Sentences with phrase «central memory t»

Extensive replicative capacity of human central memory T cells.

After the infection, cell numbers diminish, but central memory T cells retain a long - term ability to defend against reinfection by microorganisms that carry the same antigen.

«Previously it was thought that HIV was hiding primarily in central memory T - cells, but our new HIV genetic sequencing test has revealed that the majority of replication - competent virus is actually hiding in effector memory T - cells.

Not exact matches

Single - cell differential gene expression analysis revealed a spectrum of known transcripts, including several linked to cytotoxic and costimulatory function that are expressed at higher levels in the TEMRA (effector memory T cells expressing CD45RA) subset, which is highly enriched for CD4 - CTLs, compared with CD4 + T cells in the central memory (TCM) and effector memory (TEM) subsets.

The phenotype of NP cells generated ex vivo (Figure S8) closely resembles that of central memory CD4 + T cells found in vivo, which persist for years in secondary lymphoid organs and can differentiate into effector memory CD4 + T cells [45].

Elite controllers with low to absent effector CD8 + T cell responses maintain highly functional, broadly directed central memory responses.

CD8 T cells specific for the noninflationary M45 epitope displayed a classic central memory phenotype, re-expressing the lymph node homing receptor CD62L and homeostatic cytokine receptors for IL - 7 and IL - 15, and produced low levels of IL - 2.

ABS,4 - Wheel Disc Brakes,5 - Speed A / T, 8 Cylinder Engine, A / C, A / T, Active Suspension, Adjustable Steering Wheel, Air Suspension, Security System, All Wheel Drive, Aluminum Wheels, AM / FM Stereo, Transmission w / Dual Shift Mode, Automatic Headlights, Brake Assist, Bucket Seats, CD Player, Climate Control, Cruise Control, Daytime Running Lights, Driver Air Bag, Driver Illuminated Vanity Mirror, Driver Adjustable Lumbar, Driver Vanity Mirror,Multi - Zone A / C, Auto - Dimming Rearview Mirror, Fog Lamps, Floor Mats, Front Reading Lamps, Gasoline Fuel, Heated Front Seat (s), Heated Mirrors, HID headlights, Intermittent Wipers, Keyless Entry, Leather Seats, Leather Steering Wheel, Mirror Memory, Navigation System, Telematics, Passenger Air Bag, Passenger Illuminated Visor Mirror, Passenger Adjustable Lumbar, Passenger Vanity Mirror, Power Door Locks, Power Mirror (s), Power Driver Seat, Power Folding Mirrors, Power Passenger Seat, Power Steering, Sun / Moonroof, Power Windows, Premium Sound System, Rain Sensing Wipers, Rear Side Air Bag, Rear Defrost, Rear Head Air Bag, Rear Reading Lamps, Seat Memory, Front Side Air Bag, Front Head Air Bag, Steering Wheel Audio Controls, Sun / Moon Roof, Tires - Front Performance, Tires - Rear Performance, Traction Control, Trip Computer, Universal Garage Door Opener, Variable Speed Intermittent Wipers, Engine Immobilizer, Woodgrain Interior Trim, Door / trunk closing assist feature, Driver programmable daytime running headlamps,Driver - selectable auto on Bi-Xenon high intensity discharge headlamps w / auto level control, heated washers, Halogen front fog lamps, Infared reflective glass, Pwr folding heated memory side mirrors w / auto - dimming left - side mirror, park assist right - side mirror, Pwr tilt / sliding tinted glass sunroof w / one - touch express open / close & memory,Rain - sensing wipers w / heated washer system, heated wiper parking position, Single red rear fog lamp, (4) illuminated vanity mirrors,14 - way pwr heated adjustable memory front bucket seats w / pneumatically adjustable lumbar support, AM / FM / weatherband stereo w / CD, CD changer controls,Anti - theft alarm system w / tow - away protection, remote panic feature, auto notification via Tele Aid,Auto - dimming memory rearview mirror, Bose sound system - inc: (10) speakers, Bose Audio Pilot digital processing, Carpeted floor mats, Cruise control, Dual zone auto climate control - inc: vents in rear of console, individual left / right temp controls, rest mode, charcoal filter, humidity sensor, Front center armrest w / illuminated climate - controlled storage, retractable cupholders, Front seatback magazine pockets,Gauges - inc: electro - luminescent analog speedometer, tachometer, fuel & coolant, GPS / CD - ROM based navigation system, Hand polished burl walnut wood trim - inc: dash, console, doors, shift gate, HomeLink compatible 3 - button garage door control, Leather trimmed shift knob,Lighting - inc: front Xenon reading lamps, rear reading lamps, courtesy lamps w / programmable fade - out time, Multifunction display in speedometer face - inc: odometer, trip meter / computer, flexible service system, oil level, digital speed readout, radio / CD / phone status, Multifunction steering wheel - inc: audio, phone, climate & multifunction display controls, Nappa leather seating surfaces, Premium leather upholstery - inc: head restraints, center armrests, door trim inserts, Pwr rear window sunshade w / one - touch express up / down, Pwr tilt / telescopic leather trimmed steering wheel w / easy exit & memory features, Pwr windows w / one - touch express up / down for all windows, Rear center armrest w / retractable cupholders, Rear window defroster w / auto shutoff, Smartkey system - inc: selectively remote central unlock / locking system, engine disabling security feature, outside control of windows / sunroof, Tele Aid GPS system - inc: 24 hr cellular link to provide emergency aid, information & roadside assistance, automatic collision / alarm notification, stolen vehicle tracking, remote keyless unlocking services, 17 x 7.5 7 - spoke aluminum - alloy wheels,4 - wheel electronic traction system (4 - ETS), 5 - speed automatic transmission w / touch shift & 2nd gear start, 5.0 L SOHC SMPI 24 - valve aluminum - alloy V8 engine, Airmatic air suspension w / adaptive damping system, All wheel drive,Anti - lock braking system (ABS), Brake assist system (applies full braking pwr automatically when needed), Cross-drilled vented front / rear disc brakes w / front Brembo 4 - piston calipers, rear 2 - piston calipers, Electronic brake force distribution, Independent 4 - link front suspension w / anti-dive geometry, Independent 5 - link rear suspension w / anti-dive geometry, P225 / 55HR17 all - season performance SBR tires,Speed - sensitive pwr rack & pinion steering,3 - point seat belts for all seating positions,Anti - lock braking system (ABS), Driver programmable daytime running headlamps, Driver / front passenger front air bag, Head curtain air bag for all outboard seating positions, LATCH universal tethers / anchors for rear outboard seating positions,PRE - SAFE feature (Helps prepare occupants for a possible collision by tightening front seat belts, adjusts all pwr seats & if a possible rollover occurs, will close sunroof), Side - impact body protection air bag for all outboard seating posMemory, Navigation System, Telematics, Passenger Air Bag, Passenger Illuminated Visor Mirror, Passenger Adjustable Lumbar, Passenger Vanity Mirror, Power Door Locks, Power Mirror (s), Power Driver Seat, Power Folding Mirrors, Power Passenger Seat, Power Steering, Sun / Moonroof, Power Windows, Premium Sound System, Rain Sensing Wipers, Rear Side Air Bag, Rear Defrost, Rear Head Air Bag, Rear Reading Lamps, Seat Memory, Front Side Air Bag, Front Head Air Bag, Steering Wheel Audio Controls, Sun / Moon Roof, Tires - Front Performance, Tires - Rear Performance, Traction Control, Trip Computer, Universal Garage Door Opener, Variable Speed Intermittent Wipers, Engine Immobilizer, Woodgrain Interior Trim, Door / trunk closing assist feature, Driver programmable daytime running headlamps,Driver - selectable auto on Bi-Xenon high intensity discharge headlamps w / auto level control, heated washers, Halogen front fog lamps, Infared reflective glass, Pwr folding heated memory side mirrors w / auto - dimming left - side mirror, park assist right - side mirror, Pwr tilt / sliding tinted glass sunroof w / one - touch express open / close & memory,Rain - sensing wipers w / heated washer system, heated wiper parking position, Single red rear fog lamp, (4) illuminated vanity mirrors,14 - way pwr heated adjustable memory front bucket seats w / pneumatically adjustable lumbar support, AM / FM / weatherband stereo w / CD, CD changer controls,Anti - theft alarm system w / tow - away protection, remote panic feature, auto notification via Tele Aid,Auto - dimming memory rearview mirror, Bose sound system - inc: (10) speakers, Bose Audio Pilot digital processing, Carpeted floor mats, Cruise control, Dual zone auto climate control - inc: vents in rear of console, individual left / right temp controls, rest mode, charcoal filter, humidity sensor, Front center armrest w / illuminated climate - controlled storage, retractable cupholders, Front seatback magazine pockets,Gauges - inc: electro - luminescent analog speedometer, tachometer, fuel & coolant, GPS / CD - ROM based navigation system, Hand polished burl walnut wood trim - inc: dash, console, doors, shift gate, HomeLink compatible 3 - button garage door control, Leather trimmed shift knob,Lighting - inc: front Xenon reading lamps, rear reading lamps, courtesy lamps w / programmable fade - out time, Multifunction display in speedometer face - inc: odometer, trip meter / computer, flexible service system, oil level, digital speed readout, radio / CD / phone status, Multifunction steering wheel - inc: audio, phone, climate & multifunction display controls, Nappa leather seating surfaces, Premium leather upholstery - inc: head restraints, center armrests, door trim inserts, Pwr rear window sunshade w / one - touch express up / down, Pwr tilt / telescopic leather trimmed steering wheel w / easy exit & memory features, Pwr windows w / one - touch express up / down for all windows, Rear center armrest w / retractable cupholders, Rear window defroster w / auto shutoff, Smartkey system - inc: selectively remote central unlock / locking system, engine disabling security feature, outside control of windows / sunroof, Tele Aid GPS system - inc: 24 hr cellular link to provide emergency aid, information & roadside assistance, automatic collision / alarm notification, stolen vehicle tracking, remote keyless unlocking services, 17 x 7.5 7 - spoke aluminum - alloy wheels,4 - wheel electronic traction system (4 - ETS), 5 - speed automatic transmission w / touch shift & 2nd gear start, 5.0 L SOHC SMPI 24 - valve aluminum - alloy V8 engine, Airmatic air suspension w / adaptive damping system, All wheel drive,Anti - lock braking system (ABS), Brake assist system (applies full braking pwr automatically when needed), Cross-drilled vented front / rear disc brakes w / front Brembo 4 - piston calipers, rear 2 - piston calipers, Electronic brake force distribution, Independent 4 - link front suspension w / anti-dive geometry, Independent 5 - link rear suspension w / anti-dive geometry, P225 / 55HR17 all - season performance SBR tires,Speed - sensitive pwr rack & pinion steering,3 - point seat belts for all seating positions,Anti - lock braking system (ABS), Driver programmable daytime running headlamps, Driver / front passenger front air bag, Head curtain air bag for all outboard seating positions, LATCH universal tethers / anchors for rear outboard seating positions,PRE - SAFE feature (Helps prepare occupants for a possible collision by tightening front seat belts, adjusts all pwr seats & if a possible rollover occurs, will close sunroof), Side - impact body protection air bag for all outboard seating posMemory, Front Side Air Bag, Front Head Air Bag, Steering Wheel Audio Controls, Sun / Moon Roof, Tires - Front Performance, Tires - Rear Performance, Traction Control, Trip Computer, Universal Garage Door Opener, Variable Speed Intermittent Wipers, Engine Immobilizer, Woodgrain Interior Trim, Door / trunk closing assist feature, Driver programmable daytime running headlamps,Driver - selectable auto on Bi-Xenon high intensity discharge headlamps w / auto level control, heated washers, Halogen front fog lamps, Infared reflective glass, Pwr folding heated memory side mirrors w / auto - dimming left - side mirror, park assist right - side mirror, Pwr tilt / sliding tinted glass sunroof w / one - touch express open / close & memory,Rain - sensing wipers w / heated washer system, heated wiper parking position, Single red rear fog lamp, (4) illuminated vanity mirrors,14 - way pwr heated adjustable memory front bucket seats w / pneumatically adjustable lumbar support, AM / FM / weatherband stereo w / CD, CD changer controls,Anti - theft alarm system w / tow - away protection, remote panic feature, auto notification via Tele Aid,Auto - dimming memory rearview mirror, Bose sound system - inc: (10) speakers, Bose Audio Pilot digital processing, Carpeted floor mats, Cruise control, Dual zone auto climate control - inc: vents in rear of console, individual left / right temp controls, rest mode, charcoal filter, humidity sensor, Front center armrest w / illuminated climate - controlled storage, retractable cupholders, Front seatback magazine pockets,Gauges - inc: electro - luminescent analog speedometer, tachometer, fuel & coolant, GPS / CD - ROM based navigation system, Hand polished burl walnut wood trim - inc: dash, console, doors, shift gate, HomeLink compatible 3 - button garage door control, Leather trimmed shift knob,Lighting - inc: front Xenon reading lamps, rear reading lamps, courtesy lamps w / programmable fade - out time, Multifunction display in speedometer face - inc: odometer, trip meter / computer, flexible service system, oil level, digital speed readout, radio / CD / phone status, Multifunction steering wheel - inc: audio, phone, climate & multifunction display controls, Nappa leather seating surfaces, Premium leather upholstery - inc: head restraints, center armrests, door trim inserts, Pwr rear window sunshade w / one - touch express up / down, Pwr tilt / telescopic leather trimmed steering wheel w / easy exit & memory features, Pwr windows w / one - touch express up / down for all windows, Rear center armrest w / retractable cupholders, Rear window defroster w / auto shutoff, Smartkey system - inc: selectively remote central unlock / locking system, engine disabling security feature, outside control of windows / sunroof, Tele Aid GPS system - inc: 24 hr cellular link to provide emergency aid, information & roadside assistance, automatic collision / alarm notification, stolen vehicle tracking, remote keyless unlocking services, 17 x 7.5 7 - spoke aluminum - alloy wheels,4 - wheel electronic traction system (4 - ETS), 5 - speed automatic transmission w / touch shift & 2nd gear start, 5.0 L SOHC SMPI 24 - valve aluminum - alloy V8 engine, Airmatic air suspension w / adaptive damping system, All wheel drive,Anti - lock braking system (ABS), Brake assist system (applies full braking pwr automatically when needed), Cross-drilled vented front / rear disc brakes w / front Brembo 4 - piston calipers, rear 2 - piston calipers, Electronic brake force distribution, Independent 4 - link front suspension w / anti-dive geometry, Independent 5 - link rear suspension w / anti-dive geometry, P225 / 55HR17 all - season performance SBR tires,Speed - sensitive pwr rack & pinion steering,3 - point seat belts for all seating positions,Anti - lock braking system (ABS), Driver programmable daytime running headlamps, Driver / front passenger front air bag, Head curtain air bag for all outboard seating positions, LATCH universal tethers / anchors for rear outboard seating positions,PRE - SAFE feature (Helps prepare occupants for a possible collision by tightening front seat belts, adjusts all pwr seats & if a possible rollover occurs, will close sunroof), Side - impact body protection air bag for all outboard seating posmemory side mirrors w / auto - dimming left - side mirror, park assist right - side mirror, Pwr tilt / sliding tinted glass sunroof w / one - touch express open / close & memory,Rain - sensing wipers w / heated washer system, heated wiper parking position, Single red rear fog lamp, (4) illuminated vanity mirrors,14 - way pwr heated adjustable memory front bucket seats w / pneumatically adjustable lumbar support, AM / FM / weatherband stereo w / CD, CD changer controls,Anti - theft alarm system w / tow - away protection, remote panic feature, auto notification via Tele Aid,Auto - dimming memory rearview mirror, Bose sound system - inc: (10) speakers, Bose Audio Pilot digital processing, Carpeted floor mats, Cruise control, Dual zone auto climate control - inc: vents in rear of console, individual left / right temp controls, rest mode, charcoal filter, humidity sensor, Front center armrest w / illuminated climate - controlled storage, retractable cupholders, Front seatback magazine pockets,Gauges - inc: electro - luminescent analog speedometer, tachometer, fuel & coolant, GPS / CD - ROM based navigation system, Hand polished burl walnut wood trim - inc: dash, console, doors, shift gate, HomeLink compatible 3 - button garage door control, Leather trimmed shift knob,Lighting - inc: front Xenon reading lamps, rear reading lamps, courtesy lamps w / programmable fade - out time, Multifunction display in speedometer face - inc: odometer, trip meter / computer, flexible service system, oil level, digital speed readout, radio / CD / phone status, Multifunction steering wheel - inc: audio, phone, climate & multifunction display controls, Nappa leather seating surfaces, Premium leather upholstery - inc: head restraints, center armrests, door trim inserts, Pwr rear window sunshade w / one - touch express up / down, Pwr tilt / telescopic leather trimmed steering wheel w / easy exit & memory features, Pwr windows w / one - touch express up / down for all windows, Rear center armrest w / retractable cupholders, Rear window defroster w / auto shutoff, Smartkey system - inc: selectively remote central unlock / locking system, engine disabling security feature, outside control of windows / sunroof, Tele Aid GPS system - inc: 24 hr cellular link to provide emergency aid, information & roadside assistance, automatic collision / alarm notification, stolen vehicle tracking, remote keyless unlocking services, 17 x 7.5 7 - spoke aluminum - alloy wheels,4 - wheel electronic traction system (4 - ETS), 5 - speed automatic transmission w / touch shift & 2nd gear start, 5.0 L SOHC SMPI 24 - valve aluminum - alloy V8 engine, Airmatic air suspension w / adaptive damping system, All wheel drive,Anti - lock braking system (ABS), Brake assist system (applies full braking pwr automatically when needed), Cross-drilled vented front / rear disc brakes w / front Brembo 4 - piston calipers, rear 2 - piston calipers, Electronic brake force distribution, Independent 4 - link front suspension w / anti-dive geometry, Independent 5 - link rear suspension w / anti-dive geometry, P225 / 55HR17 all - season performance SBR tires,Speed - sensitive pwr rack & pinion steering,3 - point seat belts for all seating positions,Anti - lock braking system (ABS), Driver programmable daytime running headlamps, Driver / front passenger front air bag, Head curtain air bag for all outboard seating positions, LATCH universal tethers / anchors for rear outboard seating positions,PRE - SAFE feature (Helps prepare occupants for a possible collision by tightening front seat belts, adjusts all pwr seats & if a possible rollover occurs, will close sunroof), Side - impact body protection air bag for all outboard seating posmemory,Rain - sensing wipers w / heated washer system, heated wiper parking position, Single red rear fog lamp, (4) illuminated vanity mirrors,14 - way pwr heated adjustable memory front bucket seats w / pneumatically adjustable lumbar support, AM / FM / weatherband stereo w / CD, CD changer controls,Anti - theft alarm system w / tow - away protection, remote panic feature, auto notification via Tele Aid,Auto - dimming memory rearview mirror, Bose sound system - inc: (10) speakers, Bose Audio Pilot digital processing, Carpeted floor mats, Cruise control, Dual zone auto climate control - inc: vents in rear of console, individual left / right temp controls, rest mode, charcoal filter, humidity sensor, Front center armrest w / illuminated climate - controlled storage, retractable cupholders, Front seatback magazine pockets,Gauges - inc: electro - luminescent analog speedometer, tachometer, fuel & coolant, GPS / CD - ROM based navigation system, Hand polished burl walnut wood trim - inc: dash, console, doors, shift gate, HomeLink compatible 3 - button garage door control, Leather trimmed shift knob,Lighting - inc: front Xenon reading lamps, rear reading lamps, courtesy lamps w / programmable fade - out time, Multifunction display in speedometer face - inc: odometer, trip meter / computer, flexible service system, oil level, digital speed readout, radio / CD / phone status, Multifunction steering wheel - inc: audio, phone, climate & multifunction display controls, Nappa leather seating surfaces, Premium leather upholstery - inc: head restraints, center armrests, door trim inserts, Pwr rear window sunshade w / one - touch express up / down, Pwr tilt / telescopic leather trimmed steering wheel w / easy exit & memory features, Pwr windows w / one - touch express up / down for all windows, Rear center armrest w / retractable cupholders, Rear window defroster w / auto shutoff, Smartkey system - inc: selectively remote central unlock / locking system, engine disabling security feature, outside control of windows / sunroof, Tele Aid GPS system - inc: 24 hr cellular link to provide emergency aid, information & roadside assistance, automatic collision / alarm notification, stolen vehicle tracking, remote keyless unlocking services, 17 x 7.5 7 - spoke aluminum - alloy wheels,4 - wheel electronic traction system (4 - ETS), 5 - speed automatic transmission w / touch shift & 2nd gear start, 5.0 L SOHC SMPI 24 - valve aluminum - alloy V8 engine, Airmatic air suspension w / adaptive damping system, All wheel drive,Anti - lock braking system (ABS), Brake assist system (applies full braking pwr automatically when needed), Cross-drilled vented front / rear disc brakes w / front Brembo 4 - piston calipers, rear 2 - piston calipers, Electronic brake force distribution, Independent 4 - link front suspension w / anti-dive geometry, Independent 5 - link rear suspension w / anti-dive geometry, P225 / 55HR17 all - season performance SBR tires,Speed - sensitive pwr rack & pinion steering,3 - point seat belts for all seating positions,Anti - lock braking system (ABS), Driver programmable daytime running headlamps, Driver / front passenger front air bag, Head curtain air bag for all outboard seating positions, LATCH universal tethers / anchors for rear outboard seating positions,PRE - SAFE feature (Helps prepare occupants for a possible collision by tightening front seat belts, adjusts all pwr seats & if a possible rollover occurs, will close sunroof), Side - impact body protection air bag for all outboard seating posmemory front bucket seats w / pneumatically adjustable lumbar support, AM / FM / weatherband stereo w / CD, CD changer controls,Anti - theft alarm system w / tow - away protection, remote panic feature, auto notification via Tele Aid,Auto - dimming memory rearview mirror, Bose sound system - inc: (10) speakers, Bose Audio Pilot digital processing, Carpeted floor mats, Cruise control, Dual zone auto climate control - inc: vents in rear of console, individual left / right temp controls, rest mode, charcoal filter, humidity sensor, Front center armrest w / illuminated climate - controlled storage, retractable cupholders, Front seatback magazine pockets,Gauges - inc: electro - luminescent analog speedometer, tachometer, fuel & coolant, GPS / CD - ROM based navigation system, Hand polished burl walnut wood trim - inc: dash, console, doors, shift gate, HomeLink compatible 3 - button garage door control, Leather trimmed shift knob,Lighting - inc: front Xenon reading lamps, rear reading lamps, courtesy lamps w / programmable fade - out time, Multifunction display in speedometer face - inc: odometer, trip meter / computer, flexible service system, oil level, digital speed readout, radio / CD / phone status, Multifunction steering wheel - inc: audio, phone, climate & multifunction display controls, Nappa leather seating surfaces, Premium leather upholstery - inc: head restraints, center armrests, door trim inserts, Pwr rear window sunshade w / one - touch express up / down, Pwr tilt / telescopic leather trimmed steering wheel w / easy exit & memory features, Pwr windows w / one - touch express up / down for all windows, Rear center armrest w / retractable cupholders, Rear window defroster w / auto shutoff, Smartkey system - inc: selectively remote central unlock / locking system, engine disabling security feature, outside control of windows / sunroof, Tele Aid GPS system - inc: 24 hr cellular link to provide emergency aid, information & roadside assistance, automatic collision / alarm notification, stolen vehicle tracking, remote keyless unlocking services, 17 x 7.5 7 - spoke aluminum - alloy wheels,4 - wheel electronic traction system (4 - ETS), 5 - speed automatic transmission w / touch shift & 2nd gear start, 5.0 L SOHC SMPI 24 - valve aluminum - alloy V8 engine, Airmatic air suspension w / adaptive damping system, All wheel drive,Anti - lock braking system (ABS), Brake assist system (applies full braking pwr automatically when needed), Cross-drilled vented front / rear disc brakes w / front Brembo 4 - piston calipers, rear 2 - piston calipers, Electronic brake force distribution, Independent 4 - link front suspension w / anti-dive geometry, Independent 5 - link rear suspension w / anti-dive geometry, P225 / 55HR17 all - season performance SBR tires,Speed - sensitive pwr rack & pinion steering,3 - point seat belts for all seating positions,Anti - lock braking system (ABS), Driver programmable daytime running headlamps, Driver / front passenger front air bag, Head curtain air bag for all outboard seating positions, LATCH universal tethers / anchors for rear outboard seating positions,PRE - SAFE feature (Helps prepare occupants for a possible collision by tightening front seat belts, adjusts all pwr seats & if a possible rollover occurs, will close sunroof), Side - impact body protection air bag for all outboard seating posmemory rearview mirror, Bose sound system - inc: (10) speakers, Bose Audio Pilot digital processing, Carpeted floor mats, Cruise control, Dual zone auto climate control - inc: vents in rear of console, individual left / right temp controls, rest mode, charcoal filter, humidity sensor, Front center armrest w / illuminated climate - controlled storage, retractable cupholders, Front seatback magazine pockets,Gauges - inc: electro - luminescent analog speedometer, tachometer, fuel & coolant, GPS / CD - ROM based navigation system, Hand polished burl walnut wood trim - inc: dash, console, doors, shift gate, HomeLink compatible 3 - button garage door control, Leather trimmed shift knob,Lighting - inc: front Xenon reading lamps, rear reading lamps, courtesy lamps w / programmable fade - out time, Multifunction display in speedometer face - inc: odometer, trip meter / computer, flexible service system, oil level, digital speed readout, radio / CD / phone status, Multifunction steering wheel - inc: audio, phone, climate & multifunction display controls, Nappa leather seating surfaces, Premium leather upholstery - inc: head restraints, center armrests, door trim inserts, Pwr rear window sunshade w / one - touch express up / down, Pwr tilt / telescopic leather trimmed steering wheel w / easy exit & memory features, Pwr windows w / one - touch express up / down for all windows, Rear center armrest w / retractable cupholders, Rear window defroster w / auto shutoff, Smartkey system - inc: selectively remote central unlock / locking system, engine disabling security feature, outside control of windows / sunroof, Tele Aid GPS system - inc: 24 hr cellular link to provide emergency aid, information & roadside assistance, automatic collision / alarm notification, stolen vehicle tracking, remote keyless unlocking services, 17 x 7.5 7 - spoke aluminum - alloy wheels,4 - wheel electronic traction system (4 - ETS), 5 - speed automatic transmission w / touch shift & 2nd gear start, 5.0 L SOHC SMPI 24 - valve aluminum - alloy V8 engine, Airmatic air suspension w / adaptive damping system, All wheel drive,Anti - lock braking system (ABS), Brake assist system (applies full braking pwr automatically when needed), Cross-drilled vented front / rear disc brakes w / front Brembo 4 - piston calipers, rear 2 - piston calipers, Electronic brake force distribution, Independent 4 - link front suspension w / anti-dive geometry, Independent 5 - link rear suspension w / anti-dive geometry, P225 / 55HR17 all - season performance SBR tires,Speed - sensitive pwr rack & pinion steering,3 - point seat belts for all seating positions,Anti - lock braking system (ABS), Driver programmable daytime running headlamps, Driver / front passenger front air bag, Head curtain air bag for all outboard seating positions, LATCH universal tethers / anchors for rear outboard seating positions,PRE - SAFE feature (Helps prepare occupants for a possible collision by tightening front seat belts, adjusts all pwr seats & if a possible rollover occurs, will close sunroof), Side - impact body protection air bag for all outboard seating posmemory features, Pwr windows w / one - touch express up / down for all windows, Rear center armrest w / retractable cupholders, Rear window defroster w / auto shutoff, Smartkey system - inc: selectively remote central unlock / locking system, engine disabling security feature, outside control of windows / sunroof, Tele Aid GPS system - inc: 24 hr cellular link to provide emergency aid, information & roadside assistance, automatic collision / alarm notification, stolen vehicle tracking, remote keyless unlocking services, 17 x 7.5 7 - spoke aluminum - alloy wheels,4 - wheel electronic traction system (4 - ETS), 5 - speed automatic transmission w / touch shift & 2nd gear start, 5.0 L SOHC SMPI 24 - valve aluminum - alloy V8 engine, Airmatic air suspension w / adaptive damping system, All wheel drive,Anti - lock braking system (ABS), Brake assist system (applies full braking pwr automatically when needed), Cross-drilled vented front / rear disc brakes w / front Brembo 4 - piston calipers, rear 2 - piston calipers, Electronic brake force distribution, Independent 4 - link front suspension w / anti-dive geometry, Independent 5 - link rear suspension w / anti-dive geometry, P225 / 55HR17 all - season performance SBR tires,Speed - sensitive pwr rack & pinion steering,3 - point seat belts for all seating positions,Anti - lock braking system (ABS), Driver programmable daytime running headlamps, Driver / front passenger front air bag, Head curtain air bag for all outboard seating positions, LATCH universal tethers / anchors for rear outboard seating positions,PRE - SAFE feature (Helps prepare occupants for a possible collision by tightening front seat belts, adjusts all pwr seats & if a possible rollover occurs, will close sunroof), Side - impact body protection air bag for all outboard seating positions

ABS,4 - Wheel Disc Brakes,7 - Speed A / T, A / C, A / T, Adjustable Steering Wheel, Security System, All Wheel Drive, Aluminum Wheels, AM / FM Stereo, Transmission w / Dual Shift Mode, Automatic Headlights, Auxiliary Audio Input, Brake Assist, Bucket Seats, CD Player, Child Safety Locks, Climate Control, Temporary Spare Tire, Cruise Control, Daytime Running Lights, Driver Air Bag, Driver Illuminated Vanity Mirror, Driver Adjustable Lumbar, Driver Vanity Mirror,Multi - Zone A / C, Auto - Dimming Rearview Mirror, Stability Control, Fog Lamps, Floor Mats, Gasoline Fuel, Heated Mirrors, Integrated Turn Signal Mirrors, Intermittent Wipers, Keyless Entry, Leather Steering Wheel, Mirror Memory, MP3 Player, Telematics, Passenger Air Bag, Passenger Air Bag Sensor, Passenger Illuminated Visor Mirror, Passenger Adjustable Lumbar, Passenger Vanity Mirror, Power Door Locks, Power Mirror (s), Power Driver Seat, Power Passenger Seat, Power Steering, Power Windows, Rain Sensing Wipers, Rear Bench Seat, Rear Defrost, Rear Head Air Bag, Remote Trunk Release, Seat Memory, Front Side Air Bag, Front Head Air Bag, Steering Wheel Audio Controls, Sun / Moon Roof, Tire Pressure Monitor, Tires - Front Performance, Tires - Rear Performance, Traction Control, Trip Computer, Universal Garage Door Opener, V6 Cylinder Engine, Variable Speed Intermittent Wipers, Engine Immobilizer, Bluetooth Connection, Woodgrain Interior Trim, Black Side Windows Trim and Black Front Windshield Trim,Body - Colored Bodyside Moldings and Chrome Bodyside Insert,Body - Colored Front Bumper w / Body - Colored Rub Strip / Fascia Accent and Chrome Bumper Insert,Body - Colored Power Heated Side Mirrors w / Driver Auto Dimming, Manual Folding and Turn Signal Indicator,Body - Colored Rear Bumper w / Body - Colored Rub Strip / Fascia Accent and Chrome Bumper Insert, Chrome Door Handles, Chrome Grille, Clearcoat Paint, Compact Spare Tire Mounted Inside Under Cargo, Express Open / Close Sliding And Tilting Glass 1st Row Sunroof w / Sunshade, Fixed Rear Window w / Defroster, Front And Rear Fog Lamps, Fully Automatic Projector Beam Led Low Beam Daytime Running Headlamps w / Delay - Off, Galvanized Steel / Aluminum Panels, LED Brakelights, Light Tinted Glass, Perimeter / Approach Lights, Radiator Grille w / Central Star, Rain Detecting Variable Intermittent Wipers w / Heated Jets And Reservoir, Sport Bodystyling, Steel Spare Wheel, Tires: P245 / 40R18 All Season, Tires: P245 / 45R17 AS, Trunk Rear Cargo Access, Wheels: 17 5 - Spoke Wheels, Wheels: 18 5 - Double Spoke Alloy, 2 Seatback Storage Pockets, 3 12V DC Power Outlets,8 - Way Driver Seat,8 - Way Passenger Seat, Air Filtration, Analog Display, Ashtray, Bench Front Facing Leatherette Rear Seat, Cargo Space Lights, Carpet Floor Trim and Carpet Trunk Lid / Rear Cargo Door Trim, Cruise Control,Day - Night Auto - Dimming Rearview Mirror, Delayed Accessory Power, Driver And Passenger Visor Vanity Mirrors w / Driver And Passenger Illumination and Driver And Passenger Auxiliary Mirror, Driver Foot Rest, Dual Zone Front Automatic Air Conditioning, Engine Immobilizer,Fade - To - Off Interior Lighting, FOB Controls - inc: Trunk / Hatch / Tailgate, Windows and Sunroof / Convertible Roof, Front And Rear Map Lights, Front Center Armrest and Rear Center Armrest w / Storage, Front Cigar Lighter (s), Front Cupholder, Full Carpet Floor Covering - inc: Carpet Front And Rear Floor Mats, Full Cloth Headliner, Full Floor Console w / Covered Storage, Mini Overhead Console and 3 12V DC Power Outlets, Gauges - inc: Speedometer, Odometer, Engine Coolant Temp, Tachometer, Trip Odometer and Trip Computer, Homelink Garage Door Transmitter, HVAC - inc: Underseat Ducts, Residual Heat Recirculation and Console Ducts, Illuminated Locking Glove Box, Instrument Panel Covered Bin and Driver / Passenger And Rear Door Bins, Interior Trim - inc: Genuine Wood / Metal - Look Instrument Panel Insert, Genuine Wood / Metal - Look Door Panel Insert, Genuine Wood / Metal - Look Console Insert and Chrome Interior Accents, Leather Steering Wheel w / Auto Tilt - Away, Leather / Metal - Look Gear Shift Knob, Leatherette Door Trim Insert, Leatherette Front Seats w / Leatherette Back Material, Outside Temp Gauge, Perimeter Alarm, Power 1st Row Windows w / Front And Rear 1 - Touch Up / Down, Power Adjustable Front Seats - inc: lumbar adjustment and 3 - position memory, Power Door Locks w / Autolock Feature, Power Fuel Flap Locking Type, Power Rear Windows, Power Tilt / Telescoping Steering Column, Power Type Adjustable Front Head Restraints and Power Adjustable Rear Head Restraints, Rear Cupholder, Redundant Digital Speedometer, Remote Keyless Entry w / Integrated Key Transmitter, 4 Door Curb / Courtesy, Illuminated Entry, Illuminated Ignition Switch and Panic Button, Remote Releases - Inc: Power Trunk / Hatch and Keyfob Fuel, Selective Service Internet Access, Steering Wheel and Head Restraints, Systems Monitor, Tracker System, Trip Computer, Valet Function,100 - Amp / Hr 850CCA Maintenance - Free Battery, 180 Amp Alternator, 21.Memory, MP3 Player, Telematics, Passenger Air Bag, Passenger Air Bag Sensor, Passenger Illuminated Visor Mirror, Passenger Adjustable Lumbar, Passenger Vanity Mirror, Power Door Locks, Power Mirror (s), Power Driver Seat, Power Passenger Seat, Power Steering, Power Windows, Rain Sensing Wipers, Rear Bench Seat, Rear Defrost, Rear Head Air Bag, Remote Trunk Release, Seat Memory, Front Side Air Bag, Front Head Air Bag, Steering Wheel Audio Controls, Sun / Moon Roof, Tire Pressure Monitor, Tires - Front Performance, Tires - Rear Performance, Traction Control, Trip Computer, Universal Garage Door Opener, V6 Cylinder Engine, Variable Speed Intermittent Wipers, Engine Immobilizer, Bluetooth Connection, Woodgrain Interior Trim, Black Side Windows Trim and Black Front Windshield Trim,Body - Colored Bodyside Moldings and Chrome Bodyside Insert,Body - Colored Front Bumper w / Body - Colored Rub Strip / Fascia Accent and Chrome Bumper Insert,Body - Colored Power Heated Side Mirrors w / Driver Auto Dimming, Manual Folding and Turn Signal Indicator,Body - Colored Rear Bumper w / Body - Colored Rub Strip / Fascia Accent and Chrome Bumper Insert, Chrome Door Handles, Chrome Grille, Clearcoat Paint, Compact Spare Tire Mounted Inside Under Cargo, Express Open / Close Sliding And Tilting Glass 1st Row Sunroof w / Sunshade, Fixed Rear Window w / Defroster, Front And Rear Fog Lamps, Fully Automatic Projector Beam Led Low Beam Daytime Running Headlamps w / Delay - Off, Galvanized Steel / Aluminum Panels, LED Brakelights, Light Tinted Glass, Perimeter / Approach Lights, Radiator Grille w / Central Star, Rain Detecting Variable Intermittent Wipers w / Heated Jets And Reservoir, Sport Bodystyling, Steel Spare Wheel, Tires: P245 / 40R18 All Season, Tires: P245 / 45R17 AS, Trunk Rear Cargo Access, Wheels: 17 5 - Spoke Wheels, Wheels: 18 5 - Double Spoke Alloy, 2 Seatback Storage Pockets, 3 12V DC Power Outlets,8 - Way Driver Seat,8 - Way Passenger Seat, Air Filtration, Analog Display, Ashtray, Bench Front Facing Leatherette Rear Seat, Cargo Space Lights, Carpet Floor Trim and Carpet Trunk Lid / Rear Cargo Door Trim, Cruise Control,Day - Night Auto - Dimming Rearview Mirror, Delayed Accessory Power, Driver And Passenger Visor Vanity Mirrors w / Driver And Passenger Illumination and Driver And Passenger Auxiliary Mirror, Driver Foot Rest, Dual Zone Front Automatic Air Conditioning, Engine Immobilizer,Fade - To - Off Interior Lighting, FOB Controls - inc: Trunk / Hatch / Tailgate, Windows and Sunroof / Convertible Roof, Front And Rear Map Lights, Front Center Armrest and Rear Center Armrest w / Storage, Front Cigar Lighter (s), Front Cupholder, Full Carpet Floor Covering - inc: Carpet Front And Rear Floor Mats, Full Cloth Headliner, Full Floor Console w / Covered Storage, Mini Overhead Console and 3 12V DC Power Outlets, Gauges - inc: Speedometer, Odometer, Engine Coolant Temp, Tachometer, Trip Odometer and Trip Computer, Homelink Garage Door Transmitter, HVAC - inc: Underseat Ducts, Residual Heat Recirculation and Console Ducts, Illuminated Locking Glove Box, Instrument Panel Covered Bin and Driver / Passenger And Rear Door Bins, Interior Trim - inc: Genuine Wood / Metal - Look Instrument Panel Insert, Genuine Wood / Metal - Look Door Panel Insert, Genuine Wood / Metal - Look Console Insert and Chrome Interior Accents, Leather Steering Wheel w / Auto Tilt - Away, Leather / Metal - Look Gear Shift Knob, Leatherette Door Trim Insert, Leatherette Front Seats w / Leatherette Back Material, Outside Temp Gauge, Perimeter Alarm, Power 1st Row Windows w / Front And Rear 1 - Touch Up / Down, Power Adjustable Front Seats - inc: lumbar adjustment and 3 - position memory, Power Door Locks w / Autolock Feature, Power Fuel Flap Locking Type, Power Rear Windows, Power Tilt / Telescoping Steering Column, Power Type Adjustable Front Head Restraints and Power Adjustable Rear Head Restraints, Rear Cupholder, Redundant Digital Speedometer, Remote Keyless Entry w / Integrated Key Transmitter, 4 Door Curb / Courtesy, Illuminated Entry, Illuminated Ignition Switch and Panic Button, Remote Releases - Inc: Power Trunk / Hatch and Keyfob Fuel, Selective Service Internet Access, Steering Wheel and Head Restraints, Systems Monitor, Tracker System, Trip Computer, Valet Function,100 - Amp / Hr 850CCA Maintenance - Free Battery, 180 Amp Alternator, 21.Memory, Front Side Air Bag, Front Head Air Bag, Steering Wheel Audio Controls, Sun / Moon Roof, Tire Pressure Monitor, Tires - Front Performance, Tires - Rear Performance, Traction Control, Trip Computer, Universal Garage Door Opener, V6 Cylinder Engine, Variable Speed Intermittent Wipers, Engine Immobilizer, Bluetooth Connection, Woodgrain Interior Trim, Black Side Windows Trim and Black Front Windshield Trim,Body - Colored Bodyside Moldings and Chrome Bodyside Insert,Body - Colored Front Bumper w / Body - Colored Rub Strip / Fascia Accent and Chrome Bumper Insert,Body - Colored Power Heated Side Mirrors w / Driver Auto Dimming, Manual Folding and Turn Signal Indicator,Body - Colored Rear Bumper w / Body - Colored Rub Strip / Fascia Accent and Chrome Bumper Insert, Chrome Door Handles, Chrome Grille, Clearcoat Paint, Compact Spare Tire Mounted Inside Under Cargo, Express Open / Close Sliding And Tilting Glass 1st Row Sunroof w / Sunshade, Fixed Rear Window w / Defroster, Front And Rear Fog Lamps, Fully Automatic Projector Beam Led Low Beam Daytime Running Headlamps w / Delay - Off, Galvanized Steel / Aluminum Panels, LED Brakelights, Light Tinted Glass, Perimeter / Approach Lights, Radiator Grille w / Central Star, Rain Detecting Variable Intermittent Wipers w / Heated Jets And Reservoir, Sport Bodystyling, Steel Spare Wheel, Tires: P245 / 40R18 All Season, Tires: P245 / 45R17 AS, Trunk Rear Cargo Access, Wheels: 17 5 - Spoke Wheels, Wheels: 18 5 - Double Spoke Alloy, 2 Seatback Storage Pockets, 3 12V DC Power Outlets,8 - Way Driver Seat,8 - Way Passenger Seat, Air Filtration, Analog Display, Ashtray, Bench Front Facing Leatherette Rear Seat, Cargo Space Lights, Carpet Floor Trim and Carpet Trunk Lid / Rear Cargo Door Trim, Cruise Control,Day - Night Auto - Dimming Rearview Mirror, Delayed Accessory Power, Driver And Passenger Visor Vanity Mirrors w / Driver And Passenger Illumination and Driver And Passenger Auxiliary Mirror, Driver Foot Rest, Dual Zone Front Automatic Air Conditioning, Engine Immobilizer,Fade - To - Off Interior Lighting, FOB Controls - inc: Trunk / Hatch / Tailgate, Windows and Sunroof / Convertible Roof, Front And Rear Map Lights, Front Center Armrest and Rear Center Armrest w / Storage, Front Cigar Lighter (s), Front Cupholder, Full Carpet Floor Covering - inc: Carpet Front And Rear Floor Mats, Full Cloth Headliner, Full Floor Console w / Covered Storage, Mini Overhead Console and 3 12V DC Power Outlets, Gauges - inc: Speedometer, Odometer, Engine Coolant Temp, Tachometer, Trip Odometer and Trip Computer, Homelink Garage Door Transmitter, HVAC - inc: Underseat Ducts, Residual Heat Recirculation and Console Ducts, Illuminated Locking Glove Box, Instrument Panel Covered Bin and Driver / Passenger And Rear Door Bins, Interior Trim - inc: Genuine Wood / Metal - Look Instrument Panel Insert, Genuine Wood / Metal - Look Door Panel Insert, Genuine Wood / Metal - Look Console Insert and Chrome Interior Accents, Leather Steering Wheel w / Auto Tilt - Away, Leather / Metal - Look Gear Shift Knob, Leatherette Door Trim Insert, Leatherette Front Seats w / Leatherette Back Material, Outside Temp Gauge, Perimeter Alarm, Power 1st Row Windows w / Front And Rear 1 - Touch Up / Down, Power Adjustable Front Seats - inc: lumbar adjustment and 3 - position memory, Power Door Locks w / Autolock Feature, Power Fuel Flap Locking Type, Power Rear Windows, Power Tilt / Telescoping Steering Column, Power Type Adjustable Front Head Restraints and Power Adjustable Rear Head Restraints, Rear Cupholder, Redundant Digital Speedometer, Remote Keyless Entry w / Integrated Key Transmitter, 4 Door Curb / Courtesy, Illuminated Entry, Illuminated Ignition Switch and Panic Button, Remote Releases - Inc: Power Trunk / Hatch and Keyfob Fuel, Selective Service Internet Access, Steering Wheel and Head Restraints, Systems Monitor, Tracker System, Trip Computer, Valet Function,100 - Amp / Hr 850CCA Maintenance - Free Battery, 180 Amp Alternator, 21.memory, Power Door Locks w / Autolock Feature, Power Fuel Flap Locking Type, Power Rear Windows, Power Tilt / Telescoping Steering Column, Power Type Adjustable Front Head Restraints and Power Adjustable Rear Head Restraints, Rear Cupholder, Redundant Digital Speedometer, Remote Keyless Entry w / Integrated Key Transmitter, 4 Door Curb / Courtesy, Illuminated Entry, Illuminated Ignition Switch and Panic Button, Remote Releases - Inc: Power Trunk / Hatch and Keyfob Fuel, Selective Service Internet Access, Steering Wheel and Head Restraints, Systems Monitor, Tracker System, Trip Computer, Valet Function,100 - Amp / Hr 850CCA Maintenance - Free Battery, 180 Amp Alternator, 21.1 Gal.

FULL SERVICE HISTORY ** FINANCE AVAILABLE ** GRAPHITE GREY METTALIC WITH LIGHT SAND LEATHER HEATED SEATS, 12 MTHS MOT NO ADVISORYS, PARKING SENSORS, EXCELLENT DRIVE, Next MOT due 24/05/2019, Last serviced on 27/09/2017 at 99,398 miles, Full service history, 12V Socket (Front and Rear Tunnel Console / Cargo Area), 17in Cassini Alloy Wheels (Silver Bright)- 225/50 R17 W Tyres with Locking Wheel Nuts, 4 x 40W Amplifier, 8 Speakers, ABS (Anti-Lock Brake System) and FBS (Fading Brake Support) with HBA (Hydraulic Brake Assist), OHB (Optimised Hydraulic Brakes), Anti-Theft Alarm and Level Sensor, Autodimming Rear View Mirror with Compass, Autofolding, Power Adjustable and Heated Door Mirrors with Ground Lights, Body Coloured Bumpers, Centre Console, Centre Rear Seat Belt, Colour Co - Ordinated Lower Door and Bumper Mouldings, Cross Brushed Aluminium Trim, Cruise Control, DSTC (Dynamic Stability Control), Day Running Lights, Deadlocking System, Drivers and Passengers Lumbar Support, Dual Chamber SIPS Airbags, IC (Inflatable Curtains), Dual Stage Drivers Airbag, Dual Stage Passengers Airbag, EBD (Electronic Brake Distribution), ECC (Electronic Climate Control) with AQS (Air Quality System) and Pollen Filter, Front Fog Lights, Front and Rear Power Windows, Front and Rear Reading Lights, Head Light Sensor, Head Restraints Front / Rear, Heated Rear Screen, Height and Reach Adjustable Steering Column, High Level LED Brake Light, High Performance Audio System - 1x Radio / CD, Aux Input (MP3 / WMA Compatible), IDIS (Intelligent Driver Information System) with Information Centre, ISOFIX Attachment - Rear Seats, Immobiliser, Key Integrated Remote Control Central Locking Including Fuel Flap, Leather Gear Knob, Leather Steering Wheel, Power Assisted Steering, Power Drivers Seat with Seat Memory, Power Height Adjustable Drivers Seat and Manual Adjustable Passengers Seat, Power Parking Brake, Rain Sensor - Automatic Windscreen Wiper Activation, Rear Centre Armrest, Rear Cupholders (Armrest), Roof Rails, Seat Belt Pre-Tensioners (Front and Rear), Steering Wheel Remote Audio Controls, Sun Visor with Illuminated Driver and Passenger Vanity Mirrors, Tinted Windows, Traction Control, Tyre Sealant Kit, Upholstery - Sundby Textile / T - Tec Upholstery, Versatile Split - Folding Rear Seat (40/20/40), WHIPS (Whiplash Protection System).