Sentences with phrase «change cell behavior»

It is an enormously complicated and interdependent set of controls, still poorly understood to be sure, but the ability to change protein levels is in principle the ability to change cell behavior.

Other researchers have tried changing cell behavior by creating protein switches from scratch, but Lim's approach — mixing and matching naturally existing proteins — may be more versatile and practical: «It can be useful as a biotechnology device or for repairing cells in humans.

Not exact matches

When behavior is successful our cells become finely tuned to what the animal was learning at the time while a failure shows little change in the brain or improvement in the monkey's behavior.

Electromagnetic signals from cell phones can change your brainwaves and behavior.

In cancer cells, the protein networks that control the behavior are changed in such a way as to cause the cells to lose control and break away — a mutated skin cell, for instance, might then migrate into the bloodstream.

The Campàs lab is studying several of these questions, including how limbs are built and how mechanical changes in tumors affect the behavior of malignant cells and the growth of the tumor.

Because neural crest cells contribute to so many tissues in the body, altering their function could change an animal's behavior, appearance and biology, the researchers reasoned.

We thought that if viruses could bind to receptors in these spaces and change how brain cells normally communicate, the virus could change behavior of the infected animal.»

The Molecular Sciences Institute in Berkeley, California, combines genomic experimentation and computer modeling to predict the behavior of cells and organisms in response to genetic and environmental changes.

The researchers used genotyping to ascertain that mating, rather than just «stickiness» or cell fusion, was occurring, confirming a change from asexual to sexual behavior.

Even short - term blockages of this kind can lead to remarkable changes in the auditory system, altering the behavior and structure of nerve cells that relay information from the ear to the brain, according to a new University at Buffalo study.

Exosomes transport small pieces of genetic material, called microRNAs, that enable cells to communicate with neighboring cells to change their behavior.

At the core of this cell behavior is how the loss of that single gene changes activation levels of dozens of other genes, suppressing genes associated with metastatic disease and increasing activity of genes linked to normal tissue.

The research suggests that reducing production of the protein, called myoferlin, affects cancer cells in two primary ways: by changing the activation of many genes involved in metastasis in favor of normal cell behavior, and by altering mechanical properties of cancer cells — including their shape and ability to invade — so they are more likely to remain nested together rather than breaking away to travel to other tissues.

As a factor becomes more concentrated in a cell, it will begin to activate genes that it has less intrinsic affinity for, potentially changing the cell's behavior.

So over time, changes in the cytoskeleton form the shape and behavior of cells and, ultimately, the structure and function of the organism as a whole.

However, when chronic inflammation occurs in a blood vessel — typically in response to diabetes, high cholesterol and cigarette smoking — the smooth muscle cells in the walls of arteries change their behavior.

The teams suction - cupped a cell - phone sized device called a Dtag to study how fishing lines changed the whale's diving and swimming behavior.

Two different inherited genetic variations in two different families of children with ASD «converged» to produce the same changes in nerve function and behavior, the researchers report in EBioMedicine, a new online translational medicine journal published by editors at The Lancet and Cell Press.

The study recently published in «Cell Stem Cell» also shows that signals secreted by the choroid plexus dynamically change during aging which affects aged stem cell behavCell Stem Cell» also shows that signals secreted by the choroid plexus dynamically change during aging which affects aged stem cell behavCell» also shows that signals secreted by the choroid plexus dynamically change during aging which affects aged stem cell behavcell behavior.

The research team led by Prof. Fiona Doetsch at the Biozentrum of the University of Basel has now shown that the choroid plexus is a key component of the stem cell niche, whose properties change throughout life and affect stem cell behavior.

In addressing the first question, the study showed that the brain's immune cells, microglia, which are known to become activated by LPS exposure as well as in most brain injuries and diseases, begin spewing out pro-inflammatory factors that change astrocytes» behavior.

Those data were then combined with information about functional changes in cell behavior to develop a nanomechanical profile, or phenotype, for specific cellular states.

The immediate application of the research, Sinha explains, is in helping scientists pinpoint important changes in cell behavior.

They target particular cells and change their behavior.

When they put stem cells into this viscoelastic microenvironment and tuned the rate at which the gel relaxed, they observed dramatic changes in the behavior and differentiation of the cells.

The Purkinje cells, a class of neurons located in this region, are a major site of information integration that regulate changes in neural connections caused by varying factors such as behavior, environment, and emotions.

Researchers at Kumamoto University added VEGF to undifferentiated ES cells and tracked the behavior of the entire genome and epigenome changes over time in vitro.

It may, for example, partly account for the differences in brain structure and behavior between identical twins, and could even affect thought processes by subtly influencing the changes in nerve cell connections that occur with experience.

«And the change in the phase transition behavior changes the biology of the cell.»

The rescue of memories, which changed both the structure of neurons as well as the behavior of mice, was achieved using optogenetics, a method for manipulating genetically tagged cells with precise bursts of light.

Researchers from Melbourne's Walter and Eliza Hall Institute have discovered how a common parasite hijacks host cells and stockpiles food so it can lie dormant for decades, possibly changing its host's behavior or personality in the process.

How is it that cells can change their behavior based on signals from their neighbors, or even cells in entirely different parts of the body?

«And the advantage is that you don't have to cool the entire cell, which could kill it or change its behavior.»

Mycoplasma compete with host cells for nutrients and can alter expression of receptors, ion channels, and growth factors resulting in changes to the cell line's growth and behavior.

KLF4: Selectively lowering levels of klf4 in smooth muscle cells in blood vessel walls causes beneficial changes in the behavior of these cells.

Further down the road I see a lot of potential for us to be able to change the age - related behavior of cells.

Biocellion is being used to model a variety of biological system behaviors, such as biofilm formation and wrinkling, microbial growth dynamics in complex soil structure, brain tumor growth and invasion, formation of complex bacterial colonies, and changes in blood vessels and skin cells.

In order to test whether the particles could change the behavior of cells, the team injected a sample onto cultured rat dorsal root ganglia neurons, which are found in the peripheral nervous system.

These methods led to seminal discoveries linking changes in motor behavior in Parkinson's disease with the inability of specific brain cells to be modified.

The morphological changes manifested in the cell types linked to larger toepads exemplify cell type differentiation that must be controlled by the physiology of reproduction and properly timed nutrient - dependent reproductive sexual behavior, which probably occurs near the location of the higher perches.

To a small but growing number of physicists, however, the shape - shifting and behavior changes in cancer cells evoke not an errant genetic program but a phase transition.

We propose that the age - related decline in the regenerative behavior of glial cells is caused by loss of cell - to - cell communication and changes in the internal gene expression of glia cells.

«Our ongoing project aims to elucidate how cells recognize temperature or cellular events caused by the temperature changes and control the expression of DESAT1 to adapt the cellular processes and behaviors,» Umeda said.

According to Puzas, teriparatide significantly speeds up fracture healing by changing the behavior and number of the cartilage and the bone stem cells involved in the process.

Now, Salk Institute scientists studying roundworms suggest that, in both worms and humans, adolescent brains mature to stable adult brains by changing which brain cells they use to generate behavior.

SAN FRANCISCO, CA — Researchers at the Gladstone Institutes and University of California, San Francisco have shown that a loss of cells in the retina is one of the earliest signs of frontotemporal dementia (FTD) in people with a genetic risk for the disorder — even before any changes appear in their behavior.

''... we hypothesize that repeated stress - related allostatic overload may affect brain function at three basic levels: (a) at the cellular level, it may compromise proteostasis (e.g. tau protein), organelles homeostasis, and induce epigenetic changes in neuronal DNA; (b) at the tissue level it may affect intracellular communication (synaptic contacts), number of cells (reduction of neuronal density), composition of the extracellular matrix (accumulation of amyloid plaques), and neuroinflammation; (c) at the systemic levels it may alter the brain's regulation of behavior (cognitive decline).

They are the mechanism that allows estrogen and progesterone to change the behavior of our cells.

Another explanation is that CPS has no standards for in - school suspension rooms, so they are little more than holding cells that offer little or no education or counseling to help change behavior.