Sentences with phrase «challenging because»

See full infographic: WEB PDF © NOVIE STUDIO, 2016, ALL RIGHTS RESERVEDEstimating when a HAR evolved is challenging because these calculations rely on comparisons with genomes from hominins that split off from our ancestors at different times in the past.

«Taking a picture of an exoplanet is extremely challenging because the star is much brighter than the planet, and the planet is very close to the star,» says Ben Mazin, lead researcher on the team.

Designing primers against genomic DNA to amplify the gRNA targets was challenging because you're limited by the sequence of the human genome.

Allogeneic cell therapies involving primary cell types such as bone marrow mesenchymal stromal / stem cells (BM - MSCs), hematopoietic stem and progenitor cells (HSPCs), and T and natural killer (NK) cells for immunotherapy applications are especially challenging because of the vigorous process of screening...

Realizing coherent spin — photon coupling is challenging because of the small magnetic - dipole moment of a single spin, which limits magnetic - dipole coupling rates to less than 1 kilohertz.

«Today, making discoveries from cancer genomic data is challenging because diverse research groups analyze different cancer datasets using various methods that are not easily comparable,» said GDC principal investigator Robert Grossman, professor of medicine and director of CDIS at UChicago.

Even with those in hand, accurate identification of de novo mutations is challenging because they're so exquisitely rare.

Learning the intricate inner workings of clouds is challenging because they are constantly changing and interact with the environment in many complex ways.

Treatment that targets the DNA in HIV - infected cells has been challenging because the persistent, incurable human immunodeficiency virus is able to insert its own DNA into the DNA of any infected cell while disabling that cell's ability to die to save other cells from a viral invasion.

«Detecting the Rayleigh signal is challenging because the frequency range where Rayleigh scattering has the biggest effect is contaminated by «noise» and foregrounds, such as galactic dust,» lead author Elham Alipour said.

Understanding the basis of psychiatric disorders has been extremely challenging because there are many genetic variants that may increase risk but are insufficient to cause disease.

Elucidating functions of commensal microbial genes in the mammalian gut is challenging because many commensals are recalcitrant to laboratory cultivation and genetic manipulation.

«Diagnosing primary adrenal insufficiency remains challenging because many of the symptoms are associated with a variety of health conditions,» said Stefan R. Bornstein, MD, PhD, of the Universitätsklinikum in Dresden, Germany, and King's College in London, U.K., and chair of the task force that authored the guideline.

Treatment of brain tumors is particularly challenging because regulatory T - cells accumulate in brain tumors and suppress an immune attack.

Performing transition metal chemistry with pyridine has proven challenging because it can «poison'the nickel catalyst, essentially binding to the nickel such that the reaction can not move forward.

Determining the convection properties of most evolved and supergiant stars, such as the size of granules, has been challenging because their surfaces are frequently obscured by dust.

«It's challenging because the bees can fly pretty fast.»

«In addition, we're finding that diagnosing reading difficulties with these kids is challenging because we're trying to pinpoint how much impact instruction has on them,» Orosco said.

Properly diagnosing Lyme disease can at times be challenging because of the limitations of the current laboratory test, particularly during the early stages of disease.

Understanding its molecular causes and risk factors has been challenging because most cases develop sporadically without inherited genetic mutations, and because of the gradual progression of symptoms over the course of disease.

«It's challenging because there isn't a lot of intuition on how to utilize the full potential of this technology.

Earlier studies revealed the individual components that make up the BMC shell, but imaging the entire organelle was challenging because of its large mass of about 6.5 megadaltons, roughly equivalent to the mass of 6.5 million hydrogen atoms.

Doing this type of study on cells in brain tissue has been challenging because the cells are densely packed and intimately intertwined.

Focusing the entire visible spectrum and white light — combination of all the colors of the spectrum — is so challenging because each wavelength moves through materials at different speeds.

«The field is very challenging because there are so many questions to ask,» she says.

Amino acids that don't usually exist in nature have been integrated into the proteins of bacteria (see main story) and fruit flies, but mammals had proved more challenging because they are larger and more complex.

What's more, recruiting medical workers to help with deliveries would be challenging because they are scared of being exposed to patients» blood, even when the latter are not symptomatic of Ebola, she says.

However, developing RNAi therapies has proven challenging because it is difficult to deliver large quantities of siRNA to the right location without causing side effects in other tissues or organs.

The technique of using sodium ions in the body as a biomarker for imaging is very challenging because of the lower detectability of the sodium signal in biological tissue by currently available MRI scanners.

Clean - up remains challenging because high radioactiviity prevents workers from staying too long near the reactors.

«We had to use the best telescope in the world under the best atmospheric conditions, and we had to set up the proper team — but most of all this measurement was really challenging because of the faintness of the source.»

The technique is challenging because a planet's atmospheric signal accounts for only one part in 1,000 of the star's light.

Reducing the disease burden by reducing open defecation is extremely challenging because, due to villagers» ideas about purity, pollution and caste, most people reject affordable latrines.

The problem is particularly challenging because mice make only one form of apoE, which only partly resembles human apoE.

Imaging detections are challenging because of the combined effect of small angular separation and large luminosity contrast between a planet and its host star.

In nonelderly patients requiring valve replacement, deciding between bioprosthetic and mechanical prosthetic valves is challenging because long - term survival and other outcomes have not been well defined, according to background information in the article.

Tracking freshwater plumes post-Sandy was challenging because the region was extremely cloudy for several days, which made clear satellite images hard to come by, Kohut said.

«The study was incredibly challenging because, to study bacterial cofactors of HIV risk, the team needed to identify samples collected just prior to HIV acquisition,» she said.

Studying aging and its associated diseases has been challenging because existing vertebrate models (e.g., mice) are relatively long lived, while short - lived invertebrate species (e.g., yeast and worms) lack key features present in humans.

«Determining exactly how many mutations occur during the development of the child has been challenging because conventional genetic sequencing is not sensitive enough to reliably identify post-zygotic mutations,» he will say.

I mean, not every zebra of course have, [having] seen many lions eating zebras — but enough zebras do survive, so that their population continues on and that's pretty much the same down with human beings there, though of course in recent years it has gotten a little more challenging because we've become much more cunning and technologically empowered predators than we were before.

This experience is much less challenging because I overcame many of its pitfalls as an undergrad.

«Those experiments will probably be quite challenging because of the high - frequency fields involved, but their outcome should finally tell us whether it is a radical - pair mechanism or not, and if it is, what the radicals are,» Hore says.

It was challenging because he knew very few of the basic biology tenets that support genetics.

The fabrication was «quite challenging because the mechanical resonators are essentially three - dimensional structures... and qubits are wires on silicon chips, and they're very flat,» O'Connell says.

I'm reacting to your question about the poll, which showed things more challenging because it is in fact a split ticket scenario.

Moderate to severe inverted nipples can be more challenging because you may need to stimulate your nipple to draw it out before feedings.

Choosing a good stroller for twins can be sometimes challenging because unlike a single stroller, strollers for twins are sometimes bulkier and heavier.

As I mentioned before, sleep coaching or behavioral shaping (especially if it involves crying) during 4 - 5 months could be more challenging because your baby may take up to 6 months to develop the needed skills.

Choosing two names can be challenging because not only do twin moms and dads want to find names that are unique and meaningful, they also want to find names that fit well in a pair and flow off the tongue — without sounding too cheesy.