Sentences with phrase «change require further»

Many issues related to climate change require further study.

«The depth and speed of change required far exceeds the traditional change management process handled by HR departments.»

Even then, implementing the change requires further actions from large bureaucracies that are often invested in the status quo and may be hostile toward the reform.

Nonetheless, there are significant changes occurring within the electric system that could profoundly affect the economy and even national security, and as such, these changes require further study and investigation.

To understand the potential impacts of climate change requires further interactions, with agronomists, economists, demographic specialists, etc..

Not exact matches

But the OAS program requires reforms far greater than simply changing the age of eligibility.

These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).

Getting serious about credit card debt requires lifestyle changes, so we suggest taking it a step further than just using excess cash to pay off credit card debt.

Often it requires founders and chief executives to embrace a different approach to leadership, and make far - reaching changes in company structure and culture.

In addition, any testing by us conducted in connection with Section 404, or any subsequent testing by our independent registered public accounting firm, may reveal deficiencies in our internal controls over financial reporting that are deemed to be material weaknesses or that may require prospective or retroactive changes to our financial statements or identify other areas for further attention or improvement.

Clean meat will require much less land and will cause far less climate change than conventional meat.

Further, given the constantly changing goal - posts of a politics immersed in the emotivist chaos of competing psychological identities and subjective personal rights, why on earth would anyone now want to pursue a career that in five, ten, or fifteen years might be torn from them simply because somebody somewhere finds a right to goodness - knows - what in the Constitution — even, as in this case, when their job does not actually require them to be involved in said goodness - knows - what?

Thus far, it seems that the changes required of the process doctrine of God, while significant, are fairly minor.

It's far more reasonable to assume that clothing was invented in regions where climate changes made our low - hair bodies require it for survival.

A few lines further on he adds that «every organism requires an environment of friends, partly to shield it from violent changes, and partly to supply it with its wants.»

Change of a substantial nature would require political will of far - reaching range and significance.

But now if the individual, yes, if you, my listener, and I must admit to ourselves that we were far from living in this way, far from that purity of heart which truthfully wills but one thing; must admit to ourselves that the questions demanded an answer, and yet in another sense, in order to avoid any deception, did not require an answer, in that they were, if anything, charges against ourselves which in spite of the form of the question changed themselves into an accusation: then should the individual, and you, my listener, and I join together in saying, «Indeed our life is like that of most others»?

Some people were always so inclined not to hurt people, but others do require of themselves to change, but that change always comes from within as far as we can tell.

Indeed, it would require far more than a few changes in terminology and procedure for significant shifts to occur.

The rabbis, especially the school of Hillel, recognized that changing circumstances required new ways of applying the law; but, so far as I am aware, they did not pronounce any law contrary to God's original purpose.

Science dose not provide all the answers either but it looks for the answers and more importantly, when science gives an answer you do not have to except it on Faith, you are required to test it, question it and verify it until you are satisfied that the answer is right (at least right as far as we know now, it may change as we learn more).

A form of governance for cyberspace that takes equal entitlement to its resources seriously requires far reaching changes of the current political practices in such areas as development assistance, transfer of technology, intellectual property protection, and space cooperation.

Further, while television in some situations may stimulate an immediate radical change in attitude, emotions, or behavior, alone it lacks most of the capacities required to maintain the durability of that change or to extend it into other areas of a viewer's behavior.

Clean meat will require much less land and will cause far less climate change than conventional meat.

Further, another study2 mentioned in the impacts report recommended the criteria should be changed to require at least 10 more native tree species per hectare than the local baseline of highly disturbed areas, since even technified «sun» coffee farms had 35 tree species.

This is an incredibly difficult question to answer for a variety of reasons, most importantly because over the years our once vaunted «beautiful» style of play has become a shadow of it's former self, only to be replaced by a less than stellar «plug and play» mentality where players play out of position and adjustments / substitutions are rarely forthcoming before the 75th minute... if you look at our current players, very few would make sense in the traditional Wengerian system... at present, we don't have the personnel to move the ball quickly from deep - lying position, efficient one touch midfielders that can make the necessary through balls or the disciplined and pacey forwards to stretch defences into wide positions, without the aid of the backs coming up into the final 3rd, so that we can attack the defensive lanes in the same clinical fashion we did years ago... on this current squad, we have only 1 central defender on staf, Mustafi, who seems to have any prowess in the offensive zone or who can even pass two zones through so that we can advance play quickly out of our own end (I have seen some inklings that suggest Holding might have some offensive qualities but too early to tell)... unfortunately Mustafi has a tendency to get himself in trouble when he gets overly aggressive on the ball... from our backs out wide, we've seen pace from the likes of Bellerin and Gibbs and the spirited albeit offensively stunted play of Monreal, but none of these players possess the skill - set required in the offensive zone for the new Wenger scheme which requires deft touches, timely runs to the baseline and consistent crossing, especially when Giroud was playing and his ratio of scored goals per clear chances was relatively low (better last year though)... obviously I like Bellerin's future prospects, as you can't teach pace, but I do worry that he regressed last season, which was obvious to Wenger because there was no way he would have used Ox as the right side wing - back so often knowing that Barcelona could come calling in the off - season, if he thought otherwise... as for our midfielders, not a single one, minus the more confident Xhaka I watched played for the Swiss national team a couple years ago, who truly makes sense under the traditional Wenger model... Ramsey holds onto the ball too long, gives the ball away cheaply far too often and abandons his defensive responsibilities on a regular basis (doesn't score enough recently to justify): that being said, I've always thought he does possess a little something special, unfortunately he thinks so too... Xhaka is a little too slow to ever boss the midfield and he tends to telegraph his one true strength, his long ball play: although I must admit he did get a bit better during some points in the latter part of last season... it always made me wonder why whenever he played with Coq Wenger always seemed to play Francis in a more advanced role on the pitch... as for Coq, he is way too reckless at the wrong times and has exhibited little offensive prowess yet finds himself in and around the box far too often... let's face it Wenger was ready to throw him in the trash heap when injuries forced him to use Francis and then he had the nerve to act like this was all part of a bigger Wenger constructed plan... he like Ramsey, Xhaka and Elneny don't offer the skills necessary to satisfy the quick transitory nature of our old offensive scheme or the stout defensive mindset needed to protect the defensive zone so that our offensive players can remain aggressive in the final third... on the front end, we have Ozil, a player of immense skill but stunted by his physical demeanor that tends to offend, the fact that he's been played out of position far too many times since arriving and that the players in front of him, minus Sanchez, make little to no sense considering what he has to offer (especially Giroud); just think about the quick counter-attack offence in Real or the space and protection he receives in the German National team's midfield, where teams couldn't afford to focus too heavily on one individual... this player was a passing «specialist» long before he arrived in North London, so only an arrogant or ignorant individual would try to reinvent the wheel and / or not surround such a talent with the necessary components... in regards to Ox, Walcott and Welbeck, although they all possess serious talents I see them in large part as headless chickens who are on the injury table too much, lack the necessary first - touch and / or lack the finishing flair to warrant their inclusion in a regular starting eleven; I would say that, of the 3, Ox showed the most upside once we went to a back 3, but even he became a bit too consumed by his pending contract talks before the season ended and that concerned me a bit... if I had to choose one of those 3 players to stay on it would be Ox due to his potential as a plausible alternative to Bellerin in that wing - back position should we continue to use that formation... in Sanchez, we get one of the most committed skill players we've seen on this squad for some years but that could all change soon, if it hasn't already of course... strangely enough, even he doesn't make sense given the constructs of the original Wenger offensive model because he holds onto the ball too long and he will give the ball up a little too often in the offensive zone... a fact that is largely forgotten due to his infectious energy and the fact that the numbers he has achieved seem to justify the means... finally, and in many ways most crucially, Giroud, there is nothing about this team or the offensive system that Wenger has traditionally employed that would even suggest such a player would make sense as a starter... too slow, too inefficient and way too easily dispossessed... once again, I think he has some special skills and, at times, has showed some world - class qualities but he's lack of mobility is an albatross around the necks of our offence... so when you ask who would be our best starting 11, I don't have a clue because of the 5 or 6 players that truly deserve a place in this side, 1 just arrived, 3 aren't under contract beyond 2018 and the other was just sold to Juve... man, this is theraputic because following this team is like an addiction to heroin without the benefits

The board so far have been happy with Wenger keeping us in the champions league and a top 4 position in the premier league and as long as Arsenal continue to maintain that status then Wenger will remain as boss until he retires, the next manager will be required to do the exact same given that is what the board want as a minimum and so change will only come with a change of board.

If there really is any ambition then a far more enlightened and visionary approach to managing the club is required; one that naturally recognises the need to survive but also has an eye on a future that doesn't get reset with every change of manager.

Wholesale changes are not necessarily required, but a few tweaks to the starting lineup (plus a manager who can motivate them) would make this side far stronger than the 15/16 incarnation.

A second pilot session was then conducted with five different fathers 1 month later, with no further changes required.

After seven days, however, your baby should require far more changes in a 24 - hour period.

They also require fewer changes since they are far more absorbent than cloth diapers and an inner lining keeps wetness away from the skin and helps to prevent leaks.

He added further changes to the law would be introduced next year which would require the public sector to involve disabled people at every step of their policy - making processes.

By changing economic opportunities, requiring people to move away from home to find work and (allied to new technologies) making information and ideas available easily to people without their having to go anywhere, globalisation also facilitated the renewal of national and regional cultures and furthered the visibility and acceptance of, for example, diverse sexualities.

Amid delays that were based, in part, on political point - scoring, the system lasted only five years before the Welsh Assembly Government moved forward with a referendum to get rid of the LCO system and devolve further powers in one go — evidence, perhaps, that a system which requires the agreement of both devolved and central governments on policy changes might prove detrimental to effective governance.

A new treaty would be required for further enlargement, for example to include Turkey, while many believe some kind of document consolidating recent changes to the union is necessary.

And he dismissed suggestions that they were just another consultation exercise - most of the changes would require primary legislation, which was why further consultation was needed with a view to publishing a white paper in the autumn.

The delegates approved two resolutions: one calling for the proper use of assessments to further education, and the other calling for the state Board of Regents to hold public hearings on the implementation of the required changes to the teacher evaluation system.

A Cuomo administration official objected to the characterization that the new legislation would require further changes at SUNY.

«The eurozone is examining all sorts of further steps that need to be taken in terms of co-ordination, some of which I believe will require a treaty change.

The whole thing looks rather odd to me, as I would have expected that changes to the fundamental rules of the House to require far more than a simple majority.

But this is an essential, unavoidable part of the process: this kind of constitutional change requires extensive scrutiny so it can be improved as far as possible.

All the Bill requires is that the Government consults before imposing further changes.

Further to this item, I am told that some of the «party whips» have already rebelled without being required to resign: Stephen Gilbert on Monday on an amendment on boundary changes, Bob Smith on the London Local Authorities Bill.

He further stated that for such an incident to be avoided in future a change in attitude is required from the general public.

Published today in the journal Nature Geoscience, the paper concludes that limiting the increase in global average temperatures above pre-industrial levels to 1.5 °C, the goal of the Paris Agreement on Climate Change, is not yet geophysically impossible, but likely requires more ambitious emission reductions than those pledged so far.

Such decoupling, however, has not yet happened, and would require far - reaching change in policies and tax reforms at the global and national levels.

All that will require far more knowledge about how genetic modification changes a plant.

Professor Tim Jordan added: «Our present findings indicate considerable stability rather than developmental change in the use of letter position in word recognition, and further work is now required to see how this this fits in with the general process of reading.»

The case has long been considered a high - stakes test of how far the federal Endangered Species Act can require changes to modern society aimed at ensuring the continued viability of species considered iconic.