October 5, 2015 / Novato, California Following an exhaustive, ten - year effort, scientists at the Buck Institute for Research on Aging and the University of Washington have identified 238 genes that, when removed, increase the replicative lifespan of S.
cerevisiae yeast cells.
Not exact matches
The role of DNA topology in holding sister chromatids together before anaphase was investigated by analyzing the structure of a small circular minichromosome in
cell cycle (cdc) mutants of the
yeast Saccharomyces
cerevisiae.
An enzyme identified in Saccharomyces
cerevisiae, commonly known as brewer's or baker's
yeast, has passed in vitro trials, demonstrating its capacity to kill acute lymphoblastic leukemia (ALL)
cells.
She still does not know why he considered her at the time — «Maybe it was just my enthusiasm,» she wonders — but he nonetheless became her mentor as she studied the transcriptional activation of the
cell - cycle regulated HO gene in the
yeast Saccharomyces
cerevisiae.
While researching the life cycle of baker's
yeast, Saccharomyces
cerevisiae, Gottschling's team figured out a way to label
yeast so that they could spot genetic mistakes in daughter
cells.
The budding
yeast, Saccharomyces
cerevisiae, is a prime organism for studying fundamental cellular processes, with the functions of many proteins important in the
cell cycle and signaling networks found in human biology having first been discovered in
yeast.
Now, researchers reporting in the
Cell Press journal
Cell Reports on October 9th have discovered why the
yeast (formally known as S.
cerevisiae) make that smell: the scent attracts fruit flies, which repay the
yeast by dispersing their
cells in the environment.
A team led by Rong Li of the Stowers Institute for Medical Research in Kansas City, Missouri, exposed baker's
yeast cells (Saccharomyces
cerevisiae) to stressful stimuli like heat and chemicals, and looked for changes in chromosome replication.
The
yeast Saccharomyces
cerevisiae, which normally occurs as a single
cell, has the ability to form colonies featuring multicellular structures with divided responsibilities, meaning the
cells differentiate to perform different tasks.
The
yeast Saccharomyces
cerevisiae, which normally occurs as a single
cell, has the ability to form colonies as it is able to duplicate single chromosomes.
Given his training in developmental biology, Raman focused the team to seek a novel drug target on genes important to the development of model organisms — fruit flies (Drosophila) and
yeast (Saccharomyces
cerevisiae)-- rather than on oncogenes that transform a normal
cell into a cancer
cell.
The group took the first step toward their goal of a novel engineering strategy for
yeast by creating what is known as a cDNA library: a collection of over 90 % of the genes from the genome of baker's
yeast (Saccharomyces
cerevisiae), arranged within a custom segment of DNA so that each gene will be, in one version, overactive within a
yeast cell, and in a second version, reduced in activity.
Protein expression systems: E. coli,
yeast (S.
cerevisiae), baculovirus (in insect
cells — Sf9), mammalian
cells (Flp - In system HEK293
cells),
cell - free protein expression
Cell wall integrity signalling in the
yeast S.
cerevisiae.
In a new study in GENETICS, Hoffmann and coworkers show that spore wall lipid droplets, organelles used to move neutral lipids to the
cell wall in the
yeast Saccharomyces
cerevisiae, have a surprise component, too.
These methods integrate single -
cell experiments and discrete stochastic analysis to predict complex gene expression and signaling behaviors in Saccharomyces
cerevisiae — or
yeast, a scientific - lab standard since
yeast and human
cells share many genes.
Large - scale targeted - deletions have been successful in defining gene functions in the single -
celled yeast Saccharomyces
cerevisiae, but comparable analyses have yet to be performed in an animal.
To address this, we evolve genetically diverse populations of budding
yeast, S.
cerevisiae, consisting of diploid
cells with unique haplotype combinations.
Derived from broken
cell walls brewer's
yeast (Saccharomyces
cerevisiae), Beta Glucan is a powerful immune stimulator, activating the macrophage in the immune system.
Nutritional
yeast is made from the single -
celled organism, Saccharomyces
cerevisiae, which is grown on molasses, whey or wood pulp, and then harvested, washed and dried with heat to deactivate it.