Sentences with phrase «cellular studies on»
The NRC panel, chaired by neurobiologist Charles Stevens of the Salk Institute in La Jolla, California, looked at more than 500 human, animal, and cellular studies on EMFs and found «no conclusive and consistent evidence... that exposures to residential electric and magnetic fields produce cancer, adverse neurobehavioral effects, or reproductive and developmental effects.
http://www.sciencemag.org/ Not exact matches
During this clinically silent period, however, there may be indicators of dysfunction on a cellular level, such as the elevated levels of S100B antibody found in the cerebral spinal fluid in the football players in the study, even six months after the end of the season, which he said, could «potentially herald -LSB--RSB- the early stages of [chronic traumatic encephalopathy] or CTE.»
The fields within biology are further divided based on the scale at which organisms are studied and the methods used to study them: biochemistry examines the fundamental chemistry of life; molecular biology studies the complex interactions of systems of biological molecules; cellular biology examines the basic building block of all life, the cell; physiology examines the physical and chemical functions of the tissues and organ systems of an organism; and ecology examines how various organisms interrelate.
«While previous studies at McLean and elsewhere have focused on the behavioral symptoms produced by such immune activation, this study goes deeper, going to the cellular level to show how the brain's neural circuits are affected.»
Many studies have shown that stiffness of the extracellular matrix, the fibrous network of collagen that surrounds cells, promotes cellular mobility; cells can get a better grip on stiffer surfaces and thus invade neighboring tissue.
And once I got into brain biology, it became clear you needed to study the brain on the cellular level, and once you began to understand aspects of behavior in the cellular level, you wanted to understand the molecular level.
Today is the 70th birthday of Elizabeth Hay, an embryologist at Harvard Medical School who, through pioneering studies on regeneration of amphibian limbs, has shed light on the cellular mechanisms that transform normal cells into tumors.
Sheng Ding, PhD, a senior investigator in the Roddenberry Stem Cell Center at Gladstone and co-senior author on the study, adds, «This new cellular reprogramming and expansion paradigm is more sustainable and scalable than previous methods.
«Our study is a nice example of how the understanding of a disease on the molecular and cellular level results in new therapeutic options.
«Proper blood cell production is dependent on functioning hematopoietic stem and progenitor cells that are destroyed during conditioning procedures for transplantation or following bone marrow injury,» said the study's first author Kevin A. Goncalves, who performed this research as part of his PhD studies in cellular and molecular physiology at the Sackler School.
Many who study radiation's effects on the cellular level prefer to err on the side of caution.
«To date, there has been no systematic means of assessing the fidelity of cellular engineering — to determine how closely cells made in a petri dish approximate natural tissues in the body,» says George Q. Daley, MD, PhD, Director of the Stem Cell Transplantation Program at Boston Children's and senior investigator on both studies.
Ana Soto, professor of cellular biology at Tufts University School of Medicine, and her colleagues were studying the effects of estrogen on a breast cancer cell line.
David Prangishvili, a virologist at the Pasteur Institute in Paris and a colleague with Forterre in studying viruses that infect archaea, now thinks that viruses swam in the primordial soup prior to the emergence of cellular life of any kind and only later became dependent on cells.
Jacqueline Crisman was on her way to research superstardom studying proteases, chemokines, and the cellular hallmarks of inflammatory bowel disease at Pennsylvania State University when in 2004, motivated by her parents» unstable health, she relocated to be closer to them.
«Ours is the first study to define the dormant niche on a cellular and molecular basis, and it is interesting that the culprit is the tissue we so often assume is a passive bystander, the microvascular endothelium,» Ghajar says.
A new study, however, provides insights on the cellular mechanisms that might be targeted to help certain stem cells - called human mesenchymal stem cells (hMSCs)- maintain properties needed to make them clinically useful.
However, due to technological limitations, previous genetic studies largely focused on mixed populations of cells, obscuring critical nuances in cellular behavior.
While these studies were performed using a cellular model of hypertension, the implication of vitamin D3 on dysfunctional endothelium is much broader.
Now, researchers at the University of Missouri have developed a three - dimensional microscope that will yield unparalleled study of membrane proteins and how they interact on the cellular level.
«This is the first systematic comparison of the mouse and human at the genomic level,» said Bing Ren, Ph.D., co-senior author on the Consortium's main Nature study and professor of cellular and molecular medicine at the University of California, San Diego.
A new study by researchers from the UCSF Benioff Children's Hospital Research Institute (CHORI) shows that a modest 4 milligrams of extra zinc a day in the diet can have a profound, positive impact on cellular health that helps fight infections and diseases.
«Our study on the TACC3 - chTOG interaction will allow cellular biologists and researchers on microtubule dynamics to better understand how microtubule assembly is regulated during cellular division,» says Montoya, and he anticipates that «it could also help in developing new anti-microtubule drugs, providing more effective therapeutic options in cancer treatment.»
Analyses were performed on the frog Xenopus laevis, an animal model widely used by researchers from around the world to study laws governing cellular division in depth.
Future work will focus on identifying cellular targets of ampulexins, and potentially generating a useful animal model for the study of Parkinson's disease treatments.
«When we study the interactions between the host cell and the virus, we get information about both of them and about how cellular machinery is working under viral infection,» says Alessia Ruggieri, a group leader and virologist at University of Heidelberg in Germany and senior researcher on the study.
Animal and cellular studies have found that some phthalates block the effects of testosterone on the body's organs and tissues.
The study is the first, say its authors, to provide evidence that adenosine, a biochemical at the heart of human cellular function, plays another crucial role — keeping on hand a steady number of healthy chondrocytes, the cells that make and sustain cartilage.
«Liver cancer is on the rise worldwide, and in human studies we've now seen that patients can progress from fatty liver disease to liver cancer without any middle steps such as cirrhosis,» says David Moore, a professor of molecular and cellular biology, who led the study with Associate Professor Loning Fu, both at Baylor.
The senior researchers of the study, Martin Eilers and Juha Klefström are excited about the concept that Myc's ability to turn off rather than turn on genes is a key to cell death: «It is much easier to bring cellular activities down than up with the existing drugs.
Pregnant women who had low socioeconomic status during childhood and who have poor family social support appear to prematurely age on a cellular level, potentially raising the risk for complications, a new study has found.
«We now have a tool to control temperature on a cellular level, and we can study how biological systems react to temperature change,» says Peter Maurer, a physicist at Harvard University in Cambridge, Massachusetts, and a member of the team publishing the result today in Nature.
The aim of the Interdisciplinary Training in Cancer Research training program is to train young scientists to design and conduct research on significant problems in cancer by combining information and approaches from different scientific disciplines, including basic cellular and molecular biology, epidemiology, clinical trials and studies, and behavioral - social sciences.
The study, published in Nature Communications today, focused on protein kinases, enzymes that are key regulators of cellular processes.
The American Journal of Physiology - Heart and Circulatory Physiology focuses on the physiology of the heart, blood vessels and lymphatics, including experimental and theoretical studies of cardiovascular function at all levels of organization ranging from the intact animal to the cellular, subcellular and molecular levels.
Other investigators on this study were Caitlin E. Millett, graduate student, psychiatry and neural and behavioral sciences; Dahlia Mukherjee, postdoctoral fellow, and Aubrey Reider, research assistant, in the Department of Psychiatry, and Shannon L. Kelleher, an associate professor of cellular and molecular physiology, pharmacology, and surgery; Adem Can, University of Maryland School of Medicine; Maureen Groer, University of South Florida, School of Nursing, and Innsbruck Medical University, Austria; Dietmar Fuchs, Innsbruck Medical University, Austria; and Teodor T. Postolache, University of Maryland School of Medicine, Rocky Mountain Mental Illness Research, Education and Clinical Center (MIRECC), and The Military and Veteran Microbiome Consortium for Research and Education, MVM — Core.
Dr. Sonntag studies this concept on the molecular and cellular level using a translational research approach that integrates the analysis of human material, such as postmortem brains, primary cell systems, and neural cell populations generated from patients» - or healthy individuals» - derived induced pluripotent stem cells (iPSC), or induced neurons (iNs), in combination with molecular, biochemistry, and lentivirus - mediated gene - engineering technologies.
Our work focused on Drosophilia, one of the most powerful animal models for studying the cellular and molecular basis of sleep - wake rhythms.
On the one hand, we study systems of proteins that determine cellular fate during spore formation in Bacillus subtilis.
We produce live and inactivated viruses in our BSL2 and BSL3 facilities, and perform immunogenicity and efficacy studies in pigs (influenza) and sheep (RSV) with a focus on skin vaccination and extended monitoring of humoral and cellular immune responses in the blood and lung.
We use neuronal cultures, induced pluripotent stem (iPS) cells and transgenic and gene - targeted mouse models to study the differential effects of apoE3 and apoE4 on cell signaling pathways and cytoskelatal structure and function at molecular, cellular and behavioral levels.
But in a study published April 5 in Cell, Kevan Shokat, PhD, a professor of cellular and molecular pharmacology, and postdoctoral researcher Qi Hu, PhD, discovered that another common cancer - causing mutation in a GTPase called Gαs (or G - alpha - s) subverts the model: it doesn't just jam the switch in the «on» position, but also disconnects the switch entirely.
Various types of meditation have been shown to improve well - being among different populations such as physicians and the general public.14, 15, 16 Preliminary evidence suggests that meditation - based interventions may slow cellular aging rates by increasing telomerase activity, but many such studies lacked an active control group.17, 18 Recent randomized trials in breast cancer suggest that long - term intensive meditation interventions might have positive effects on telomerase activity.
Our work combines computational analysis of high - throughput sequencing data, population genetics, and experimental work.We focus in particular on studying genetic effects on the transcriptome traits, which has further applications in other traits at the cellular and individual level.
In particular, they are focused on studying the functional role and molecular mechanisms of cellular senescence in both of these events, and how a deregulation of normal epithelial stem cell proliferation is involved.
For his 2013 SENS Research Foundation Summer Internship, Ethan joined the laboratory of Dr. Judith Campisi at the Buck Institute for Research on Aging to study cellular senescence, the process by which damaged cells enter irreversible growth arrest.
The Environmental Influences on Health and Disease Group at Sanford Research studies how environmental factors influence cellular function and human disease, an important interface between chemistry, molecular and cell biology, and physiology.
Modern biophysics is a broad and rapidly advancing field encompassing the study of biological structures with a focus on mechanisms at the molecular, cellular, and systems level using the concepts and methods of physics, chemistry, mathematics, engineering, and computational science.
For this reason, the in vivo studies on the human metabolism must be flanked by in vitro and ex-vivo analyses on organ physiology and cellular mechanisms.
These results shed light on how methylation affects motor neuron development and lay the framework for future studies on how methylation dynamics determine cellular fate.