Sentences with phrase «cellular therapy»

It is poised to become a major site for research and early development of personalized cellular therapies for cancer.

And there have been developments in cellular therapies to treat cancer, with two treatments aiming for approval by the end of 2017.

Our group is studying the use of various cell and stem cell populations for application in new cellular therapies.

The accessibility of the retina, together with imaging technologies makes it a prime candidate for developing cellular therapies for central nervous disorders.

A personalized cellular therapy, it teaches the body's immune systems to recognize and kill cancer cells.

Human ES cells may become the basis for far - reaching progress in cellular therapy.

The routine use of MSC cellular therapy with would benefit from a uniform cell source, with stable phenotype and function as well as providing a solution to potential safety issues.

«New liver cell for cellular therapy to aid in liver regeneration.»

Black Beret Life Sciences is also actively working to expedite FDA approval of safe and effective cellular therapies in the U.S..

Combining the kinase inhibitor ibrutinib with an investigational personalized cellular therapy known as CTL119 can lead to complete remission in patients with high - risk chronic lymphocytic leukemia (CLL), according to new research from the Perelman School of Medicine at the University of Pennsylvania and Penn's Abramson Cancer Center (ACC).

Novocell has developed and proven methods to efficiently generate pancreatic, insulin - producing cells from hESCs, demonstrating for the first time that hESCs could serve as a source of cellular therapy for diabetes.

Established in 1992, ISCT is a global society of clinicians, researchers, regulators, technologists and industry partners with a shared vision to translate cellular therapy into safe and effective therapies to improve patients» lives worldwide.

The objectives of our group are to develop pre-clinical studies required for the development of human pluripotent stem cells cellular therapy for the treatment of a number of retinal diseases.

This is the first time that that this assay has been used to ascertain retinal function after cellular therapy in a retinal degenerate animal.

Dendreon was first - to - market with its activated cellular therapy, Provenge ® in 2010 followed by a 7 year gap until Novartis» Kymriah ® was approved in August of 2017 which was shortly followed up by the approval of Kite Pharma's Yescata ® in November of 2017.

Perhaps cellular therapy, such as mesenchymal stem cells, will be an important advance in the care of these fragile infants.

While her postdoc work is not related directly to cystinosis, she hopes there are aspects of the gene therapy and cellular therapy skills she is learning at Scripps that will be transferable to her work with the disease.

«Personalized cellular therapy achieves complete remission in 90 percent of acute lymphoblastic leukemia patients studied.»

Today a world force in the field of regenerative medicine, he's close to delivering cellular therapies that might reseed the immune system, heal damaged hearts, even save limbs.

With cellular therapy holding enormous promise for future cures and treatments, Black Beret Life Sciences is committed to doing what it can to help the field reach its full medical potential by creating a more efficient regulatory framework in the U.S.

The report, which included a recommendation on advancing regenerative cellular therapies, proposed a series of viable legislative actions that Congress could take to help streamline the process by which safe and effective medical products are developed and delivered to patients.

Our research is located at the interface of immunology and stem cell research and our recent findings lay the groundwork for new cellular therapy approaches in regenerative medicine.

AFM supports each year more than 400 research programs, among them more than 30 clinical trials in gene therapy or cellular therapy concerning for example muscular, eyes, skin or blood diseases.

Back in November 2017, the FDA announced a comprehensive policy framework for the development and oversight of regenerative medicine products, including novel cellular therapies.

In 2016, the Food and Drug Administration (FDA), the branch of government charged with regulating cellular therapies, took action to address these issues, proposing revised guidelines that could change how stem cells, especially autologous stem cells, are regulated.

New molecular biology technologies — e.g., improved lenti - and adenoviral vectors, gene editing tools such as zinc - finger nucleases and the CRISPR / Cas9 platform — have opened doors to the development of novel gene - modified cellular therapies.

Consequently, they hold great potential in the medical field for treating a wide variety of diseases; researchers can make the hESCs become a desired cell type and use these in transplants or other cellular therapies.

Therefore, this work provides strong support for the use of iPSC ‐ derived MSC as a more uniform with well ‐ defined phenotype and function as a sustainable source of cells which paves the way for a clinical application for IBD cellular therapy.

The focus of the Muench laboratory is on cellular therapies, transfusion and models of infectious disease.

The funding will advance Novocell's development of a first in kind cellular therapy for the treatment of diabetes.

These findings have identified an alternative source of replacement tissue for use in human retinal cellular therapies, and provide a new in vitro cellular model system in which to study RPE diseases affecting human patients.

Dr. Bosarge was also actively involved in an effort to streamline FDA approval of safe and effective cellular therapies in the U.S., recently leading a federal legislative initiative in partnership with the Bipartisan Policy Center.

A multiple myeloma patient whose cancer had stopped responding after nine different treatment regimens experienced a complete remission after receiving an investigational personalized cellular therapy known as CTL019 developed by a team at the University of Pennsylvania.

We're also developing cellular therapies, which improve the canker - killing activity of powerful immune cells called NK cells and T cells, rather than using drugs to treat the cancer directly.

PHILADELPHIA — A multiple myeloma patient whose cancer had stopped responding after nine different treatment regimens experienced a complete remission after receiving an investigational personalized cellular therapy known as CTL019 developed by a team at the University of Pennsylvania.

A new cellular therapy could change that.

To meet this end, CCIR members take advantage of resources offered by MD Anderson, including the CCSG Shared Resources, Immune Monitoring Core Laboratory and GMP Cell Facility, allowing them to follow the «bench - to - beside» approach to develop and improve cancer immunotherapy in the form of cellular therapy, a vaccine or targeting antibody, either alone or in combination with conventional therapies or newly developed therapies.

«In contrast,» says Hopkins radiology professor Jeff Bulte, Ph.D., «MRI is noninvasive, allowing serial imaging of cells and cellular therapies with a high resolution unmatched by any other clinical whole - body imaging technique.»

«Engineers grow functioning human muscle from skin cells: First functioning human muscle grown from induced pluripotent stem cells holds promise for cellular therapies, drug discovery and studying rare diseases.»

«One of the challenges in treating CLL patients with personalized cellular therapy is not having healthy enough cells to manufacture.

The ability to start from cellular scratch using non-muscle tissue will allow scientists to grow far more muscle cells, provide an easier path to genome editing and cellular therapies, and develop individually tailored models of rare muscle diseases for drug discovery and basic biology studies.

«They are impaired in disease, and effective cellular therapies should target not only other retinal cell types but these cells as well.»

Celgene's pipeline includes several oral drugs for solid tumors and hematologic cancers and cellular therapies for Crohn's disease, multiple sclerosis, rheumatoid arthritis, and sarcoidosis.

Dr. Owen Witte, Director of the UCLA Broad Stem Cell Research Center, highlighted that the «The CIRM support demonstrates that our multidisciplinary Center is at the forefront of translating basic scientific research to new drug and cellular therapies that will revolutionize medicine.»

CTL019 is the first personalized cellular therapy to receive the designation.

«Sustained remission of multiple myeloma after personalized cellular therapy: New treatment combination with CTL019 targets precursors of cancerous white blood cells.»

Ninety percent of children and adults with acute lymphoblastic leukemia (ALL) who had relapsed multiple times or failed to respond to standard therapies went into remission after receiving an investigational personalized cellular therapy, CTL019, developed at the Perelman School of Medicine at the University of Pennsylvania.

More precise dosing methods and cellular engineering techniques show promise in the effort to improve treatment of aggressive cancers with personalized cellular therapies, according to new studies from researchers in the Perelman School of Medicine and the Abramson Cancer Center at the University of Pennsylvania and The Children's Hospital of Philadelphia.

The composition of bacteria in the gastrointestinal tract may hold clues to help predict which cancer patients are most apt to benefit from the personalized cellular therapies that have shown unprecedented promise in the fight against hard - to - treat cancers, according to new research from the Perelman School of Medicine at the University of Pennsylvania.