Sentences with phrase «certain genes in a mouse»

Using the gene - editing tool CRISPR - Cas9 to turn off certain genes in a mouse zygote as well as other new techniques to enrich the pluripotent stem cells of a rat, the group managed to grow various rat organs (a pancreas, heart, and eyes) in a mouse embryo.

Not exact matches

Many universities and pharmaceutical companies are engaged in research and development using genetically modified mice that have certain genes manipulated to reproduce human diseases.

Based on experiments with mice, some scientists had speculated that cilia nestled in a dimple at the top of the embryo called the node might push fluid down the left side of the embryo, carrying a signal that somehow triggers certain genes to activate.

The researchers deleted the HIC1 gene in certain innate lymphoid cells in the mouse intestine and found that this increased the susceptibility of the mice to infection with the bacterium Citrobacter rodentium.

In his new study, Michael Petris, associate professor of biochemistry, was able to modify mice so that they were missing the ATP7A gene in certain areas of the body, specifically the intestinal track where nutrient absorption takes placIn his new study, Michael Petris, associate professor of biochemistry, was able to modify mice so that they were missing the ATP7A gene in certain areas of the body, specifically the intestinal track where nutrient absorption takes placin certain areas of the body, specifically the intestinal track where nutrient absorption takes place.

In the LOX deficient mice, they observed changes in mechanical behavior and in signaling of groups of genes that appeared to be a susceptibility differentiator in certain sections of tissue; the way they interacted seemed to provide some protection against aneurysIn the LOX deficient mice, they observed changes in mechanical behavior and in signaling of groups of genes that appeared to be a susceptibility differentiator in certain sections of tissue; the way they interacted seemed to provide some protection against aneurysin mechanical behavior and in signaling of groups of genes that appeared to be a susceptibility differentiator in certain sections of tissue; the way they interacted seemed to provide some protection against aneurysin signaling of groups of genes that appeared to be a susceptibility differentiator in certain sections of tissue; the way they interacted seemed to provide some protection against aneurysin certain sections of tissue; the way they interacted seemed to provide some protection against aneurysm.

They also showed that certain genes and elements are similar in both species, providing a basis to use the mouse to study relevant human disease.

The team found deep conservation of certain processes that likely reflects similar underlying regulatory processes between mouse and man, but there were also significant differences in gene expression during kidney development, as well as in the timing, scale, organization, and molecular profile of key cell types and cell structures.

In the new study, researchers mutated the gene encoding neuregulin 3 in mice — but only in certain populations of neuronIn the new study, researchers mutated the gene encoding neuregulin 3 in mice — but only in certain populations of neuronin mice — but only in certain populations of neuronin certain populations of neurons.

So when Drake and his colleagues measured the RNA levels — a direct link to how much of a gene is being produced — in the genes of 334 mice, he didn't expect to find more than a few variations that might help explain why males and females have such different rates of cardiovascular disease and diabetes or why they react differently to certain drugs.

Working with mice, Reti and others have shown previously that within a few minutes of ECT, certain genes 3/4 notably including Narp 3/4 are turned on in the hippocampus, a small, seahorse - shaped part of the brain in the temporal lobe that helps regulate emotions.

Shatz revealed that in mice which were deficient in certain MHC genes, their visual neurons were more randomly arranged and had many more synapses.

While it is possible to induce atherosclerosis in some mice, it is important to realize that the presence of cholic acid can influence transcription factors controlling genes involved with regulating lipoprotein metabolism and inflammation, both of which are important in the development of atherosclerosis (16, 17), and can also promote gallstones in certain mouse strains (18, 19).