Sentences with phrase «changes in a sequence of»

It persists, in large part, due to continual changes in the sequence of amino acid «building blocks» that make up the viral protein hemagglutinin, enabling it to avoid recognition and removal by immune system antibodies.

Cystic fibrosis, achondroplasia, phenylketonuria and Huntington's disease are each caused by simple changes in the sequence of a single gene.

The abnormality in ALK that arises in NSCLC is not, strictly speaking, a mutation (a change in the sequence of DNA within a gene).

«We detect changes in the sequence of code the program runs, ones often introduced by malicious programs.

Dr Farris notes: «This study examines the relationship between arc magmatism and tectonic change in a sequence of volcanic rocks along the Panama Canal.

Kazuko Nishikura, Ph.D., discovered a mechanism of RNA regulation through which cells can make discrete changes in the sequence of nucleotides — the «letters» in the RNA code, ultimately affecting the protein product.

Not exact matches

«But we can say with a fair bit of certainty that all that sequence of changes, starting several years ago, has succeeded in adding more buffering to the system.»

[1:20] How the kindness of a stranger changed Tony's life [3:35] Peter Diamandis talks about the origins of X Prize [6:30] Technology helping the agricultural industry [7:00] Sequencing genomes [8:55] Life - work integration [11:15] Finding your highest calling in life [12:00] Reframing what is «impossible» [14:00] Strategy vs. psychology [15:00] Changing your state [16:00] The science of achievement, the art of fulfillment [19:00] Living in a beautiful state [24:00] Thinking 10x bigger [28:00] Surrounding yourself with a «nothing is impossible» community [29:00] The news pollutes your mind [31:00] Tony's natural gifts and core beliefs [33:30] Overcoming failure and criticism [37:45] Defining your environment [40:00] Life happens for you, not to you [42:00] Rituals and practices to up your game [46:30] Tony's priming process

At DiscoverOrg, this might take the form of a data enrichment and matching exercise, a custom buildout to support changes in a go - to - market strategy, or something as simple as a workshop on how to overcome email deliverability issues or how to write email sequences for a drip campaign.

Overall, as the statements after the past five Board meetings have made clear, the sequence of changes to the cash rate, other adjustments by lenders in response to the rise in term funding costs since mid 2007 and tighter credit standards have combined to produce financial conditions that are tight.

Vestigial features, study of ebryonic development, biogeography, DNA sequencing, examining pseudogenes, study of endogenous retroviruses, labratory direct examination of natural selection in action in E-Coli bacteria, lactose intolerance in humans, the peppered moth's colour change in reaction to industrial pollution, radiotrophic fungi at Chernobyl all add to the modern evolutionary synthesis.

Several considerations of a more specific kind are relevant to the analysis of action sequences that result in religious change.

7 - If we defined growth as adding new material to our bodies, then DNA is living, because in the process of replication it add new sequences to its structure, but even in this case we have say it is non-living because DNA is not showing development which is the second part of growth, and simply development is the changes in structure living things undergo as it grow and age.

On this basis, Eigen maintains that abrupt changes of a quite major sort are to be expected in the normal course of events, as a quasi-species centered on one sequence is rapidly replaced by a rather different successor quasi-species centered quite far away on one of the extensions of the former species.

Sympathetic memory and anticipation, which are ingredient in every occasion of experience, are the forces that give a measure of identity through change to the present actual experience and past and future experiences in the same sequences.8

Tangible proof can be found by studying vestigial features, ebryonic development, biogeography, DNA sequencing, pseudogenes, endogenous retroviruses, labratory direct examination of natural selection in action in E-Coli bacteria, lactose intolerance in humans, the peppered moth's colour change in reaction to industrial pollution, radiotrophic fungi at Chernobyl... all of these things add to the modern evolutionary synthesis.

Chad, please inform us on exactly where, in the sequence of changes described in the article, God pointed his magic wand...

For example, we added in a sequence of colour changes for Milo and some sounds, much to the amusement of my children you can even record yourself talking, or making noises and add those to the code too.

«After presenting our findings to NYCHA in January 2015, NYCHA maintained that 4.6 million work order numbers could not be accounted for because of a «skip - sequencing» issue that was corrected as a result of unrelated Maximo system changes in March 2014,» Stringer's audit says.

Nwoga who is the Vice Chairman of APC in Enugu East senatorial zone is also asking the court to determine «Whether the National Assembly in exercise of her law making powers can make a law to change the sequence of elections, already adopted and published by INEC, pursuant to the powers conferred on it by the constitution.»

«Therefore, we are not in support of the change in the sequence because it can only cause unnecessary spending by the electoral body, despite the economic issues in the country.

This sequence is so widespread because it evolved in the common ancestor of all life, and as it carries out a crucial process, it has barely changed ever since.

Assessing the influence of individual DNA base changes is particularly difficult in noncoding regions, so they instead identified bigger alterations, so - called structural variants, in which large sequences of DNA are inverted, duplicated, or deleted.

In the new research, the UB scientists found they could reverse those social deficits with a very low dose of romidepsin, which, they found, restores gene expression and function using an epigenetic mechanism, where gene changes are caused by influences other than DNA sequences.

«These results change our understanding of when the largest living group of vertebrates evolved and allow us to iron out a lot of the wrinkles in our understanding of the sequence of evolutionary events.»

The Human Genome Project, which sequenced the 3 billion pairs of nucleotide bases in human DNA, was a piece of cake in comparison: Epigenetic markers and patterns are different in every tissue type in the human body and also change over time.

By contrast, in more than 90 % of endometrial cancers, the gene has undergone hypermethylation, an epigenetic modification that doesn't change its DNA sequence but renders it inactive.

«We have discovered that the two more destructive pathogens share a pattern of parallel changes in their core metabolic pathways that enables them to exploit more efficiently the nutrient resources available in banana,» said Stergiopoulos, who along with bioinformatician Ti - Cheng Chang, led the effort to sequence and analyze the fungal genomes of eumusae leaf spot and yellow sigatoka, comparing their findings with the previously sequenced black sigatoka genome sequence.

Hothead mutants contained changes in other parts of their DNA, too, all of which matched the sequences of the plants» grandparents or great - grandparents but not their parents.

The team also looked at changes in the genetic sequence of the Zika NS1 protein over time, noted David L. Akey, a research scientist in Smith's lab and the study's other lead author.

The new analysis, based on data assembled primarily by graduate student Yan - Jie Feng at Sun Yat - Sen University in Guangzhou, China, focused on the sequences of 95 genes located on chromosomes in the nucleus and how they changed over time.

But Aniket Gore of the US's National Institute of Child Health and Human Development and colleagues haven't found any disabling changes in the DNA sequences of eye development genes in the cavefish.

The authors analyzed changes in the viral sequence and conclude that the current outbreak probably resulted from the spread of the virus from central Africa in the past decade.

Researchers at Umeå University show in a new, detailed structural study, published in the journal Nature Communications, how the binding of the signal - sequence triggers a number of structural changes within the SRP particle.

All that changed this month, with the publication of a 400,000 - year - old mitochondrial genome sequenced from the remains of an early human found in a cave in Spain.

Among them is the sequence of time intervals on a stock exchange when there is a change in share prices, which does not happen uniformly.

They have since collected chloroplast sequence data from six different plant species that spread their seeds in a variety of ways, and will use CallHap to investigate how their seed dispersal methods might perform in response to climate change.

Individualized actions were taken in 23 of the 91 (25 percent) based on clinical sequencing findings, including change in treatment for 14 patients (15 percent) and genetic counseling for 9 patients (10 percent).

In the case of β - ionone, the smell associated with violets, McRae and colleagues managed to pinpoint the exact mutation (a change in the DNA sequence) in the odorant receptor gene OR5A1 that underlies the sensitivity to smell the compound and to perceive it as a floral note — people who are less good at smelling β - ionone also describe the smell differently, as sour or pungent, and are less likely to find it pleasanIn the case of β - ionone, the smell associated with violets, McRae and colleagues managed to pinpoint the exact mutation (a change in the DNA sequence) in the odorant receptor gene OR5A1 that underlies the sensitivity to smell the compound and to perceive it as a floral note — people who are less good at smelling β - ionone also describe the smell differently, as sour or pungent, and are less likely to find it pleasanin the DNA sequence) in the odorant receptor gene OR5A1 that underlies the sensitivity to smell the compound and to perceive it as a floral note — people who are less good at smelling β - ionone also describe the smell differently, as sour or pungent, and are less likely to find it pleasanin the odorant receptor gene OR5A1 that underlies the sensitivity to smell the compound and to perceive it as a floral note — people who are less good at smelling β - ionone also describe the smell differently, as sour or pungent, and are less likely to find it pleasant.

In a study that included children and young adults with relapsed or refractory cancer, incorporation of integrative clinical genomic sequencing data into clinical management was feasible, revealed potentially actionable findings in nearly half of the patients, and was associated with change in treatment and family genetics counseling for a small proportion of patients, according to a study in the September 1 issue of JAMIn a study that included children and young adults with relapsed or refractory cancer, incorporation of integrative clinical genomic sequencing data into clinical management was feasible, revealed potentially actionable findings in nearly half of the patients, and was associated with change in treatment and family genetics counseling for a small proportion of patients, according to a study in the September 1 issue of JAMin nearly half of the patients, and was associated with change in treatment and family genetics counseling for a small proportion of patients, according to a study in the September 1 issue of JAMin treatment and family genetics counseling for a small proportion of patients, according to a study in the September 1 issue of JAMin the September 1 issue of JAMA.

Their trouble with language had been caused by the change of a single nucleotide of DNA — just one letter in the genetic sequence.

Thus in the early generations, most of the machines bumbled about randomly, but gradually, as «mutations» made changes in the robots» behavior, some of them stumbled onto productive sequences of behaviors.

The researchers analyzed the samples using immunohistochemistry and RNA sequencing to study the changes in the tumor immune microenvironment of patients who received and did not receive chemotherapy, and changes before and after chemotherapy.

Situated along the proposed southern dispersal route, the Al Sibetah alluvial fan sequence provides a unique and sensitive record of landscape change in southeast Arabia.

«The Neandertal genome sequence just by itself will not tell us what makes humans special, it will always be in conjunction with other work that really addresses the biology of a specific change,» he says.

In inherited diseases, some part of this process has gone awry due to a mutation, or change in the DNA sequencIn inherited diseases, some part of this process has gone awry due to a mutation, or change in the DNA sequencin the DNA sequence.

You would expect to see it in the regulatory sequences because then the effect of a small change can be huge because you are affecting the timing and maybe the sequence of events in development.

Many are probably simply the consequence of 6 million years of genetic drift, with little effect on body or behavior, whereas other small changes — perhaps in regulatory, noncoding sequences — may have dramatic consequences.

In work published last year, the team sequenced selected DNA regions of 38 cactus species and concluded that modern Pereskia actually represents two evolutionary groups, one of which probably split off from the rest of the cacti before they had undergone their dramatic anatomical changes.

More than two decades ago, in one of the first papers using gene sequences to find signatures of natural selection, scientists hypothesized that a molecular change in an enzyme gave the Drosophila melanogaster fruit fly species its superior ability to metabolize alcohol.