Daily medium exchanges help alleviate
cellular stresses associated with pH changes and resource consumption due to the high cell density of the culture.
Not exact matches
Pancreas tissue from acutely sleep - deprived aged animals exhibited a marked increase in CHOP, a protein
associated with cell death, suggesting a maladaptive response to
cellular stress with age that was amplified by sleep deprivation.
Telomere length predicts both
cellular health and disease in rodent models and humans.8 Shorter telomeres predict onset of cardiometabolic diseases of aging.9 Chronic
stress is
associated with higher inflammation, shorter telomeres, and lower activity levels of telomerase, the
cellular enzyme that elongates telomeric DNA.10, 11 Levels of amyloid beta (Aβ) proteins circulating in the blood appear to be
stress - related in rodent models12 and may be affected by
stress reduction, and greater Aβ42 / Aβ40 ratios are
associated with lower risk of dementia.13
We have also identified a transcriptional signature of aneuploidy that is
associated with
cellular stress and slow proliferation, and is found in aneuploid primary and cancer cells across a host of organisms.
Taurine is highly effective in eliminating free radicals and keeping the cells healthy and proper taurine supplementation will significantly decrease oxidative
stress and fatigue in muscle tissue, reducing the inflammation
associated with
cellular damage.
Calorie restriction has also been
associated with a reduction in oxidative
stress, perhaps due to a change in the amount of reactive oxygen species produced in the mitochondria during normal
cellular respiration [4] under calorie restricted conditions.
Depression,
associated with compromised integrity of this intestinal barrier, becomes the swirling storm of inflammation, impairment of
cellular machinery (i.e. mitochondria), oxidative
stress, and inflammation in a carousel - like forward rotation.