Sentences with phrase «cellular study for»

Highly skilled bioinformatics analyst with strong research history and meticulous attention to detail ready to investigate and manipulate complex material for biological and cellular study for private and government bodies.

Not exact matches

The disruption of prenatal cellular activity in zebra fish, which share 80 percent of their genes with humans and are considered a good model for studying human brain development, seemed to result in hyperactivity, according to the Canadian study, which was published Monday in the Proceedings of the National Academy of Sciences.

Boivin had studied cellular, molecular, and microbial biology for her Bachelor of Science degree at the University of Calgary in her native Canada, but, she says, «I always had an interest in archaeology.»

In conclusion, this new study identifies the cellular origin of Pik3ca - induced tumours and reveals that oncogenic Pik3ca activates a multipotent genetic program, setting the stage for future intratumoural heterogeneity at the earliest stage of tumor development.

So in 1974, he headed south to Tulane University in New Orleans, Louisiana, for graduate training in physiological psychology: the study of how the brain influences behavior at the neurochemical and cellular levels.

Scientists have rolled back time for live mice through systemic cellular reprogramming, according to a study published December 15 in Cell.

Now, in this week's issue of the Proceedings of the National Academy of Sciences, Thomas Albright and Ricardo Gil - da - Costa of the Salk Institute for Biological Studies describe a model system that completes the bridge between cellular and human studies of schizophrenia, an advance that should help speed the development of therapeutics for schizophrenia and other neurological disStudies describe a model system that completes the bridge between cellular and human studies of schizophrenia, an advance that should help speed the development of therapeutics for schizophrenia and other neurological disstudies of schizophrenia, an advance that should help speed the development of therapeutics for schizophrenia and other neurological disorders.

For instance, Dawson says, Autism Speaks is funding studies investigating the idea that disorders in the cellular powerhouses, mitochondria, might influence responses to immune challenges such as infection and immunization.

«Proper blood cell production is dependent on functioning hematopoietic stem and progenitor cells that are destroyed during conditioning procedures for transplantation or following bone marrow injury,» said the study's first author Kevin A. Goncalves, who performed this research as part of his PhD studies in cellular and molecular physiology at the Sackler School.

«Laminins function as attractive chemical cues for haptotaxis of axonal growth cones,» explains NAIST Prof. Naoyuki Inagaki, whose lab studies how forces are generated in the cellular microenvironment to create directed axonal migration.

The study finds no evidence of cellular intestinal inflammation, lactase deficiency, or «leaky gut» specific to autistic children with GI symptoms, according to the new research, led by Timothy Buie, MD, Rafail Kushak, PhD, and Harland Winter, MD, of MassGeneral Hospital for Children, Boston.

Lydia Villa - Komaroff, a molecular and cellular biologist and co-founding member of the Society for the Advancement of Chicanos / Hispanics and Native Americans in Science, underscored the value of basic research, noting that her work studying strains of infection - resistant bacteria led to a discovery that «made it possible to make insulin and other treatments in bacteria.

Dr Christos Gkogkas, a Chancellor's Fellow in the University of Edinburgh's Centre for Discovery Brain Sciences, said: «Our study reveals that altered protein synthesis through eIF4E is a key cellular process in the brain that can go awry in depression.

The cellular functions that Finch studied for his «second Ph.D.» included the activation of the gene that encodes tyrosine aminotransferase (TAT).

«TIA - 1 is known for its ability to regulate gene expression during cellular stress,» says Hewett, who studies the processes that suppress the severe electrical storms in the brain, leading to seizures.

Bruce Buchholz of the Lawrence Livermore National Laboratory used cellular markers for a study in which he concluded that we're more or less stuck with the number of fat cells we have at about age 20.

In order to be able to treat neurodegenerative disorders in future, researcher Ulrich Hartl, Head of the Department of Cellular Biochemistry at the Max Planck Institute of Biochemistry, and his team have for many years been studying the cellular causes for the death of nerve cells.

Their study suggests that EGCG has high potential as a treatment for rheumatoid arthritis because of how effectively the molecule blocks the effects of the disease without blocking other cellular functions.

The researchers hope their new cell lines will be a useful resource for studying the cellular and molecular intricacies of Huntington's further, and suggest they may provide a model for examining other diseases of the brain that are specific to humans.

This study reveals how lipids control SH2 domain - mediated cellular protein interaction networks and suggests a new strategy for the therapeutic modulation of pY - signaling pathways.

The budding yeast, Saccharomyces cerevisiae, is a prime organism for studying fundamental cellular processes, with the functions of many proteins important in the cell cycle and signaling networks found in human biology having first been discovered in yeast.

Additionally, since ribosomal RNA has been shown to have specified controlled of cellular fate, this study provides a theoretical basis for disease therapy and neuroscience research and may lead to future advances in treating degenerative diseases or even brain cancers.

The detailed study of such fundamental cellular processes is crucial for the understanding of diseases that go hand in hand with these events — in the case of autophagy, Alzheimer's disease or cancer.

The study also reports the structural details of the viral gHgLgO complex bound to the cellular PDGFRα, demonstrating that the gO molecule is essential for the binding to PDGFRα and thus represents the key component that triggers the infection of the host.

For efficiently studying cell functions, it is essential to reconstruct cellular microenvironments by parallel manipulation of single cells.

A previous study by Segev at the laboratory for research of molecular and cellular mechanisms, directed by Prof. Kobi Rosenblum in the Sagol Department of Neurobiology at the University of Haifa, found a connection between a genetic condition known to be a risk factor for sporadic Alzheimer's and premature aging as manifested in ongoing metabolic stress.

There he studied the fundamental cellular and biochemical mechanisms required for immune cell activation and clearance of infections.

A number of studies have shown that miRNAs are critical for normal development and cellular growth and may contribute to the complexity of neurodegenerative diseases.

«How male and female sex hormones can affect the immune system is important for understanding the molecular and cellular basis of sex differences in diseases like asthma,» says Nicola Heller, an immunologist at Johns Hopkins University School of Medicine not involved in the study.

Thanks to our new tools for studying human muscle cellular clocks in vitro, we now have the possibility to investigate this hypothesis in our next study.»

«By preventing its normal movement, we essentially turned HIV - 1 into a sitting duck for cellular sensors,» said Edward M. Campbell, PhD, corresponding author of the study, published in the Proceedings of the National Academy of Sciences.

I was extremely enthusiastic about the opportunity to immerse myself in a subject in detail, and chose the mechanisms of cellular immunology to study for a PhD.

Martin Lercher of the University of Bath in England and his colleagues studied a benign strain of Escherichia coli to see how the common intestine dweller picked up new parts for its metabolic network — the internal system of chemical reactions that produce the necessities of life, such as amino acids or cellular structures.

The researchers from the UC Davis Center for Mind and Brain, which studies cognitive brain mechanisms, and Center for Neuroscience, which studies molecular, cellular and system - level brain mechanisms, each brought specific expertise to the collaborative study.

Future work will focus on identifying cellular targets of ampulexins, and potentially generating a useful animal model for the study of Parkinson's disease treatments.

Scientists use it as a model organism for studying cellular signals, disease, and the movement of cells in response to a chemical stimulus (chemotaxis).

NIGMS has awarded $ 5 million a year for 5 years to a group of scientists studying cellular signaling.

Five researchers who study a cellular system for fixing misfolded proteins, deep brain stimulation for Parkinson's disease, and breast cancer genetics have won this year's prestigious Lasker Awards for biomedical research.

Here at the Harvard Brain Tissue Resource Center, donated specimens are sliced up, preserved, stored, and eventually parceled out to neuroscientists worldwide who study them for clues to disease, cognition, and the mysterious cellular underpinnings of psychology.

He said: «Our study has shown for the first time the evidence that local anaesthetic may affect the development of children's teeth in cellular and molecular levels.

Dr. Maria Iribarne, first author of this study, commented: «The gosh mutant is a good model for understanding the molecular and cellular mechanism of cone cell death and the pathological process of human LCA.

Pregnant women who had low socioeconomic status during childhood and who have poor family social support appear to prematurely age on a cellular level, potentially raising the risk for complications, a new study has found.

«Our study shows that the ability of malaria parasites to engage red blood cells is driven by an ancient mechanism for cellular attachment,» said lead author Aditya Paul, a postdoctoral researcher at the Harvard Chan School.

Despite much study of attention in the brain, the cellular mechanisms responsible for the effects of attention have remained a mystery... until now.

«In this study, we identified a novel regulatory factor for the Golgi - ER retrograde transport and a new mechanistic connection between the physiological trafficking and the autophagic transportation of cellular material.»

Further studies will be necessary to identify the preferred cellular attachment and internalization receptors for TMAdV.

Interestingly, isolated islets provide a superior platform for studying propagation of IAPP aggregates because islets retain the composition and organization of endocrine cells and the extracellular matrix, which is absent in isolated, cellular monolayers.

To begin to explore the cellular mechanisms that might be responsible for this response, histological analysis revealed less severe disruption of spermatogenesis and gene expression studies suggested that an interplay of ATP - binding cassette (ABC) efflux transporters and solute carrier (SLC) influx transporters in the testicular cells might be involved.

During those years, the way we study fundamental biological processes underwent a major shift that has now culminated in sequenced human genomes, knowledge of many cellular processes, and a clear path to unraveling roles for individual molecules.

At the Museum of the Rockies we house one of the largest dinosaur collections in the country, and maintain two laboratories, one for the study of cellular and molecular paleontology, and the other for 3 - D imaging utilizing data from CT and 3 - D scanners.