Sentences with phrase «certain gene pathway»

Recent studies have found that ALL cases are often characterized by mutations in a certain gene pathway, called JAK3 / STAT5.

Further work is required to consider if certain gene pathways may provide a base for useful interventions.»

Not exact matches

«However, recent work has shown that at least some of the fungal partners in arbuscular mycorrhizal symbioses lack the genes for enzymes involved in the major pathway of lipid biosynthesis, and are therefore unable to produce certain essential fatty acids,» Gutjahr explains.

- catenin pathway activates certain lncRNAs to directly control gene expression in skin fibroblast cells.»

«We found that UBQLN4 gene variant interferes with a pathway involved in breaking down a certain protein called beta catenin, and the resulting accumulation of this protein leads to defects in the motor neuron structure.

Another potential use of this information is that in certain groups, there was a similarity in the type of genes and pathways that were disrupted in the tumors.

Among other things, we plan to include certain gene therapy products that permanently alter tissue and produce a sustained therapeutic benefit as part of the products that will meet the definition of being eligible to come under the pathway enabled by RMAT.

• In nutrigenomics, the basic goal is to discover how diet affects metabolic pathways in the body and how this regulation may be disturbed in diet - related disease — i.e., humans with a certain mutated gene absorb higher levels of fat from the intestine, leading to elevated cholesterol and possible atherosclerosis.

By assessing the incidence of a particular mutation or the frequency at which certain genes / pathways are altered across multiple patients (of the same tumor type), it should be possible to identify key mutations.

Causes certain genes and metabolic pathways to be shutdown which would otherwise cause blood and chemicals to flow to wounds

In concurrent studies, the team will examine the gene expression profile of subsets of patients with different clinical outcomes to provide further insight into why certain dogs have more aggressive B - CLL and to identify possible drug targetable pathways to improve the treatment for this cancer.