«Our research demonstrated and supports earlier research from elsewhere that
changes in cells occur before you can see them.
Not exact matches
Extracts from this garlic even protected
cells in a laboratory dish from certain types of damage.13 This isn't really surprising when you consider the nutritional
changes that typically
occur in plants when they sprout.
The
change in load
cell output
occurring with time, while under load, and with all environmental conditions and other variables remaining constant; usually measured with Rated Load applied and expressed as a percent of Rated Output over a specific period of time.
It
occurs when some of the red blood
cells change into a «sickle» shape and cause a buildup of red blood
cells in small blood vessels.
The acceleration of the healing process
occurs due to
changes in the microenvironment
in the wound, which
change the behaviour of specific immune
cells.
«A surprise was how many major
changes occurred to genes
in the blood
cells,» Yang said.
So if you take evolution
in its broad sense to mean genetic
changes across the population, then it might be
occurring even without
cell division, says Briggs.
Plath's team found that the
changes that happen
in cells during reprogramming
occur in a sequential stage - by - stage manner, and that importantly, the stages were the same across all the different reprogramming systems and different
cell types analyzed.
«Next, we asked
in which
cells are genetic
changes occurring.»
The new device uses light scattering spectroscopy (LSS) to detect the structural
changes that
occur in cancerous or pre-cancerous
cells by bouncing light off tissues and analyzing the reflected spectrum.
So instead of going through a phase
change from liquid to solid, glass formation
occurs, which allows
cells to be preserved
in their existing state without going through the complete dehydration that you achieve
in slow cooling.
The study involved extracting Ribonucleic acid or RNA — found
in the
cells of all living organisms — to develop a transcriptome — the gene readouts
in a
cell — to examine what
occurs during the different developmental stages of the cockroach pregnancy and to explore if those
changes hold wider applications for other mammals.
By March 2014 — about the time the epidemic was detected, but some 3 months after the first case actually
occurred — the sequences had split into two distinct lineages, one of which was characterized by a single amino acid
change in a region of the virus's surface protein and allows it to bind to
cells.
Scientists have hypothesized that magnetite, a form of iron that's the most magnetic of naturally
occurring minerals, is the key ingredient
in specialized
cells that react to
changes in magnetism.
However, when chronic inflammation
occurs in a blood vessel — typically
in response to diabetes, high cholesterol and cigarette smoking — the smooth muscle
cells in the walls of arteries
change their behavior.
Furthermore, the normal ductal
cells that are able to develop into pancreatic cancer represent about 10 percent of the
cells in the pancreas, complicating efforts to pinpoint the
changes that
occur as the tumor develops.
Lin observed that this
change in nucleus shape is similar to what
occurs during
cell division and hypothesized that there may be similar underlying mechanisms behind
cell division and regeneration.
The study, published
in Nature Communications, examined the
changes that
occur in cancer
cells as they break away from tumours
in cell cultures, zebrafish and mice.
Metabolic
changes in cells can
occur at the earliest stages of disease.
The Tübingen group was making organotypic eye cultures and examining
in vitro the
changes that
occur in the
cells of living individuals.
In dendrites and axons these rapid structural and functional
changes occur concurrently — their length, size, shape, and number
change to suit the needs of neuronal
cell body communication.
This approach has revealed new insights into the timing and coordination of the
changes in gene activity and modifications to the DNA that
occur as
cells are reprogrammed from one state to another.
Similarly, other epigenetic
changes occur in how DNA and proteins are compacted
in the nucleus of the
cell.
It may, for example, partly account for the differences
in brain structure and behavior between identical twins, and could even affect thought processes by subtly influencing the
changes in nerve
cell connections that
occur with experience.
Assistant Professor Camila dos Santos of Cold Spring Harbor Laboratory (CSHL) is studying stem
cells in the breast for clues about what
changes occur when normal breast
cells become cancerous.
Furthermore, they integrated single -
cell datasets of pancreatic tissue from humans and mice, thereby identifying 10
cell types that were shared across species and defining the evolutionary
changes occurring in each group.
The study has important implications for human health, and is particularly useful for understanding the
changes that
occur in cells during the development of the tumors that underlie cancers.
If the drugs
in question decay so quickly, this would surely not
change, given that the red blood
cells are surrounded by blood, where decomposition would still
occur.
«We wanted to understand how a long - term high - fat diet influences the biology of stem
cells, and how such diet - induced
changes that
occur in stem
cells impact tumor initiation
in the intestine,» Yilmaz says.
The NIH Common Fund's Library of Integrated Network - based Cellular Signatures (LINCS) program aims to create a network - based understanding of biology by cataloging
changes in gene expression and other cellular processes that
occur when
cells are exposed to a variety of perturbing agents.
Forced expression of this SMN1 variant
in cultured non-neuronal
cells induces the formation of neurite - like extensions, a
change in cell shape reminiscent of that
occurring when motor neurons send out axons to their muscle targets.
This collaboration led to the discovery of distinct behavioral
changes that
occur in the motions of individual proteins on the surface of
cells, thereby helping elucidate what it means for the pathway to be active or inactive.
The morphological
changes manifested
in the
cell types linked to larger toepads exemplify
cell type differentiation that must be controlled by the physiology of reproduction and properly timed nutrient - dependent reproductive sexual behavior, which probably
occurs near the location of the higher perches.
Chinnaiyan's lab, which has extensively analyzed how genes and proteins
in prostate cancer
cells reflect these
changes, thought that profiling
cells» metabolites would offer an even more «holistic picture of the molecular alterations that
occur,» he said.
Some of these will light up when certain
changes occur in a
cell.
A. Melanoma is a cancer of pigment
cells and all melanomas share some characteristics but they also differ: the genetic
changes which define cancers
occur in the cancer
cells at random and cancers are all therefore a little different.
Some studies have identified a number of regions of methylated DNA (one key way
in which epigenetic
changes occur) that are different
in fat
cells of mice fed high - fat diets than
in cells of mice with normal diets.
His discoveries include insights into how
changes in gene expression affect T
cell exhaustion, a waning of immune function that
occurs in response to chronic viral infection and cancer.
He said stem -
cell treatments on Parkinson's patients could
occur as early as 2008, even without a
change in Bush's policy.
The most important
changes occur in T
cell immunity, manifested sometimes dramatically as altered clonal expansions of
cells of limited antigen specificity and a marked shrinkage of the T
cell antigen receptor repertoire.
As
cells divide and differentiate,
changes in transcriptional profile
occur, leading to considerable phenotypical diversities forming different subpopulation of
cells and tissues
in living organisms.
The afternoon of the second day focused on somatic
changes in melanoma, that is
changes that
occur in the tumour itself, and this session saw talks from ESR07 Sofia Chen on the mutational landscape of primary melanoma tumours; ESR08 Catarina Salgado on DNA hydroxymethylation (a form of regulation)
in melanoma and naevi; and ESR10 Adriana Sanna on epigenetic regulation (reversible
changes to the DNA which can turn genes on / off) of melanoma
cell phenotypes.
The
changes to
cell reprogramming that the scientists observed
in the young flies can
occur inappropriately
in adult human
cells — spurring cancer, for example.
A very specific and important event
occurs after 5 — 6 days: the blastocyst
changes very subtly and the
cells in the inner
cell mass lose the ability to read all of their DNA.
Finally, there is evidence that the DNA
in our
cells is protected by naturally
occurring substances
in Brussels sprouts, and since many environmental toxins can trigger unwanted
change in our DNA, Brussels sprouts can help prevent these toxin - triggered DNA
changes.
(6)(12) Since genetic
changes occur within
cells only after the breakdown of efficient metabolism, (7)(8)(9)(10)(11) it is unlikely that genetics play any kind of significant role
in headache occurrance, but the environmental theory is likely.
Aging
occurs as a result of
changes in the mitochondria, which produce less and less energy for the body's
cells over time.
Thyroid cancer
occurs when
cells in your thyroid undergo genetic
changes (mutations).
Other cellular and molecular biological
changes occur in muscle, including the addition of more sarcomeres (structural units of a muscle
cell) to muscle (De Deyne 2001).
This lag
in energy production tends to
occur earlier than
changes in blood
cell production, so the muscle fatigue and
changes in concentration are likely to be noticeable long before laboratory testing shows low blood
cell production.