One study in the Journal of Clinical Gastroenterology concluded prebiotics and probiotics «serve to elicit
changes in the gut microbiota composition that increase populations of purported beneficial gut bacterial genera.»
Recent studies indicate that
adverse changes in gut microbiota are associated with the development of type 1 diabetes, but little is known about the microbiota in children who have diabetes at an early age.
The study is important because it links diet to
changes in the gut microbiota as well as bile acid profile, opening the possibility that probiotics and bile acid receptor agonists may be useful for the prevention and treatment of hepatic inflammation and progression into advanced liver diseases such as cancer.
In one of the largest longitudinal studies of the microbiome to date, researchers from the Broad Institute of MIT and Harvard, Massachusetts General Hospital (MGH), and the DIABIMMUNE Study Group have identified a connection
between changes in gut microbiota and the onset of type 1 diabetes (T1D).
These calorie restriction -
induced changes in the gut microbiota are concomitant with significantly reduced serum levels of lipopolysaccharide - binding protein, suggesting that animals under calorie restriction can establish a structurally balanced architecture of gut microbiota that may exert a health benefit to the host via reduction of antigen load from the gut.»
However, it seems likely that
changes in our gut microbiota and their metabolic products are important in explaining the influence of diet on many aspects of health, says Harry Flint at the University of Aberdeen, UK.
«We found that even a single exposure to social stress causes
a change in the gut microbiota, similar to what is seen following other, much more severe physical stressors, and this change gets bigger following repeated exposures,» said Dr. Kim Huhman, Distinguished University Professor of Neuroscience at Georgia State.
Several studies have shown that Crohn's disease is characterized by microbial dysbiosis, a shift in the microbial populations inhabiting the gut, but it's difficult to unravel cause and effect:
A change in gut microbiota can cause inflammation, but the reverse can also occur.
«We were surprised at the extent and complexity of
the changes in the gut microbiota composition,» says Peterson.
Studies show that just two consecutive nights of too little sleep can lead to negative (and possibly long - term)
changes in your gut microbiota.
Within the study, there was no evidence of
a change in gut microbiota profile via consumption of the fermented product; however, more importantly, the fermentation of milk significantly alters bioactive peptides and other chemicals that are well capable of influencing central nervous system function [107 — 110].