«Vaccine used to treat
cervical precancers triggers immune cell response.»
To address this gap in knowledge, Mirabello and Schiffman teamed up with co-senior author Robert Burk of Albert Einstein College of Medicine to sequence the whole genomes of 5,570 HPV16 - infected cell and tissue samples from women around the world and to identify associations between HPV16 genetic variants and the risk of
cervical precancer and cancer.
Pap tests can identify
cervical precancer before it turns into cancer.
Not exact matches
Screening histories preceding
cervical cancers (n = 623) and
precancers (n = 5,369) were examined to assess the relative contribution of the Pap test and HPV test components in identifying cases.
The main goal of
cervical screening programs is to detect and treat
precancer before cancer develops.
«We understand that people get infections, we understand that people develop low - grade abnormalities, but we also understand that the amount of
precancer is very low in these populations,» says Wheeler, who has conducted extensive research on HPV infection and
cervical cancer.