Sentences with phrase «change upon binding»

This has been used to create reporters for second messengers by using protein (domains) that undergo a conformational change upon binding of e.g. Ins (1,4,5,) P3, calcium or cAMP.

Not exact matches

With many like - minded people in the same room, you are bound to meet someone that will give a little golden nugget that may change everything for you or you may stumble upon a great strategic alliance or a future business partner.

If Jesus lays his hand upon someone they are bound to be changed.

What we will get, as law binding upon us and impossible to change democratically, is the moral truth of a majority of nine justices.

«In the case of glycoprotein hormone receptors, the family of proteins that includes the thyroid receptor, upon binding of the extracellular hormone, the intramolecular activator (p10) induces structural changes of the receptor protein, triggering activation of the intracellular signaling cascade.»

The researchers focused on glutamate - receptor and ligand - binding proteins that go through large conformational changes, like opening and closing, upon binding.

* Bugfixes - Super Armor effect: Fixed bug where characters» white glow disappeared for a moment before fading out once the effect ends - Fixed shuddering effect when killed while incapacitated by a spin - Brynhildr (Character Special Ability): Fixed cancel effect while doing a wheelie in Overdrive mode - Brynhildr (Special Move 2): Fixed bug where the cancel effect remained in place while keeping an opponent in the air with attacks - Odin (Ranged mode, Special Move 2): Fixed bug where the marker would appear out of bounds when using move near a border - Odin (Ravens): Fixed bug where Odin would stick to the ceiling upon hitting it and be unable to move up or down - Odin (Ranged Attack): Fixed bug where the hitboxes for the Ravens» shots were reversed if you changed lock - on targets immediately after launching Ranged Attack - Odin (Sweep mode, Special Move 2): Fixed bug where satellite - cannon shots would land on the ground even in areas with roofs.

They are meeting to try and agree to a global legally binding climate treaty to keep global warming below 2 degrees Celsius, which is the agreed upon target that scientists say the world can not exceed if we are to avoid catastrophic runaway climate change.

79 DOS 99 Matter of DOS v. Pagano - disclosure of agency relationships; failure to appear at hearing; proper business practices; unauthorized practice of law; unearned commissions; vicarious liability; fraudulent practice; jurisdiction; ex parte hearing may proceed upon proof of proper service; DOS has jurisdiction after expiration of respondents» licenses as acts of misconduct occurred and the proceedings were commenced while the respondents were licensed; licensee fails to timely provide seller client with agency disclosure form prior to entering into listing agreement and fails to timely provide agency disclosure form to buyer upon first substantive contact; broker fails to make it clear for which party he is acting; broker violates 19 NYCRR 175.24 by using exclusive right to sell listing agreement without mandatory definitions of «exclusive right to sell» and «exclusive agency»; broker breaches fiduciary duties to seller clients by misleading them as to buyer's ability to financially consummate the transaction; broker breaches his fiduciary duty to seller by referring seller to the attorney who represented the buyers when he knew or should have known such attorney could not properly protect seller's interests; improper for broker to use listing agreements providing for broker to retain one half of any deposit if forfeited by buyer as such forfeiture clause could, by its terms, allow broker to retain part of the deposit when broker did not earn a commission; broker must conduct business under name as it appears on license; broker engaged in the unauthorized practice of law in preparing contracts for purchase and sale of real estate which did not contain a clause making it subject to the approval of the parties» attorneys and were not a form recommended by a joint bar / real estate board committee; broker demonstrated untrustworthiness and incompetency in using sales contract which purported to change the terms of the listing agreement to include a higher commission; broker demonstrated untrustworthiness and incompetency in using contracts of sale which were unclear, ambiguous, vague and incomplete; broker failed to amend purchase agreement to reflect amendment to increase deposit amount; broker demonstrated untrustworthiness in back - dating purchase agreements; broker demonstrated untrustworthiness in participating in scheme to have seller hold undisclosed second mortgage and to mislead first mortgagee about the purchaser's financial ability to purchase; broker demonstrated untrustworthiness by claiming unearned commission and filing affidavit of entitlement for unearned commission; DOS fails to establish by substantial evidence that respondent acted as undisclosed dual agent; corporate broker bound by the knowledge acquired by and is responsible for acts committed by its licensees within the actual or apparent scope of their authority; corporate and individual brokers» licenses revoked, no action taken on application for renewal until proof of payment of sum of $ 2,000.00 plus interests for deposits unlawfully retained