Sentences with phrase «change in the region over»

Although the recent drought may have significant contributions from natural variability, it is notable that hydrological changes in the region over the last 50 years can not be fully explained by natural variability, and instead show the signature of anthropogenic climate change.

Not exact matches

These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).

As climate change and global warming open up the Arctic to greater human and commercial activity, international interest in accessing and exploiting the region's economic potential has risen dramatically over the past decade.

Buster People all around the world have experienced near death events... of all regions and non-believers... over all those people do not have the same experience but those that are religious see the after life in terms of their religion, but all have a spiritual experience that changes them... What I am curious is do these prove that Christians are correct..

Explore maps to get to know the region, create your own map and share it over the web, or use the data to advocate for change in your neighborhood.

Five years later, a lot has changed: Cuomo is presiding over casino openings in upstate communities, touting their construction as a part of a turnaround for a struggling region of the state.

Countries in this region consist of Burundi, Djibouti, Eritrea, Ethiopia, Kenya, Rwanda, Somalia, South - Sudan, Sudan, Tanzania, Uganda and Zanzibar Needing another seven votes to end Hayatou's long - standing reign in CAF, a key figure in Ahmad's think - tank, who has criss - crossed over 37 countries in the last weeks, campaigning for change in African football.

The Buffalo Billion is evolving - and a big reason for that is the changes that have happened in the Buffalo Niagara region over the past five years.

Sources with knowledge of the talks in Albany said that disputes remained over matters of time and space: the length of the period in which the change should be implemented, and the regions outside of New York City where the phase - in could occur at a slower rate due to a lower cost of living.

The results were fascinating: reflecting changes in policy and production of these chemicals in the different regions over time.

Arctic plants have retreated and advanced in their colonization of fertile regions with great speed and over vast distances as the climate changes

«Brain development and aging: New study reveals that brain signals in specific regions change over a lifespan in ways that might be important for maintaining flexibility.»

«Using a numerical climate model we found that sulfate reductions over Europe between 1980 and 2005 could explain a significant fraction of the amplified warming in the Arctic region during that period due to changes in long - range transport, atmospheric winds and ocean currents.

The northern polar region's climate has materially changed over the past five years, a team of 121 scientists from 14 nations concludes in a December 1 Arctic report card.

The Hubble Space Telescope's new view of the Pillars of Creation, a star - forming region in the Milky Way, is giving scientists a close look at how this iconic cosmic structure has changed over time.

Future studies are needed to track changes in free water over longer time spans and in other brain regions and to determine what causes them.

For example, he says, although the new study found no overall change in the rate of melting at Totten Glacier over the last couple of decades, the large variability in melting rate within those decades warrants a much closer look at the region's complex topography, among other factors, in order to anticipate how the system could actually change in the future.

In particular, the modelers could now reproduce in detail the pattern of warming, changes in rainfall, etc. actually observed in different regions of the world over the past centurIn particular, the modelers could now reproduce in detail the pattern of warming, changes in rainfall, etc. actually observed in different regions of the world over the past centurin detail the pattern of warming, changes in rainfall, etc. actually observed in different regions of the world over the past centurin rainfall, etc. actually observed in different regions of the world over the past centurin different regions of the world over the past century.

To track changes in coastal waters and predict when seafood species in the region may be safe to consume, it will be necessary to establish a «temporal data set» — that is, to measure the levels and distributions of contaminant radionuclides at a given location over time, he says.

Using their satellite - based observations — recorded in 2007, 2010, and 2014 — they were able to estimate pore pressure changes at these wells over time, including during the 2012 magnitude 4.8 Timpson earthquake, the region's largest temblor.

Because the Daohugou Biota and the much better studied Jehol Biota are similar in preservational mode and geographic location, but separated by tens of millions of years, they give palaeontologists an outstanding, even unique, opportunity to study changes in the fauna of this region over a significant span of geological time and an important period in vertebrate evolution.

Researchers at the Helmholtz Centre for Environmental Research (UFZ) and the German Centre for Integrative Biodiversity Research (iDiv) have now revealed, on the basis of historical data, how plant diversity in the region of Halle an der Saale has changed in over 300 years of urbanization, and have also made predictions about the future.

Although more data are needed to fill gaps in the study, the authors say that the region connecting these sites faces rapid land - cover changes, which have severely increased over the last two decades, putting remaining stepping - stone habitats for jaguars at further risk.

The research concludes that for other changes, such as regional warming and sea ice changes, the observations over the satellite - era since 1979 are not yet long enough for the signal of human - induced climate change to be clearly separated from the strong natural variability in the region

Travelling between the stars for a hundred light years or so, we would find ourselves moving between regions where the density of gas changes a millionfold — more extreme than the difference between air and water — and with changes in temperature from just a few degrees above absolute zero to over a million degrees.

One of the report's lead authors, Monash University Professor Steven Chown, said key areas for scientific research in the region over the next two decades included looking at human impact on the region, understanding the evolution of Antarctic life, looking at the region's history, and the impact of climate change in the area.

The authors say that the rapid losses over the past two decades are a result of the sharp socio - economic changes the region experienced in this period, as previously untouched forests became criss - crossed by logging roads.

These corals could survive the next 100 years of climate change in the tropics, and kick - start the region's adaptation and evolution, thereby providing genetic material selected for heat resistance over 6 ky..

This has important implications for understanding and predicting changes in rainfall patterns over large populations across the Asia and Oceania regions.

The mutations in these regions represent key changes in human evolution over the last 40,000 years, after our ancestors first left Africa and were going global.

The changes in these regions can account for about 90 percent of the observed variation in the river's streamflow over the last century, with one to four months lead - time.

To date, Singer and Michaelides have used it to identify real climate change over a broad region, but they are in the process of coupling STORM to a runoff model to explore scenarios of climate change and how they might really affect the magnitude and the frequency of runoff.

To analyze how the frequency and significance of cranial modification changed over time, skeletal samples were collected from two mortuary sites in the Collagua region and submitted for radiocarbon measurement.

«The model is really flexible, and we are already starting to use it with fMRI data to understand how regions of the brain interconnect and change over time,» said Fuchen Liu, a Ph.D. student in the Department of Statistics and Data Science.

Due to the rising population and change in diet in some regions of the world over the past few decades, such as India and China, the demand for renewable resources increased and thus the pressure to produce as much food as possible.

This is expected to rise in many regions over the coming decades and could reduce or even negate the beneficial effects of higher CO2 (see Climate change warning over food production).

«The better resolution of the new map helps interpret how the crust of the planet changed over Mars» history in many regions.»

Here, we report on local and global changes in MHW characteristics over time as recorded by satellite and in situ measurements of sea surface temperature (SST) and defined using a quantitative MHW framework, which allows for comparisons across regions and events1.

The changes will happen over decades and either infrastructure changes will be made to accommodate the changes in the climate or people will gradually migrate to more favorable regions.

Nieves» team, which included participation from the Mediterranean Institute for Advanced Studies in Esporles, Spain, set out to detect decadal sea level changes over large U.S. coastal ocean regions.

They found that the likelihood of such extreme summers rose sharply in every region, cropping up at least 70 times more often in 2012 than in 1973 — a tenfold increase over the equivalent change looking at temperature alone.

Scorching summertime heat waves in Europe, Asia and North America, as well as extreme cold snaps in central Asia, have become more likely because of changes in the way air is flowing over those regions, a new study detailed in the journal Nature suggests.

But with recent advances in technology, we can now observe regions changing over time, for a deeper understanding of how stars form.

Prior to joining ECI, she completed her Ph.D. at Oregon State University, where she worked on the weather@home project over western US region, looking at drivers of extreme drought events in the US, future regional climate change projections over the western US, as well as investigating uncertainties due to internal variability and physical parameter perturbations.

Gaensler and Frail compared a 1993 VLA image of the region to one they made last year to measure the pulsar's change in position over a known time, and thus to calculate its speed.

More specifically, using digital scans of paper maps based on aerial imagery acquired by the U.S. Geological Survey, along with modern - day satellite imagery from a variety of platforms, the authors digitized a total of 49 maps and images from which they calculated changes in the terminus positions, ice speed, calving rates and ice front advance and retreat rates from 34 glaciers in this region over the period 1955 - 2015.

Over the past several years the online dating landscape changed dramatically, which is due in large part to the proliferation of free online dating sites for every region, area of interest, and type of.

Over the past several years the online dating landscape changed dramatically, which is due in large part to the proliferation of free online dating sites for every region, area of interest, and type of relationship sought.

Capcom announced this morning a demo for the game would arrive on August 10, and if you're unsure how to change your region on Switch Arekkz goes over it in this video.

With these realities in mind, APA worked to identify any districts in the southwest region that directly attributed substantive programmatic changes over the past several years to participation in TURN.