Sentences with phrase «change effects over»

I also hope that this research can be a model for future studies that continue to investigate climate change effects over time and space using the fossil record.

Not exact matches

Important factors that could cause actual results to differ materially from those reflected in such forward - looking statements and that should be considered in evaluating our outlook include, but are not limited to, the following: 1) our ability to continue to grow our business and execute our growth strategy, including the timing, execution, and profitability of new and maturing programs; 2) our ability to perform our obligations under our new and maturing commercial, business aircraft, and military development programs, and the related recurring production; 3) our ability to accurately estimate and manage performance, cost, and revenue under our contracts, including our ability to achieve certain cost reductions with respect to the B787 program; 4) margin pressures and the potential for additional forward losses on new and maturing programs; 5) our ability to accommodate, and the cost of accommodating, announced increases in the build rates of certain aircraft; 6) the effect on aircraft demand and build rates of changing customer preferences for business aircraft, including the effect of global economic conditions on the business aircraft market and expanding conflicts or political unrest in the Middle East or Asia; 7) customer cancellations or deferrals as a result of global economic uncertainty or otherwise; 8) the effect of economic conditions in the industries and markets in which we operate in the U.S. and globally and any changes therein, including fluctuations in foreign currency exchange rates; 9) the success and timely execution of key milestones such as the receipt of necessary regulatory approvals, including our ability to obtain in a timely fashion any required regulatory or other third party approvals for the consummation of our announced acquisition of Asco, and customer adherence to their announced schedules; 10) our ability to successfully negotiate, or re-negotiate, future pricing under our supply agreements with Boeing and our other customers; 11) our ability to enter into profitable supply arrangements with additional customers; 12) the ability of all parties to satisfy their performance requirements under existing supply contracts with our two major customers, Boeing and Airbus, and other customers, and the risk of nonpayment by such customers; 13) any adverse impact on Boeing's and Airbus» production of aircraft resulting from cancellations, deferrals, or reduced orders by their customers or from labor disputes, domestic or international hostilities, or acts of terrorism; 14) any adverse impact on the demand for air travel or our operations from the outbreak of diseases or epidemic or pandemic outbreaks; 15) our ability to avoid or recover from cyber-based or other security attacks, information technology failures, or other disruptions; 16) returns on pension plan assets and the impact of future discount rate changes on pension obligations; 17) our ability to borrow additional funds or refinance debt, including our ability to obtain the debt to finance the purchase price for our announced acquisition of Asco on favorable terms or at all; 18) competition from commercial aerospace original equipment manufacturers and other aerostructures suppliers; 19) the effect of governmental laws, such as U.S. export control laws and U.S. and foreign anti-bribery laws such as the Foreign Corrupt Practices Act and the United Kingdom Bribery Act, and environmental laws and agency regulations, both in the U.S. and abroad; 20) the effect of changes in tax law, such as the effect of The Tax Cuts and Jobs Act (the «TCJA») that was enacted on December 22, 2017, and changes to the interpretations of or guidance related thereto, and the Company's ability to accurately calculate and estimate the effect of such changes; 21) any reduction in our credit ratings; 22) our dependence on our suppliers, as well as the cost and availability of raw materials and purchased components; 23) our ability to recruit and retain a critical mass of highly - skilled employees and our relationships with the unions representing many of our employees; 24) spending by the U.S. and other governments on defense; 25) the possibility that our cash flows and our credit facility may not be adequate for our additional capital needs or for payment of interest on, and principal of, our indebtedness; 26) our exposure under our revolving credit facility to higher interest payments should interest rates increase substantially; 27) the effectiveness of any interest rate hedging programs; 28) the effectiveness of our internal control over financial reporting; 29) the outcome or impact of ongoing or future litigation, claims, and regulatory actions; 30) exposure to potential product liability and warranty claims; 31) our ability to effectively assess, manage and integrate acquisitions that we pursue, including our ability to successfully integrate the Asco business and generate synergies and other cost savings; 32) our ability to consummate our announced acquisition of Asco in a timely matter while avoiding any unexpected costs, charges, expenses, adverse changes to business relationships and other business disruptions for ourselves and Asco as a result of the acquisition; 33) our ability to continue selling certain receivables through our supplier financing program; 34) the risks of doing business internationally, including fluctuations in foreign current exchange rates, impositions of tariffs or embargoes, compliance with foreign laws, and domestic and foreign government policies; and 35) our ability to complete the proposed accelerated stock repurchase plan, among other things.

He made mashups of the old images blending in the present scenery, creating a ghost - like effect of reflecting back over 100 years to one of the key events that changed the city forever.

«One thing we do know is that over the course of the years we have had some macroprudential changes to how this system works and we are comfortable those changes have done a lot to make sure the most fragile or the most vulnerable of those in that borrowing space are in effect being protected or have been prevented from excessive borrowing,» he said.

Apple improved the original portrait mode a lot (which didn't change lighting effects) so I expect this will only improve over time.

The latest report from the International Panel on Climate Change, an intergovernmental group charged with researching the effects of carbon emissions, said at the end of September that climate change is unequivocal and that going forward, sea levels will rise at a faster rate than they have over the past 40 Change, an intergovernmental group charged with researching the effects of carbon emissions, said at the end of September that climate change is unequivocal and that going forward, sea levels will rise at a faster rate than they have over the past 40 change is unequivocal and that going forward, sea levels will rise at a faster rate than they have over the past 40 years.

Indeed, when one ponders the changes that the global economy has had to digest over the past 25 years, from the fall of the Iron Curtain to the flowering of the Internet - based economy to the entrance of 1.3 billion Chinese into the labor force, it would be surprising if the effects weren't felt by American workers.

Over the last two weeks, the world's politicians, businessmen, scientists and environmentalists have gathered in Paris to discuss one thing: how to save the world from the catastrophic effects of climate change.

These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).

However, on Wednesday the Senate Public Utilities Committee canceled plans to send Senate Bill 58 to the floor for a full chamber vote at least until next year over concerns about the effects of the bill's proposed changes.

Shares fell last week after Axios reported last Wednesday that Trump was considering changes to the retailer's tax treatment, in part because of anger over how Amazon has hurt the commercial real estate industry because of its negative effect on brick - and - mortar retailers.

But looking over recent decades, that change has been fairly smooth, and on a relative basis, the effect on valuations is far more modest than investors seem to assume.

Since a larger share of deposit rates are fixed than are loan rates, this will overstate the effect on cash flows over longer time horizons, though the extent of this bias has not necessarily changed over time in an obvious way.

Such risks and uncertainties include, but are not limited to: our ability to achieve our financial, strategic and operational plans or initiatives; our ability to predict and manage medical costs and price effectively and develop and maintain good relationships with physicians, hospitals and other health care providers; the impact of modifications to our operations and processes; our ability to identify potential strategic acquisitions or transactions and realize the expected benefits of such transactions, including with respect to the Merger; the substantial level of government regulation over our business and the potential effects of new laws or regulations or changes in existing laws or regulations; the outcome of litigation, regulatory audits, investigations, actions and / or guaranty fund assessments; uncertainties surrounding participation in government - sponsored programs such as Medicare; the effectiveness and security of our information technology and other business systems; unfavorable industry, economic or political conditions, including foreign currency movements; acts of war, terrorism, natural disasters or pandemics; our ability to obtain shareholder or regulatory approvals required for the Merger or the requirement to accept conditions that could reduce the anticipated benefits of the Merger as a condition to obtaining regulatory approvals; a longer time than anticipated to consummate the proposed Merger; problems regarding the successful integration of the businesses of Express Scripts and Cigna; unexpected costs regarding the proposed Merger; diversion of management's attention from ongoing business operations and opportunities during the pendency of the Merger; potential litigation associated with the proposed Merger; the ability to retain key personnel; the availability of financing, including relating to the proposed Merger; effects on the businesses as a result of uncertainty surrounding the proposed Merger; as well as more specific risks and uncertainties discussed in our most recent report on Form 10 - K and subsequent reports on Forms 10 - Q and 8 - K available on the Investor Relations section of www.cigna.com as well as on Express Scripts» most recent report on Form 10 - K and subsequent reports on Forms 10 - Q and 8 - K available on the Investor Relations section of www.express-scripts.com.

Over the long term they must effect these transfers, but they can not do so quickly enough to balance a change in the balance of payments.

This is because interest rate changes have their largest effect on inflation risk, while stronger macroprudential settings will lead to a higher quality of household indebtedness over time.

The combined effect of this uncertainty overhang — from global trade tensions to domestic debt growth to tax law changes to interprovincial disputes over east - west pipeline access — has weighed on Canadian investment activity.

The coincidence of the effects arising from the changes to the tax system and the Olympic Games in September will make interpreting developments in the economy, especially the monthly data, more difficult than usual over the near term.

The changes to the forecasts for inflation over the years to June 2000 and June 2001 (excluding the effect of the GST) appear to reflect current and prospective developments in oil and tobacco prices as well as a modest increase in the assessment of underlying inflationary pressures.

Over the past three decades we have seen an increase in insured damages, and it is up to all of us — the insurance industry, governments and citizens — to do our part in responding to the effects of climate change.»

The after - tax effect of the corporate alternative minimum tax change was to raise Walmart's Puerto Rican tax liability to over 90 % of its income.

Interestingly, if over the course of the forecast horizon, they go up and then revert back to where they are today, the effect on the return will actually be negative, because there will be no net change in valuation, but some of the ensuing dividends will have been reinvested at higher valuations than those available today.

«t's actually quite hard to figure out how much of the change in median household incomes over time is due to Simpson's Paradox - type composition effects»

Often these effects change over time — new information, new circ umstances, new beliefs.

If we could even effect in one percent of our readers a change - over from the conception of Space to the conception of Heaven, we should have made a beginning.

In The Philosopher's Pupil (1983) a man's life is changed by his vision of a flying saucer; a key episode in The Good Apprentice turns on what appears to be the effects of a love potion; a young girl in The Green Knight exerts an involuntary telekinesis over the stones that she has collected in her room; in the same novel the goodness of a man named Peter Mir (Mir meaning, in Russian, both «world» and «peace,» as several characters note) seems to be contagious, bringing sweet dreams and love to those with whom he comes in contact.

If the Earth really moved around the sun, the apparent positions of stars should change slightly over the course of a year, an effect called «stellar parallax,» and no parallax was seen.

Along the way I will describe some events that are virtually unknown about the televangelists gained power over the Federal Communication Commission — a power that has provided a unique opportunity for fundamentalist religion to effect cultural change during the past forty years.

Some have supposed that he changed God's attitude toward man or effected some alteration in the power of evil over the world.

Also there is evidence of molecular mechanisms in the cell membranes that can amplify small changes in the field to produce large changes in neural activity.13 On the other hand, earlier tests of Kohler's theory found that interference with electrical gradients over the cortex had no effect on behavioral measures (see note 11 for reference to these studies).

see what you have to understand about living in a real world — a world where god is just a story and not real — its a world based on scientific and physical laws that are proven to exist and their effects are measurable... us as humans, mere animals, hold no real power or control aside thru ingenuity which allows us to change our environment to suit us... stay with me here... at this point in human history we ceased to change to suit our environment and started changing it to suit us — thats destruction of the earth to suit one species — that should go over well...

In leading retreats and seminars over the years, I have had an opportunity to keep in touch with clergy spouses» changing perceptions of their position and its effects upon their lives.

Even * if * the bible (pick whichever version you like as a starting point) was not actually changed, as in a version 1 + was never released, christians only pay attention to the bits they like, so in effect, the bible and christian's adherence to it, have changed over the years.

Guidelines around infant feeding and allergy prevention have changed around the world over the last 18 - 24 months, reflecting new evidence that suggests early introduction of potentially allergenic foods may have a protective effect, especially -LSB-...]

This change has been in effect for just over two years, but it is important to note that methionine is the only synthetic amino acid permitted in livestock feed as it is essential for the growth and well being of the animal.

Knowing mid-season that there could be a change of manager could have a bad effect on the squad, causing unrest between the players that perhaps would prefer him to stay, over those that want change.

Maybe changing the face masks back to single bar would have an effect, but even then probably not because of the instinct the players have built up over the years of football training.

I see nobody in management with the strength of character to force Wenger to make changes - changes that will have the effect of diluting Wenger's control over everything Arsenal.

He said that 4 weeks ago he would never have said that, but having watched the way both teams have performed over these last 4 weeks, unless United have a drastic change of form, he can not see us getting more than 2 points from the games against Liverpool, Citeh, Chelsea and Spurs, which will in effect push us tumbling down the table.

Mortgage calculators are automated tools accessible over the internet and help determine the effect of changes to any of the mortgage loan components such as the interest rate, repayment amount, principal amount, etc..

The fathers are shown that in fact they can exercise a lot of control — over their own behaviour and their reactions to others and this can help them change their situation; it is empowering for them to act positively and to see the effect this has on their child and their relationship.

Although these processes will continue to change over time, parenting can have important positive effects even when children have inherited a genetic vulnerability to problematic behaviors.»

Individual growth curve models were developed for multilevel analysis and specifically designed for exploring longitudinal data on individual changes over time.23 Using this approach, we applied the MIXED procedure in SAS (SAS Institute) to account for the random effects of repeated measurements.24 To specify the correct model for our individual growth curves, we compared a series of MIXED models by evaluating the difference in deviance between nested models.23 Both fixed quadratic and cubic MIXED models fit our data well, but we selected the fixed quadratic MIXED model because the addition of a cubic time term was not statistically significant based on a log - likelihood ratio test.

This means that even small sleep changes, over time, will have significant negative effects.

Simply stimulating a baby with a fast changing view may achieve the effect of distracting it in the short term but too much imagery with no perspective can result in over stimulation of the baby.

It will in effect change the absolute power of parliament, the cornerstone of our constitution for over 300 years.

Despite the widespread public alarm over the effects of the new tax law's capping of state and local tax deductions at $ 10,000, that tax change had little effect on Schumer and Weinshall and the Gillibrands.

The new law goes into effect next year and keeps 16 - and 17 - year - old offenders from being tried in adult criminal court but Dinolfo says over the next few months, the county will work out how to fund the change.

Several of these changes will go into effect over the coming months.

Acting Inspector General of Police (IGP) David Asante - Apeatu effected his second changes in the service since he took over the helm of affairs.