Sentences with phrase «central hyperexcitability»
Previous research has shown that people with cWAD can be more sensitive to pain, through an effect called central hyperexcitability.
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«Essentially, they cause acetylcholine to build up in the brain, causing hyperexcitability of neurons as well as the death of some neurons, which leads to inflammation in the brain,» said Ashok K. Shetty, PhD, a professor in the Department of Molecular and Cellular Medicine at the Texas A&M College of Medicine, associate director of the Institute for Regenerative Medicine, research career scientist at the Olin E. Teague Veterans Medical Center, Central Texas Veterans Health Care System and senior author of the paper.
AMANTADINE This drug acts to modulate the pain response by antagonizing the N - methyl - d - aspartate (NMDA) receptor and the role they play in central neuronal hyperexcitability (wind up).