Sentences with phrase «cervical spinal cord»

High cervical spinal cord injury patients differ from both other groups in their lack of peripheral feedback and their inability to show motor approach or withdrawal behavior.

Asterias Biotherapeutics, Inc. (CA, USA) has announced that they have completely enrolling and dosing a total of 10 patients with complete cervical spinal cord injury (SCI) with OPC - 1.

«We are pleased to provide this update regarding our ongoing clinical trial of AST - OPC1 for the treatment of severe cervical spinal cord injuries in patients for whom there are no viable treatment options and a high unmet medical need,» stated Michael Mulroy, President and Chief Executive Officer.

Tactile percepts were consistently elicited in the hand of a person with cervical spinal cord injury using intracortical microstimulation of the somatosensory cortex.

Human Embryonic Stem Cell - Derived Oligodendrocyte Progenitor Cell Transplants Improve Recovery After Cervical Spinal Cord Injury.

Analysis of the diffusion tensor imaging parameters of a normal cervical spinal cord in a healthy population.

The cell therapy, called OPC - 1, is being trialled in subacute cervical spinal cord injury patients who receive the treatment 14 — 30 days post-injury.

Dorsal (A) and cross section (B) schematics of the rat cervical spinal cord showing right side unilateral transection injury (red shaded area) conducted at the level of the C3 / C4 intervertebral junction.

Transverse scans had to have included the cribiform plate rostrally and the first cervical spinal cord segment caudally.

The study seeks male and female patients ages 18 to 65 who recently experienced a complete cervical spinal cord injury at the neck that resulted in tetraplegia, the partial or total paralysis of arms, legs and torso.

FREMONT, Calif., Feb. 28, 2018 (GLOBE NEWSWIRE)-- Asterias Biotherapeutics, Inc. (NYSE American: AST), a biotechnology company dedicated to developing cell - based therapeutics to treat neurological conditions associated with demyelination and cellular immunotherapies to treat cancer, today provided additional data from the company's ongoing Phase 1 / 2a SCiStar study designed to evaluate the safety and potential efficacy of AST - OPC1 in the treatment of severe cervical spinal cord injury.

The diagram on the cover shows the changes and processes affecting the body after death, and illustrated essay titles include «The epidemiology of violence» and «Observations on fatal injuries to the brain stem and / or upper cervical spinal cord».

The clinical trial is designed to assess safety and activity of escalating doses of the special cells (AST - OPC1) for individuals with a complete cervical spinal cord injury.

The trial involves testing three escalating doses of AST - OPC1 in patients with subacute, C5 - C7, neurologically - complete cervical spinal cord injury.

In the near future, we could use this information to allow cognitive control of neural prosthetics in patients with ALS or severe cervical spinal cord injury,» said Adam Sachs, neurosurgeon and associate scientist at The Ottawa Hospital and assistant professor at the University of Ottawa Brain and Mind Research Institute.

Anatomical studies confirmed the importance of the right rehabilitation schedule: Depending on the therapeutic design, different patterns of new nerve fibers that sprouted into the cervical spinal cord from the healthy part of the brain and thus aid functional recovery to varying degrees were apparent.

These stroke - related alterations in the cervical spinal cord indicate pervasive and long - lasting BSCB damage that would severely affect spinal cord function, wrote the researchers, adding that the widespread microvascular impairment in the gray and white matter of the cervical spinal cord aggravated motor neuron deterioration and had the potential to cause motor dysfunction.

The researchers, who evaluated the BSCB in test animals at seven and 30 days after stroke modeling, found that ischemic stroke damaged the gray and white matter in the cervical spinal cord on both sides of the spinal column, based on analysis of electron microscope images.

Infection with Bb led to many histopathologic findings in infected animals not treated with dexamethasone, such as leptomeningitis, vasculitis, focal inflammation in the brain and spinal cord, and necrotizing focal neurodegeneration and demyelination in the cervical spinal cord.

Shown here is: axillary lymph node hyperplasia and histiocytosis - 200X (A) and Bb antigen (D) in untreated animal IN16; cervical spinal cord, focal inflammatory lesion - 200X (B) and Bb antigen (E) from treated animal IH11; and a focal area of mononuclear inflammation in the myocardial interstitium - 1000X (C) and Bb antigen (F) from untreated animal IN05.

«In the near future, we could use this information to allow cognitive control of neural prosthetics in patients with ALS or severe cervical spinal cord injury.»

This consisted of (i) preservation of the size of MN (SI Fig. 8 d and e); (ii) preservation of MN number and size in those areas [i.e., cervical spinal cord (SI Fig. 9) or the nucleus ambiguous (SI Fig. 10)-RSB-, which degenerate later compared with lumbar lamina IX (23, 24); (iii) decreased astrocytosis (SI Fig. 11); and (iv) decreased alpha - synuclein, ubiquitin, and SOD1 aggregation (see SI Fig. 6 and Discussion in SI Text).

An even newer theory is that fibromyalgia may be related to compression of the cervical spinal cord, which can lead to sleep disruptions as well as widespread pain.

Several wide syrinxes can be seen in the cervical spinal cord (in white)

T2 and T1 weightened midsagital and transversal images of the foramen magnum, caudal occipital fossa and cervical spinal cord will show syringomyelia.

The Arkansas Veterinary Surgery Center performs a Cervical ventral slot procedure if the disc is in the cervical spinal cord area.

In 2013, a 22 - month - old child from Arizona recovered after surgical extraction of a gravid female O. lupi nematode from around her cervical spinal cord.

Affected dogs show corresponding gross lesions in the cervical spinal cord white matter that may extend to the thoracic spinal cord, as well as to the brain; peripheral nerve and muscle biopsies are unremarkable.

It has become customary to use MR to image the brain and cervical spinal cord in dogs suspected of having CLM and syringomyelia.

When paralysis is present the most likely areas of the brain to be affected are the brain stem, but the cervical spinal cord can also sometimes be involved in the disease process.

As the disease progresses, lesions will also appear in the lumbosacral and cervical spinal cord, and clinical signs will follow this progression.

The spine is divided into distinct regions: the cervical spinal cord, the thoracic spinal cord, the lumbar spinal cord, the sacral spine, and the coccygeal region.