Sentences with phrase «cessation of treatment»

For example, up - regulated influx transporters (OCT3 and OCTN1) localized at the apical membranes of Sertoli cells could mediate the transport of the drug compound 9 from the lumen into the basolateral compartment of Sertoli cells, where the up - regulated efflux transporters (ABCB1 / p - glycoprotein, ABCB8, ABCB9, ABCC5, and ABCC10) could then transport the drug out of Sertoli cells against a concentration gradient, resulting in enhanced efficiency of recovery upon cessation of treatment.

These were as follows: diarrhoea (four dogs; severe enough to warrant cessation of treatment in one dog); vomiting (four dogs); fever, lethargy and cystitis (one dog); an inflamed footpad and vomiting (one dog); and diarrhoea, vomiting and lethargy (one dog).»

To begin to explore possible molecular mechanisms by which longer exposure to a drug might result in a more rapid recovery following cessation of treatment, we made note of a study reporting changes in the levels of expression of efflux and influx membrane transporters in testes after oral administration of adjudin (27).

It is unknown whether any effect of SPINRAZA on growth would be reversible with cessation of treatment.

They concluded that patients with PMS can be treated successfully with Vitex agnus - castus extract, as indicated by clear improvement in the main effect parameter during treatment and the gradual return after cessation of treatment.

Skeletons of dead mites do not refract intense light as well as live mites (FIGURE 10), and this can lead to a false - negative interpretation that may result in premature cessation of treatment and recurrence of disease.2, 4

In the present study, we provide evidence that inhibition of the RARs at a very low daily dose (1.0 mg / kg) for a treatment period of up to 16 weeks consistently produced male sterility that was reversible upon cessation of the treatment.

Once it is established that a patient is competent and has voluntarily chosen the cessation of a treatment, the doctor and the hospital must obey.

In some cases, the reduction in heart function is temporary and cessation of the treatment and / or the addition of heart medicines can improve function.

Women who have IVF / ICSI infertility treatments have a 29 % chance of conceiving naturally within six years of the cessation of treatments.