In the second article, Grégory Batt, head of the InBio unit and co-last author with Pascal Hersen (CNRS) of the Laboratoire Matière et systèmes complexes (CNRS / Paris Diderot University), explains how they managed to place
a cellular system in an unstable configuration: «We designed a computer program which aims to force the cells to take binary decisions randomly.
Not exact matches
In the future, the company plans to work with manufacturers and
cellular companies to integrate the technology into more
systems.
Ultimately, what really captures his attention is the Ford Work Solutions, the integrated
in - dash computer
system (4 GB memory with USB and SD ports, plus wireless keyboard and optional Bluetooth - enabled printer) that provides access to a
cellular broadband connection when the engine is on (no worries — you can't use the computer while you're driving).
«What we'll do is make it easy for the
cellular system to be deployed everywhere,» he explains, including hopefully plans to bring high - speed connectivity to schools
in remote parts of developing countries.
Mark, I am an entrepreneur
in need of $ 150,000 to manufacture and market a new innovative
cellular based alarm / security
system for the home & office.
Active fleet tracking
systems, on the other hand, connects to a satellite or
cellular network and transmits all that data while the vehicle is
in transit.
Given a
system or composite of individuals, all on a comparable level, for instance molecular or
cellular, then
in some cases, given integration of activities (thus molecules
in a cell, or cells
in a vertebrate animal), there may be what Leibniz called a «dominant monad» or what Whitehead calls a «society of presiding occasions.»
In the above article the words:
cellular, hormones, brain and nervous
system appear by the second paragraph with absolutely no references to explain how these biological terms or processes relate to birth or birth trauma.
Some autopsy data shows that infants of smokers have signs of established hypoxic - ischemic
cellular injury
in the brain and the heart which probably occurred
in antenatal life, may have been caused by suboptimal placental function and may have been sub-clinical, but if the baby continues to be
in a vulnerable environment exposed to post-natal passive smoking, this could affect autonomic nervous
system function and lead to poor temperature control, and poor heart rate and respiration control.
Cuomo told the MTA to hold a «Genius Award» contest to find the best ideas on how to overcome the seemingly unfixable subway problems of the ancient signal
system, the aging fleet of cars, and the lack of
cellular and wi - fi connections on trains and
in tunnels.
To help make ideas about energy more concrete, for example, the new unit will use a variety of analogies from more familiar physical
systems (e.g., combustion and charging a cellphone battery) to help students understand those same energy - releasing and energy - requiring chemical reactions and energy transfer when they occur
in living organisms (e.g.,
cellular respiration, creating a charge across a membrane
in mitochondria and nerve cells) where the reactions are more complex and difficult to observe.
Thus, light - sheet
systems have become the next wave
in live - cell imaging for many scientists interested
in high - speed
cellular activities, such as the firing of neurons or the flowing of blood cells.
The researchers found that the immune cells
in the skin of this animal model generated large amounts of the cytokine IL - 17 — a protein of the immune
system that activates
cellular inflammation
in response to damage.
Now, the research team discovered that the disruption of the
cellular proteins pICln and Tgs1, two chief players that help assemble the splicing machinery, causes the fruit flies» neuromuscular
system to collapse
in a similar manner to patients with SMA.
In effect, PD - 1 may actually help to preserve a «reserve force» of T cells that can fight on later in the long - term cellular war between the immune system and foreign invaders or tumor
In effect, PD - 1 may actually help to preserve a «reserve force» of T cells that can fight on later
in the long - term cellular war between the immune system and foreign invaders or tumor
in the long - term
cellular war between the immune
system and foreign invaders or tumors.
«
In contrast to RNA interference, which is commonly used to inactivate gene activity, the CRISPR - on
system allows activation of
cellular genes.
Now,
in this week's issue of the Proceedings of the National Academy of Sciences, Thomas Albright and Ricardo Gil - da - Costa of the Salk Institute for Biological Studies describe a model
system that completes the bridge between
cellular and human studies of schizophrenia, an advance that should help speed the development of therapeutics for schizophrenia and other neurological disorders.
Autophagy literally means «self - eating,» and refers to a sophisticated
system in which
cellular waste is specifically detected, surrounded by membranes, and removed.
This interaction activates MALT1 to cleave and inactivate a number of
cellular proteins that normally keep the immune
system in check.
The researchers reported the natural inflammatory response when a foreign substance like a hydrogel is introduced into a
system and draws cells that secrete proteins involved
in cellular infiltration, scaffold degradation, vascularization and innervation.
This discovery lends more weight to the growing evidence that inflammation — and our immune
system's hyperactive reaction
in mopping up the
cellular debris left by the wayward plaques and tangles — plays a key role
in the spread of the disease.
With Gazzaley's background
in cellular and
systems neurobiology, «Adam's going to bring a lot of that expertise to his imaging studies,» Morrison says, and is well - positioned to make important contributions.
Using cell - based model
systems and Drosophila, they found CRMP1 overexpression reduces hungtingtin aggregation and
cellular toxicity, while reduced CRMP1 results
in increased aggregation and toxicity.
In the latest experiments the Mitalipov group focused on snipping out the mutated gene in heterozygous cells — a situation in which there was still a «good» nonmutated copy available for the natural cellular repair systems in the embryo to use as a template for repair after the researchers edited out the problematic on
In the latest experiments the Mitalipov group focused on snipping out the mutated gene
in heterozygous cells — a situation in which there was still a «good» nonmutated copy available for the natural cellular repair systems in the embryo to use as a template for repair after the researchers edited out the problematic on
in heterozygous cells — a situation
in which there was still a «good» nonmutated copy available for the natural cellular repair systems in the embryo to use as a template for repair after the researchers edited out the problematic on
in which there was still a «good» nonmutated copy available for the natural
cellular repair
systems in the embryo to use as a template for repair after the researchers edited out the problematic on
in the embryo to use as a template for repair after the researchers edited out the problematic one.
«If we can find molecules that modulate membralin, or identify its role
in the
cellular protein disposal machinery known as the endoplasmic reticulum - associated degradation (ERAD)
system, this may put the brakes on neurodegeneration.»
«Immune
system found to control eye tissue renewal
in zebrafish: Discovery suggests that strategies to regulate immune
system cell reactivity to injury and cell loss might one day unlock and boost human tissue and
cellular regeneration.»
The investigators suggest that the premature loss of estrogen caused by the oophorectomy may affect a series of aging mechanisms at the
cellular and tissue level across the whole body leading to diseases
in multiple
systems and organs.
His research group focuses on big data network biology, exploring biological
systems by developing and deploying algorithms aimed to predict cell behavior,
in particular looking at
cellular signal processing and decision making.
His pioneering research has focused on defining the
cellular and molecular nature of immune exhaustion — the failure of normal immune
system function —
in chronic infection and cancer.
Previous studies
in the lab showed that once HCMV is inside the cell, it quickly becomes latent by entering the cell's nucleus and co-opting a
cellular protein called Daxx — part of the intrinsic immune
system — to shut down its own replication, the process of reproducing its genetic material to make more copies of itself.
«It was crucial to establish a
cellular system with similar characteristics of the affected nerve cells
in the patients,» Prigione says.
In an attempt to protect the body from the spreading virus, these immune cells then commit «
cellular suicide,» leading to the collapse of the immune
system — and AIDS.
«This technology could have very important applications
in ultra-high-speed links for the wireless «backhaul» that connects base stations of next - generation
cellular systems,» said Andy Molisch of USC Viterbi.
What scientists once thought was unremarkable
cellular «noise»
in neuron signaling has come to be viewed as important to overall
system - wide functioning
in the brain.
Think of the army of
cellular agents, including white blood cells and platelets, that jump into action over a mere paper cut — rebuilding the tissue, warding off infection, and alerting the rest of the body to the wound through the A-delta fibers of the nervous
system, which are involved
in the transmission of acute pain sensations.
A unique feature of this DREADD
system not found
in other methods is that it is not limited to the control of neurons — activity levels of certain enzymes
in almost every tissue type can be controlled to probe mechanisms of basic
cellular function.
«How male and female sex hormones can affect the immune
system is important for understanding the molecular and
cellular basis of sex differences
in diseases like asthma,» says Nicola Heller, an immunologist at Johns Hopkins University School of Medicine not involved
in the study.
Martin Lercher of the University of Bath
in England and his colleagues studied a benign strain of Escherichia coli to see how the common intestine dweller picked up new parts for its metabolic network — the internal
system of chemical reactions that produce the necessities of life, such as amino acids or
cellular structures.
Systems biology provides better methods of drug discovery: research teams can measure changes
in genetic activity, protein levels and
cellular behavior of the immune
system in response to a potential vaccine.
More recently, similar RNA molecules have been identified
in cellular systems, though the sequences tend to be much shorter and function
in a different manner.
Although logic would dictate that the smaller the particle, the more likely it is to infiltrate a
cellular membrane, the researchers found that rodlike particles are able to get
in faster than other shapes because of how the immune
system responds to them.
To gain an understanding of the mechanism that connects low mtDNA levels with a
cellular change that leads to cancer and metastasis, Guha, Avadhani and their colleagues set up two
systems by which they could purposefully reduce the amount of mtDNA
in a cell.
Wolfram syndrome is caused by a mutation
in the gene encoding a protein called wolframin, which resides
in the membrane of the endoplasmic reticulum — another
cellular compartment that functions as a manufacturing and packaging
system and also acts as a reservoir for calcium ions.
«We now have a tool to control temperature on a
cellular level, and we can study how biological
systems react to temperature change,» says Peter Maurer, a physicist at Harvard University
in Cambridge, Massachusetts, and a member of the team publishing the result today
in Nature.
The new
system allowed the team to add a third residue — lysine 33 — to ubiquitin's repertoire
in controlling this
cellular housekeeping
system.
Now researchers have devised a way to trick one of the gatekeepers
in this
cellular defense
system into escorting a potentially beneficial antibody into the brain.
By administering Zika virus directly into the reproductive tract of pregnant mice that have an intact immune
system, the researchers found that the Zika virus appears to create disorganization
in the
cellular layers of the placenta that keep toxins, bacteria and viruses from crossing.
Scientists from The Scripps Research Institute (TSRI), working closely with researchers at the National Institutes of Health (NIH), have mapped out the structure of an important protein involved
in cellular function and nervous
system development.
Together with her colleagues Margaret MacGibeny, an M.D. / Ph.D. student, then - postdoctoral researcher Ian Hogue, and Lynn Enquist, the lab's principal investigator and the Henry L. Hillman Professor
in Molecular Biology, Koyuncu has used this unique latency model
system to reveal specific
cellular and viral components that can prevent the infection from going to sleep.
To achieve such integration, Tara Oceans is driven by researchers with expertise
in biological and physical oceanography, ecology, microbiology, systematics, molecular,
cellular and
systems biology, bioinformatics, data management, and modeling.