Scientists investigating the mechanisms of Down Syndrome (DS) have revealed the earliest developmental
changes in embryonic stem cells caused by an extra copy of human chromosome 21 — the aberrant inheritance of which results in the condition.
Not exact matches
Using a mathematical model known as the Ising model, invented to describe phase transitions
in statistical physics, such as how a substance
changes from liquid to gas, the Johns Hopkins researchers calculated the probability distribution of methylation along the genome
in several different human
cell types, including normal and cancerous colon, lung and liver
cells, as well as brain, skin, blood and
embryonic stem cells.
The creation of the Centre of Regenerative Medicine
in Barcelona (CMRB) reflects «a
change in the Spanish public policy regarding derivation and use of human
embryonic stem cells (HESC), based on a progressive evolution of the public awareness and sensibility of the Spanish [citizenry],» says CMRB Director Juan Carlos Izpisúa Belmonte
in an e-mail.
Contributions from careful, sober - minded scientists can also help defuse controversy
in fields that get headlines, such as climate
change and
embryonic stem cells.
Changes in cellular metabolites have been shown to regulate
embryonic stem cell development at the earliest stages of life.
«
Changes in metabolites can regulate earliest stages of development: Findings may offer insights into a variety of disorders, advance
embryonic stem cell research.»
So researchers began testing genes that were only active
in embryonic stem cells to try to pin down those capable of triggering the
change.
Thorough study of
changes in the gene activity regulation mechanism showed that reprogrammed and
embryonic stem cells are similar.
But
embryonic clones, the source of an endless supply of
stem cells imprinted with one's personal DNA, could alter the equation
in favor of the patient and augur a paradigm shift
in medicine on par with the
changes brought about by antibiotics and vaccines.
In Missouri, voters approved an initiative that
changes the state's constitution to protect
embryonic stem -
cell research.
2007 also saw one of the most game -
changing developments
in the
stem cell field; researchers learned how to create
cells like
embryonic stem cells, but instead of coming from an embryo these
cells are created from adult
cells, potentially
cells from any tissue
in the human body.
Obtaining patents
in Europe remains a challenge
in view of the European Patent Office's
changing laws and guidelines with respect to inventions directed to
embryonic stem cells.
To determine whether huntingtin is involved
in trafficking a specific subset of proteins, we measured
changes in global transcription levels
in embryonic stem cells and neurons lacking huntingtin.
Human
embryonic stem cells grown at the University of Wisconsin - Madison randomly
changed into
cell types found
in the A) gut B) brain C) bone marrow D) cartilage E) muscle F) kidney Scientists haven't learned to control the development.
* The role of the US
in global efforts to address pollutants that are broadly dispersed across national borders, such as greenhouse gasses, persistent organic pollutants, ozone, etc...; * How they view a president's ability to influence national science policy
in a way that will persist beyond their term (s), as would be necessary for example to address global climate
change or enhancement of science education nationwide; * Their perspective on the relative roles that scientific knowledge, ethics, economics, and faith should play
in resolving debates over
embryonic stem cell research, evolution education, human population growth, etc... * What specific steps they would take to prevent the introduction of political or economic bias
in the dissemination and use of scientific knowledge; * (and many more...)