Sentences with phrase «cellular toxicity»

"Cellular toxicity" refers to when harmful substances or conditions cause damage or destruction to our body's cells. It can lead to a range of negative effects on our health. Full definition
We propose by specifically targeting virus - virus interactions to find drugs with low cellular toxicity.
They measured cellular toxicity of 156 compounds on these cell lines, which represented individuals from nine subpopulations throughout Europe, Africa, Asia and the Americas.
Certain types of misfolded proteins defy eradication by the cellular protein degradation machinery and accumulate with age, causing cellular toxicity.
The authors demonstrated that these compounds inhibit the transport of a broad range of key MRP4 substrates, and that they are low in cellular toxicity and highly stable.
Significant reduction in H3K9 dimethylation at 100nM in MDA - MB231 cells as measured by fluorescence immunostaining without significant cellular toxicity.
«In both models, we found that neither IBs nor kinase activity were the direct causes of cellular toxicity leading to neuronal death,» said Dr. Skibinski, who was the paper's lead author.
Either way, many researchers believe that carnosine supplementation will reduce disease - causing cellular toxicity and possibly help to prevent Alzheimer's and Parkinson's diseases.
Using cell - based model systems and Drosophila, they found CRMP1 overexpression reduces hungtingtin aggregation and cellular toxicity, while reduced CRMP1 results in increased aggregation and toxicity.
This property will enable the use of UNC0638 without concern about possible complications of cellular toxicity.
Emerging evidence indicates that compromised autophagy contributes to the aetiology of various neurodegenerative diseases related to protein conformational disorders by causing the accumulation of mutant proteins and cellular toxicity.
Scientists at the Institute of Medical Science and Jeju National University in Korea found the asparagus extracts «significantly alleviated» the cellular toxicity of alcohol, a benefit that translates to lessening of a hangover and protection of liver cells.
New studies, by the way, are showing that cellular toxicity can trigger certain disease states within the body, (which means to turn on our gene expression) of which diabetes is one of these diseases.
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