Consequently, despite the extensive and highly successful efforts of many researchers to develop infection models in Drosophila, the outcomes of infection are often measured by end - points such as insect death (survival of a cohort of insects over time) or
changes in cell morphology at fixed periods throughout infection (often monitored by staining different elements of the cytoskeleton).
During the culture of these cells, we noticed
a change in cell morphology from the cobble stone - like shape typical of epithelial cells to a more spindle - like and scattered appearance (Figure 2A, lower panel), indicating these cells may be undergoing EMT.
Not exact matches
Indeed, pre-treating of human
cells with a compound that inhibits
changes in mitochondrial
morphology allows protecting the host
cell from Legionella - induced
changes of mitochondria and restricts bacterial infection of human
cells.
Our findings demonstrate that induction of IAPP misfolding and aggregation by administration of preformed IAPP - aggregated seeds leads to the development of marked T2D - like pathology, including severe hyperglycemia, impaired glucose homeostasis, loss of β
cells, and
changes in islets
morphology.
He is currently funded (2016 - 2021) by the National Cancer Institute to study radiation induced
changes in neuron
cell dendritic
morphology in cancer treatment with X-rays, protons and carbon beams, and has received grants from the Department of Energy and NASA
in the past.
Mitotic position and
morphology of committed precursor
cells in the zebrafish retina adapt to architectural
changes upon tissue maturation.
These
cells could be expanded for at least 20 passages (2 ∧ 20 or at least a million-fold expansion) and differentiated into endothelial
cells without any significant
change in their
morphology (Figure S4).
(2010) Dendritic
Morphology Changes Prior to Uptake and Transport Dysfunction
in Retinal Ganglion
Cells of the DBA / 2J Mouse Model of Glaucoma (Investigative Ophthalmology & Visual Science, 51: ARVO E-Abstract 2141).
Following CNS damage, microglia
change from a surveillant to a reactive state, displaying alterations
in cell morphology and phenotypes that vary based upon the type and extent of (insulting) stimulus to which they are exposed and respond.