In Parkinson's disease, gobs of the protein α - synuclein accumulate
in certain brain cells and may kill them.
By studying frogs, University of Utah researchers figured out
how certain brain cells compute the length of sounds and detect short ones.
Secreted
by certain brain cells, APOE is known to regulate cholesterol metabolism within the brain and can bind to A-beta peptides, suggesting that the different forms of the protein may affect whether and how toxic A-beta plaques form.
Patients
lose certain brain cells in the hypothalamus, leading to a deficiency of hypocretin, a molecule that helps regulate the sleep - wake cycle.
Neuroscientists have long noted that
if certain brain cells are destroyed by, say, a stroke, new circuits may be laid in another location to compensate, essentially rewiring the brain.
Nor is major loss
of certain brain cells repaired, such as the losses that lead to Alzheimer's disease and Parkinson's disease.
One prominent researcher, Dr. Mary Newport, discovered that coconut oil showed exceptional promise with regards to dementia and Alzheimer's prevention, as the medium - chain triglycerides found in coconut oil
fuel certain brain cells that have a difficult time utilizing carbohydrates, the brain's main energy source.
By understanding
how certain brain cells are either vulnerable or resistant to neurodegenerative diseases, the lab has also discovered specific «profiles» of vulnerable cell types, thus advancing neuroprotective strategies for Parkinson's disease, Huntington's disease, and amyotrophic lateral sclerosis (ALS).