Sentences with phrase «certain types of mutations»

In a new analysis, researchers have shed light on these hereditary elements across 12 cancer types — showing a surprising inherited component to stomach cancer and providing some needed clarity on the consequences of certain types of mutations in well - known breast cancer susceptibility genes, BRCA1 and BRCA2.

Not exact matches

Although mutations can occur anywhere in the human intestine, certain types of colorectal cancer tend to develop in particular locations, suggesting that additional, nongenetic factors contribute to tumor growth and dictate where polyps appear.

New research led by Li Ding, Ph.D., of Washington University School of Medicine in St. Louis, shows that current approaches to genome analysis systematically miss detecting a certain type of complex mutation in cancer patients» tumors.

While not all people with Lynch syndrome will develop cancer, a person who has the mutation is more likely to get certain types of cancer, including an 80 percent higher risk of colorectal cancer and a 60 percent higher risk of endometrial cancer.

Neil Johnson's lab at the Fox Chase Cancer Center examined treatment resistance in breast cancer cells expressing the same BRCA1185delAG mutation and determined that the RING - deficient BRCA1 protein was also responsible for loss of sensitivity to certain types of cancer treatments.

The researchers at Sandia and the university did molecular computer simulations to predict what mutations would produce that desirable result when introduced into the enzyme - drug L - ASN2, commonly used to treat certain types of leukemia.

Many diseases, including degenerative diseases and certain types of cancers, are associated with mutations in the machinery that makes proteins.

RET is a type of receptor tyrosine kinase, and mutations that kick its activity into overdrive are linked to certain kinds of cancer.

Bethesda, Md., Wed., May 1, 2013 - A comprehensive genomic analysis of nearly 400 endometrial tumors suggests that certain molecular characteristics - such as the frequency of mutations - could complement current pathology methods and help distinguish between principal types of endometrial tumors, as well as provide insights into potential treatment strategies.

How do genetic mutations in selected genes lead to elective degeneration in certain types of neurons in HD, PD, and ALS?

While some mutations are common to many types of cancers, other genetic changes may be unique to certain tumors.

But sometimes what we inherit remains hidden, like BRCA gene mutations which can increase your risk for developing certain type of cancers.

And if it wasn't hard enough, I heard more reports of somatic mosaicism (mutations present only in certain cell or tissue types) underlying disease susceptibility, meaning that DNA from blood cells may not be informative in some patients for some diseases.

Tens of thousands of Americans with tumors from certain types of lung cancer have mutations that might be treated by...

Hereditary: Hereditary cancer is caused by abnormal, or mutated, genes that are passed down through generations within a family, causing family members who inherit the mutation to be diagnosed with certain types of cancers.

By assessing the incidence of a particular mutation or the frequency at which certain genes / pathways are altered across multiple patients (of the same tumor type), it should be possible to identify key mutations.

X-rays and gamma rays are two other types of radiation — both of which are found naturally and in man - made devices like imaging tests, scanners, and certain power plants — that can cause DNA mutations, which may lead to cancer in the future.

That's why some people may want to be tested for these inherited gene mutations, particularly if a certain type of cancer runs in the family.