Insulin assists with
cellular uptake of glucose from the bloodstream into the cells of the body for energy.
Glutamine both stimulates mTOR directly through the ARF1 pathway and indirectly by regulating
cellular uptake of leucine to stimulate mTOR through the RAG pathway.
Insulin functions include: Lowering blood glucose Promoting
cellular uptake of carbohydrates, amino acids and fatty acids Promoting fat storage (when at excessive levels) Insulin is a powerful anabolic hormone because it moves amino acids into muscle cells.
Nevertheless, little is still known about the influence of carbohydrates on the toxicity and
cellular uptake of nanoparticles.
Here, we discuss the toxicity and
the cellular uptake of different silver nanoparticles functionalized with citrate, three different monosaccharides as well as ethylene glycol on two different cell lines.
9:45 — 10:15 Filippo Mancia (Columbia Uni) The molecular mechanisms underlying
cellular uptake of vitamin A
Apart from the various biomedical applications of nanomaterials, especially in cancer therapy,
cellular uptake of nanoparticles is a key factor in recent years for efficient drug delivery applications.
For instance, three scavenger receptor genes were suggested to facilitate
the cellular uptake of carotenoids in the adductor muscles of orange - adductor Yesso scallop [13].
The team demonstrated that cell sex considerably influenced
cellular uptake of nanoparticles and found that cells from men and women responded differently to reprogramming techniques used to enhance the ability of the cells to differentiate into a greater variety of cell types.
Not exact matches
«By offering the distinct advantage
of subcellular resolution and avoiding the undesirable influence
of fluorescent dyes, we believe our technique can complement FDG in clinical PET imaging for visualizing glucose
uptake activity at the
cellular level,» says the lead author Fanghao Hu, a Ph.D. candidate in chemistry.
Due to the major importance
of iron in a wide variety
of cellular processes, and the harm caused by its uncontrolled accumulation in the body, its
uptake and storage is strictly regulated.
«While nanoparticle shape has been shown to impact
cellular uptake, the latest study shows that specific tissues can be targeted by controlling the shape
of nanoparticles.
After graduating, Clara moved to the UK to work as a Research fellow with Prof John Findlay at the University
of Leeds, working mainly with Lipocalins and their
cellular receptors, identifying structural binding / transport motifs and investigating the physiological link between vitamin A
uptake and Type 2 Diabetes.
«That issue starts at the
cellular - molecular level, with the actual testing and the understanding that biologists have
of the pathology
of colorectal cancer and diagnosis
of colorectal cancer, all the way to the community
uptake of that screening.»
Functionalisation
of silver nanoparticles with monosaccharides modulates their
cellular uptake and toxicity.
Quantitative evaluation
of cellular uptake and trafficking
of plain and polyethylene glycol - coated gold nanoparticles.
A second set
of cellular level events involves
uptake of iodine into thyroid cells by a protein referred to as the sodium - iodide symporter (and abbreviated as «NIS,» where the «N» comes from «Na,» which is the scientific abbreviation for the element sodium).
A person may feel unwell initially on this type
of diet but the all important
uptake of potassium will slowly improve at the
cellular level.
Twelve - hour exposure
of 3T3 - L1 adipocytes to H (2) O (2) or TNF - alpha resulted in the increase
of c - Jun NH (2)- terminal kinase (JNK) activation and insulin receptor substrate 1 (IRS1) serine 307 phosphorylation, concomitantly with the decrease in insulin - stimulated IRS1 tyrosine phosphorylation and
cellular glucose
uptake.
PEMF uses electrical energy to direct a series
of magnetic pulses through injured tissue, and each magnetic pulse induces a tiny electrical signal that stimulates
cellular repair by upregulating a tissue repair protein called «heat shock protein» and also by increasing the
uptake of oxygen and nutrients into tissue.
The rapid repetitive contractions occur all the way down to the
cellular level, causing a more permeable
cellular wall allowing increased
uptake of oxygen and nutrients.
Insulin promotes the efficient storage and use
of glucose molecules by controlling their transport across cell membranes, permitting
cellular uptake and metabolism
of glucose.