Sentences with phrase «change cycle at»

Not exact matches

«Tax reform does not change our capital return goals as we remain committed to returning at least $ 60 billion of capital in the current and next two CCAR cycles, subject to regulatory approval,» CEO Michael Corbat said in a press release on Tuesday.

That's exactly the kind of good news cycle that should precede an identity change, according to Wayne S. Rogers, Principal at Blade Creative Branding.

Once a month (or more or less frequently, depending on the length of your sales cycle), run your reports, read through them and make at least three changes based on what you find.

These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).

These risks include, in no particular order, the following: the trends toward more high - definition, on - demand and anytime, anywhere video will not continue to develop at its current pace or will expire; the possibility that our products will not generate sales that are commensurate with our expectations or that our cost of revenue or operating expenses may exceed our expectations; the mix of products and services sold in various geographies and the effect it has on gross margins; delays or decreases in capital spending in the cable, satellite, telco, broadcast and media industries; customer concentration and consolidation; the impact of general economic conditions on our sales and operations; our ability to develop new and enhanced products in a timely manner and market acceptance of our new or existing products; losses of one or more key customers; risks associated with our international operations; exchange rate fluctuations of the currencies in which we conduct business; risks associated with our CableOS ™ and VOS ™ product solutions; dependence on market acceptance of various types of broadband services, on the adoption of new broadband technologies and on broadband industry trends; inventory management; the lack of timely availability of parts or raw materials necessary to produce our products; the impact of increases in the prices of raw materials and oil; the effect of competition, on both revenue and gross margins; difficulties associated with rapid technological changes in our markets; risks associated with unpredictable sales cycles; our dependence on contract manufacturers and sole or limited source suppliers; and the effect on our business of natural disasters.

Factors that could cause or contribute to actual results differing from our forward - looking statements include risks relating to: failure of DBRS to rate the Notes at the anticipated ratings levels, which is a closing condition, or at all; changes in the financial markets, including changes in credit markets, interest rates, securitization markets generally and our proposed securitization in particular; the willingness of investors to buy the Notes; adverse developments regarding OnDeck, its business or the online or broader marketplace lending industry generally, any of which could impact what credit ratings, if any, are issued with respect to the Notes; the extended settlement cycle for the scheduled closing on April 17, 2018, which may exacerbate the foregoing risks; and other risks, including those described in our Annual Report on Form 10 - K for the year ended December 31, 2017 and in other documents that we file with the Securities and Exchange Commission from time to time which are or will be available on the Commission's website at www.sec.gov.

[16:00] Pain + reflection = progress [16:30] Creating a meritocracy to draw the best out of everybody [18:30] How to raise your probability of being right [18:50] Why we are conditioned to need to be right [19:30] The neuroscience factor [19:50] The habitual and environmental factor [20:20] How to get to the other side [21:20] Great collective decision - making [21:50] The 5 things you need to be successful [21:55] Create audacious goals [22:15] Why you need problems [22:25] Diagnose the problems to determine the root causes [22:50] Determine the design for what you will do about the root causes [23:00] Decide to work with people who are strong where you are weak [23:15] Push through to results [23:20] The loop of success [24:15] Ray's new instinctual approach to failure [24:40] Tony's ritual after every event [25:30] The review that changed Ray's outlook on leadership [27:30] Creating new policies based on fairness and truth [28:00] What people are missing about Ray's culture [29:30] Creating meaningful work and meaningful relationships [30:15] The importance of radical honesty [30:50] Thoughtful disagreement [32:10] Why it was the relationships that changed Ray's life [33:10] Ray's biggest weakness and how he overcame it [34:30] The jungle metaphor [36:00] The dot collector — deciding what to listen to [40:15] The wanting of meritocratic decision - making [41:40] How to see bubbles and busts [42:40] Productivity [43:00] Where we are in the cycle [43:40] What the Fed will do [44:05] We are late in the long - term debt cycle [44:30] Long - term debt is going to be squeezing us [45:00] We have 2 economies [45:30] This year is very similar to 1937 [46:10] The top tenth of the top 1 % of wealth = bottom 90 % combined [46:25] How this creates populism [47:00] The economy for the bottom 60 % isn't growing [48:20] If you look at averages, the country is in a bind [49:10] What are the overarching principles that bind us together?

We believe that AbraPlata is now well positioned, and due to our recently oversubscribed Offering, well capitalized to take advantage of the converging factors of renewed interest by investors in the mining sector and the positive changes in Argentina at the start of a new economic / political cycle.

Many factors could cause BlackBerry's actual results, performance or achievements to differ materially from those expressed or implied by the forward - looking statements, including, without limitation: BlackBerry's ability to enhance its current products and services, or develop new products and services in a timely manner or at competitive prices, including risks related to new product introductions; risks related to BlackBerry's ability to mitigate the impact of the anticipated decline in BlackBerry's infrastructure access fees on its consolidated revenue by developing an integrated services and software offering; intense competition, rapid change and significant strategic alliances within BlackBerry's industry; BlackBerry's reliance on carrier partners and distributors; risks associated with BlackBerry's foreign operations, including risks related to recent political and economic developments in Venezuela and the impact of foreign currency restrictions; risks relating to network disruptions and other business interruptions, including costs, potential liabilities, lost revenues and reputational damage associated with service interruptions; risks related to BlackBerry's ability to implement and to realize the anticipated benefits of its CORE program; BlackBerry's ability to maintain or increase its cash balance; security risks; BlackBerry's ability to attract and retain key personnel; risks related to intellectual property rights; BlackBerry's ability to expand and manage BlackBerry ® World ™; risks related to the collection, storage, transmission, use and disclosure of confidential and personal information; BlackBerry's ability to manage inventory and asset risk; BlackBerry's reliance on suppliers of functional components for its products and risks relating to its supply chain; BlackBerry's ability to obtain rights to use software or components supplied by third parties; BlackBerry's ability to successfully maintain and enhance its brand; risks related to government regulations, including regulations relating to encryption technology; BlackBerry's ability to continue to adapt to recent board and management changes and headcount reductions; reliance on strategic alliances with third - party network infrastructure developers, software platform vendors and service platform vendors; BlackBerry's reliance on third - party manufacturers; potential defects and vulnerabilities in BlackBerry's products; risks related to litigation, including litigation claims arising from BlackBerry's practice of providing forward - looking guidance; potential charges relating to the impairment of intangible assets recorded on BlackBerry's balance sheet; risks as a result of actions of activist shareholders; government regulation of wireless spectrum and radio frequencies; risks related to economic and geopolitical conditions; risks associated with acquisitions; foreign exchange risks; and difficulties in forecasting BlackBerry's financial results given the rapid technological changes, evolving industry standards, intense competition and short product life cycles that characterize the wireless communications industry.

Right now Abra is one wallet / one currency but we give you the ability to do a foreign currency conversion right in the app so you can change your currency any time you like (you do have to wait at least one block cycle for the exchange to settle.)

We can also state that when a major antitrust action is resolved after a long period of conflict, it is a sign that the social mood trend of at least Cycle degree is likely changing from bear to bull.

We can state further that when a major antitrust action takes place after a long period of non-action, it is a sign that the social mood trend of at least Cycle degree is likely changing from bull to bear.

Speaking in abstract terms about blank, amorphous «innocent lives» keeps us from confronting the reality that if most of these children are born at or near the poverty line, then the lives we are saving are more likely to be troubled ones, and if nothing changes, those lives will get caught in vicious cycles powered by poverty and systemic racism.

At Key Stage 3 (age 11 to 13 +, Years 7 to 9) schools have to teach: that fertilisation in humans and flowering plants is the fusion of a male and a female cell; about the physical and emotional changes that take place during adolescence; about the human reproductive system, including the menstrual cycle and fertilization; how the foetus develops in the uterus, including the role of the placenta.

Since the birth of Christ and Christianity, the world has cycled through numerous periods of change; Christians existing in these periods have been both persecuted and at times privileged.

This would be that point prior to as you said «At any point in the cycle of nothingness of eternity, something will happen to change it into something to initiate time».

At any point in the cycle of nothingness of eternity, something will happen to change it into something to initiate time.

Pack a nightlight to make middle - of - the - night diaper changes easier, and so that you can avoid turning on bring lights at night and disrupting sleep cycles.

Wow, frankly I'm amazed that any mother remembers WHAT she did with her kid at seven weeks, other than the feed»em / nap»em / change»em cycle.

Night waking can be due to hunger, but it can also be due to teething or «reverse cycling,» (when babies eat less during the day and more at night, often due to a change in routine like a return to work, or distracted behavior during the day).

Park District director Jerry Handlon said the agency will immediately post no - cycling signs at the natural area's three entrances informing residents of the ordinance change, which formally will take effect Oct. 21.

But all that you have to do is to look at the reason why after every election cycle people cry out for change.

The Board of Elections said you can change your party affiliation at any time, but it won't go into effect until the next election cycle, which some groups called unfair.

«Every cycle, for the past several cycles, Democrats have talked about how this is the cycle when it's going to change, this is the year they're going to make gains at the state level,» said Matthew Walter, president of the Republican State Leadership Committee, a group that assists GOP state legislative candidates across the country.

This training also seeks to support the FOISECON in order to build their capacity to conduct free and credible elections at the local government levels and how well - implemented electoral process can bring about peaceful change of power and improve their leadership skills and take on board means for preventing or mitigating the escalation of electoral violence and conflict throughout the respective electoral cycle.

The elderly, disabled and terminally ill are today protected by the law, but in an age when the call upon the state budget to care for the elderly is high, and at a trying time in the economic cycle, how safe would people feel if that law were to change?

Let's dedicate $ 100 million to transform every failing school in New York into a comprehensive, holistic, full - service community school and change the basic education system in this state and stop the cycle of incarceration in this state and paying for problems, rather than stopping the problems at an early age.

THE size of a woman's brain changes throughout her menstrual cycle, with some areas growing by as much as 2 per cent in the run - up to ovulation, when women are at their most fertile.

External forces like abrupt changes in solar output or volcanism could have started and stopped the cycle, says Trouet, who hopes to pinpoint the trigger at a climatology workshop in May.

Looking at shifts in Manley's winter temperatures from year to year, he says, gives a good reading of important natural cycles that influence climate, such as changes in ocean circulation like the North Atlantic Oscillation.

Meanwhile, Alexander Schier at the University of Harvard and colleagues measured how various drugs changed the sleep - wake cycles of zebrafish larvae (Science, DOI: 10.1126 / science.1183090).

Even if you are trying to change hundreds or thousands of genes at once, after a few cycles in the machine, a good proportion of the cells should have all the desired changes.

Levels of CO2 also shift seasonally, changing as leaves drop in fall and ice forms in winter or as animals go through their life cycles, and even daily, rising at night due to temperature changes and algae's inability to photosynthesize at night.

Absence is not a manifesto for change or a look at hard science backing his claims; journalist Harris simply wants to start a discussion about how email, 24 - hour news cycles and the Twittersphere have eroded our appreciation for stillness.

The climatic change at issue is known as the Atlantic Multidecadal Oscillation (AMO), a periodic cycle of warming and cooling of surface temperatures in the North Atlantic.

A McGill - led international research team has now completed the first global study of changes that occurred in a crucial component of ocean chemistry, the nitrogen cycle, at the end of the last ice age.

Fluctuations in these cycles reflect trees» responses to annual variability in climate, and hint at how they will fare in the face of long - term climate change.

«Future climate change may be underestimated,» says study coauthor Yujie He, a carbon cycle researcher at the University of California, Irvine.

«We can use the inclusions to date different parts of an individual diamond, and that allows us to potentially look at how the processes that formed diamonds may have changed over time and how this may be related to the changing carbon cycle on Earth.»

For the first time, this study allowed researchers to analyse the effects of the climate change on the forest nutrient cycles, and states that Pyrenean forests can register these episodes chemical mark at a global scale (for instance, volcanic eruptions in remote areas) and the effects of gas emissions into the atmosphere since the Industrial Revolution.

«We determined the weather on these alien worlds by measuring changes as the planets circle their host stars, and identifying the day - night cycle,» said Lisa Esteves, a PhD candidate in the Department of Astronomy & Astrophysics at the University of Toronto, and lead author of the study published today in The Astrophysical Journal.

«We started from scratch and she wanted to know glacial cycles, rate of deforesting, solar variability — all of the issues that could impact climate and why I think that humans are the main driver of climate change,» he explained afterward at a debriefing with colleagues at a pub on Capitol Hill.

«Climate change strikes at the weak point in the cycle or life history for each different species,» Oliver said.

Their results showed that changes in key water - stress variables are strongly modified by vegetation physiological effects in response to increased CO2 at the leaf level, illustrating how deeply the physiological effects due to increasing atmospheric CO2 impact the water cycle.

Hayes believes that a fundamental change in the carbon cycle around 570 million years ago made younger rocks better at turning dead organisms into oil.

If the change to the carbon cycle really was instantaneous, a comet is a good candidate, agrees Dallas Abbott at Columbia University in Palisades, New York — although it would have to have been large to have such a dramatic effect.

The field study examined a change in the so - called restart provision, which allows drivers to start a new duty cycle after going off duty for at least 34 hours.

They also looked at changes in Martian gravity — which is about one - third that of Earth's gravity — over 11 years (the same as the sun's cycle of activity).

We recently extended this record to approximately 120,000 years BP in order to track vegetation change over a full glacial cycle at millennial to orbital timescales.

In a paper published in Science Advances, he proposes that mass extinction occurs if one of two thresholds are crossed: For changes in the carbon cycle that occur over long timescales, extinctions will follow if those changes occur at rates faster than global ecosystems can adapt.