buying them time to recover.

The team knew from previous experiments that ISRIB prevents the cellular stress response by stabilizing a protein called eIF2B, which typically helps turn on protein production.

Traumatic brain injury persistently turns on the cellular stress response — and the resulting drop in protein production may slow critical cognitive processes.

Although other tRNA halves have been described before — specifically those that are produced during a cellular stress response — this discovery represents a new and distinct species of tRNA halves that the authors coined SHOT - RNAs, for sex hormone dependent tRNA - derived RNAs.

Besides intracellular signal transduction, a host of other therapeutic targets were discussed for the mediation of the anticancer activity of anthelminthics, ranging from inhibition of mitochondrial respiration, glucose utilization, cellular stress response and others.

Current scientific efforts aim at elucidating the function of mitochondrial Hsp90s in tumor bioenergetics, the regulation of the cellular stress response and the resistance to conventional and targeted anticancer regimens.

Numerous studies have demonstrated activity of these agents against a wide variety of cancers, especially cancer stem cell - like subpopulations, by a host of different mechanisms which comprise inhibition of signaling pathways, of mitochondrial respiration, as well as of cellular stress responses and others.

Mechanistically, survivin is a multifunctional protein, controlling cell proliferation, cell death, the cellular stress response and developmental pathways of tumor maintenance.

Altieri and his team are currently focused on three programs to understand the biology of survivin with respect to cell cycle progression, in particular, mitosis, cell survival and the cellular stress response and how exploiting these pathways may provide new cancer therapeutics.

The identified compounds are not electrophiles, do not deplete cellular glutathione or otherwise incite a cellular stress response.

Previously, Walter's team discovered that ISRIB (short for «integrated stress response inhibitor») blocks this aspect of the cellular stress response by enhancing the activity of a protein called eIF2B, which helps keep a key protein production line operating in stressed cells.

Traumatic brain injury, for example, persistently turns on the cellular stress response, and the resulting drop in protein production may slow critical cognitive processes such as learning and memory, which require brain cells to produce proteins that help create long - lasting connections in the brain.

Longfin smelt exhibited a cellular stress response at a temperature below those at which they can be periodically found in the wild, suggesting that these fish may routinely experience sublethal temperature stress in the Delta.