The protein causes familial human
cerebral amyloid angiopathy (CAA), and the study, which appears in Nature Communications, is the first to examine forms of the protein in three different species.
Small - vessel disease could provoke amyloid pathology while AD -
associated cerebral amyloid pathology may lead to auxiliary vascular damage,» researchers conclude.
In addition, neurofibrillary tangles pathology was observed in apes that exhibited plaques and moderate or
severe cerebral amyloid angiopathy and in one individual with virtually no amyloid beta pathology.
In particular, during the predoctoral and postdoctoral periods, I studied the molecular mechanisms involved in the neurovascular disorder known
as cerebral amyloid angiopathy (CAA).
APOE and BCHE as modulators
of cerebral amyloid deposition: a florbetapir PET genome - wide association study.
Abstract: Background: Specific APP mutations
cause cerebral amyloid angiopathy (CAA) with or without Alzheimer's disease (AD).
While approximately 80 percent of Alzheimer's disease patients also have
cerebral amyloid angiopathy, or amyloid beta deposits in the brain's blood vessels that increase the risk for stroke and dementia, the predominant amyloid beta pathology is plaques.
Spatial distribution of white - matter hyperintensities in Alzheimer disease,
cerebral amyloid angiopathy, and healthy aging.
Abstract:
Cerebral amyloid angiopathy (CAA) is a contributor to cognitive impairment in the elderly.
Keywords:
Cerebral amyloid angiopathy, neuroimaging markers, neuropsychological assessment, visuospatial functioning
Cerebral amyloid angiopathy (CAA) is a contributor to cognitive impairment in the elderly.
Dr. Mar Hernández - Guillamon has dedicated her career to the study of Aβ - associated pathologies, including AD and
cerebral amyloid angiopathy.
In 2012, she was awarded the Miguel Servet grant from the Spanish government to start her own research group, which is
the Cerebral Amyloid Angiopathy laboratory at the Vall d'Hebron Research Institute, Barcelona.
Based on prior studies, it was assumed that at this age
no cerebral amyloid plaques were likely to be present.
Affected family members presented between 61 and 74 years, with variable presence of microbleeds /
cerebral amyloid angiopathy and electroencephalographic abnormalities.
Keywords: Alzheimer's disease, amyloid - β, APP, calcification,
cerebral amyloid angiopathy, mutation
Phrases with «cerebral amyloid»