Sentences with phrase «changes in the brain cells»

Dr. Lobo said that this latest research could help researchers better understand changes in brain cells and mitochondria from other addictive disorders.
This biochemical modification is essential in producing the changes in brain cell connectivity associated with learning, the study finds.
This way scientists can measure changes in the brain cells more accurately, she says.

Not exact matches

When behavior is successful our cells become finely tuned to what the animal was learning at the time while a failure shows little change in the brain or improvement in the monkey's behavior.
She demonstrated that early experience leads to lasting changes in the molecular structure of the brain and discovered a gene involved in the spread of brain cancer cells into healthy brain tissue.
Using a mathematical model known as the Ising model, invented to describe phase transitions in statistical physics, such as how a substance changes from liquid to gas, the Johns Hopkins researchers calculated the probability distribution of methylation along the genome in several different human cell types, including normal and cancerous colon, lung and liver cells, as well as brain, skin, blood and embryonic stem cells.
Using human fetal «mini-brains» grown in 3 - D cultures, scientists determined that a specific protein produced by the Zika virus changes the properties of neural stem cells in the developing brain of an infected fetus, potentially causing microcephaly in newborns (Ki - Jun Yoon, abstract 103.06, see attached summary).
Prestin changes shape when exposed to high - frequency sound, and this in turn deforms the fine hair cells, setting off an electrical impulse to the brain.
It has been particularly difficult to measure changes in electrical functions of cells grown within Organ Chips that are normally electrically active, such as neuronal cells in the brain or beating heart cells, both during their differentiation and in response to drugs.
Now, researchers have discovered that the drug changes the firing patterns of cells in a pea - size structure hidden away in the center of the brain.
Stories on a possible cause for severe morning sickness and how a mother mouse's care for her pups might trigger changes to the genomes in their brain cells
«Disturbances to these processes may cause neuronal stem cells to develop into different types of cells or may cause neurons to migrate to different locations in the brain, changing neuronal circuitry and potentially leading to behavioral disorders like schizophrenia.»
We thought that if viruses could bind to receptors in these spaces and change how brain cells normally communicate, the virus could change behavior of the infected animal.»
Researchers also studied the brain tissue of the infected mice under a microscope and found that the memory problems tracked with changes in nerve cells.
Holdcroft believes that the changes in the brain are more likely to be the result of changes in the volume of individual cells, rather than changes in the number of cells in the brain.
«The brain along with the reproductive system and every other cell in your body is exquisitely sensitive to exceedingly small changes in estrogen and other sex hormones, and the fact that the environment is full of chemicals that can activate estrogen receptors means this phenomenally sensitive system is being perturbed constantly by environmental factors.»
Even short - term blockages of this kind can lead to remarkable changes in the auditory system, altering the behavior and structure of nerve cells that relay information from the ear to the brain, according to a new University at Buffalo study.
Seven patients went on to require neurosurgery, which allowed the scientists to investigate in detail changes in the brain brought on by CAR T cell treatment.
The findings, published Sept. 20 in the Journal of Virology published by the American Society for Microbiology, were publicly revealed almost simultaneously with those from China - based scientists who found a change of a single amino acid made the virus more dangerous to developing brain cells.
Certain changes in synapses — the junctions between nerve cells in the brain — have been linked with brain disorders.
When the scientists recently gave mice a single dose of cocaine and looked for signs of autophagy in their brain cells, they detected autophagy - associated proteins and changes in vacuoles in adults and in mouse pups whose mothers had received cocaine while pregnant.
In new research, published in an article in The Journal of Neuroscience, Burger and Oline — along with Dr. Go Ashida of the University of Oldenburg in Germany — have investigated auditory brain cell membrane selectivity and observed that the neurons «tuned» to receive high - frequency sound preferentially select faster input than their low - frequency - processing counterparts — and that this preference is tolerant of changes to the inputs being receiveIn new research, published in an article in The Journal of Neuroscience, Burger and Oline — along with Dr. Go Ashida of the University of Oldenburg in Germany — have investigated auditory brain cell membrane selectivity and observed that the neurons «tuned» to receive high - frequency sound preferentially select faster input than their low - frequency - processing counterparts — and that this preference is tolerant of changes to the inputs being receivein an article in The Journal of Neuroscience, Burger and Oline — along with Dr. Go Ashida of the University of Oldenburg in Germany — have investigated auditory brain cell membrane selectivity and observed that the neurons «tuned» to receive high - frequency sound preferentially select faster input than their low - frequency - processing counterparts — and that this preference is tolerant of changes to the inputs being receivein The Journal of Neuroscience, Burger and Oline — along with Dr. Go Ashida of the University of Oldenburg in Germany — have investigated auditory brain cell membrane selectivity and observed that the neurons «tuned» to receive high - frequency sound preferentially select faster input than their low - frequency - processing counterparts — and that this preference is tolerant of changes to the inputs being receivein Germany — have investigated auditory brain cell membrane selectivity and observed that the neurons «tuned» to receive high - frequency sound preferentially select faster input than their low - frequency - processing counterparts — and that this preference is tolerant of changes to the inputs being received.
Prior research with cultured tissue had shown that a mix of chemicals could change bone marrow stem cells from mice to those resembling brain cells, but when a team led by neurologist Lorraine Iacovitti of Thomas Jefferson University in Philadelphia tried the same brew on human cells, the number altered was modest.
New research led by UC San Francisco scientists has revealed that mutations in a gene linked with brain development may dispose people to multiple forms of psychiatric disease by changing the way brain cells communicate.
The researchers traced these changes to a decrease in brain cells that release the hormone oxytocin in the hypothalamus, an area of the brain associated with food intake.
«By combining in vivo multiphoton microscopy and in vivo electrophysiology, our lab is better able to visualize how cells move and change over time in the living brain and explain how changes in these glial cells alter the visually evoked neural network activity,» says Kozai.
The team used this change in the variability of the song to look at how the activity of single cells in different parts of the brain altered their activity depending on the social environment.
She hopes to pinpoint which genes are expressed in each cell type when brain cells make long distance connections, and to make similar maps in other primates to chart what changed as brains rewired over the course of evolution.
Fifty - three of the brain cells showed significant changes in activity as the coils rotated, reacting to field strength and polarity.
Detlev Arendt and Joachim Wittbrodt, developmental biologists at the European Molecular Biology Laboratory in Heidelberg, Germany, jumped into the fray after Arendt noticed some vertebrate - like photoreceptor cells in the brains of ragworms, a marine species that hasn't changed much for 500 million years.
The work, which appears in the journal Cell, focuses on the regulation of «neuronal plasticity» — changes in neuronal structure — and its function in the brain.
The size of the brain's ventricles — cerebrospinal fluid - filled spaces deep within the brain — became progressively larger during the course of treatment, and changes were also seen within the subventricular zone, one of two structures in which new brain cells are generated in adults.
The team found significant changes in gene expression after light exposure in all cell types in the visual cortex — both neurons and, unexpectedly, nonneuronal cells such as astrocytes, macrophages and muscle cells that line blood vessels in the brain.
A new in vitro model Scientists developed a new research tool for this study that enabled them to monitor the spread of Tau aggregates whilst changing the synaptic connections between brain cells.
«Nature, meet nurture: Single - cell analysis reveals diverse landscape of genetic changes in the brain after a sensory experience.»
Looking for immune abnormalities throughout the lifespan of the mice, the group found that most immune system components stayed the same in number, but a type of brain - resident immune cells called microglia that are known first responders to infection begin to divide and change early in the disease.
The major advancement with the new study is that it demonstrates for the first time that self - repair in the adult brain involves astrocytes entering a process by which they change their identity to nerve cells.
To investigate just how this change affects an animal's sense of novelty, Burwell and her colleagues infected brain cells in rats» perirhinal cortex with a virus containing a light - activated channel.
Whereas place cells in a rat brain may change their firing rates if their environment is altered even a little — for example by changing the colour of the walls — those of grid cells remain robustly unchanged.
The faulty gene leads to cell death in neurons in the brain resulting in gradual physical, mental and emotional changes, and ultimately death.
In addressing the first question, the study showed that the brain's immune cells, microglia, which are known to become activated by LPS exposure as well as in most brain injuries and diseases, begin spewing out pro-inflammatory factors that change astrocytes» behavioIn addressing the first question, the study showed that the brain's immune cells, microglia, which are known to become activated by LPS exposure as well as in most brain injuries and diseases, begin spewing out pro-inflammatory factors that change astrocytes» behavioin most brain injuries and diseases, begin spewing out pro-inflammatory factors that change astrocytes» behavior.
The researchers concluded that in the early stages after stroke, improvements in voluntary movement can be attributed to a reduction in brain swelling because of the trauma and other spontaneous repairs, while later improvements result from «neuronal plasticity» — the reorganization or regeneration of nerve cells within the spinal cord in response to changes in the nerve network.
But a new study suggests that in the days and weeks that lead up to a brain forming in an embryo or fetus, altering the electrical properties of these cells can dramatically change how the ensuing brain develops.
Now researchers reporting in the Cell Press journal Neuron on July 18 show in a study conducted in rats that even a single exposure to nicotine temporarily changes how the brain's reward system responds to alcohol and increases the reinforcing properties of alcohol via stress hormones.
The past few decades, she adds, have revealed that brain cells are versatile, or plastic, changing their roles in response to new experiences.
The new study combined two methods: So - called «patch recording» of tiny voltages in single frog brain cells and how the voltages change in response to sounds of different lengths, and the administration of drugs that block neurotransmitters — a way to learn how brain cells respond to sound with and without the normal neurotransmitters.
After measuring millivolt changes in 58 brain cells in frogs in response to sound, the researchers used a mathematical model to convert the information into how much a brain cell was excited or inhibited by a given sound pulse.
«After a year of sound deprivation, we observed dramatic changes in the inner ear — notably, a significant loss of the synaptic connections through which the sensory cells send their electrical signals to the brain,» Dr. Maison said.
Researchers at the Neuronano Research Centre (NRC) at Lund University in Sweden have now shown that microglia, the brain's cleansing cells, and the enzymes that the cells use in the cleaning process, change in the presence of gelatin.
Changes in DNA methylation in brain cells has been an extremely active research area since these epigenetic changes were shown to alter the expression of genes needed to form and maintain long - term meChanges in DNA methylation in brain cells has been an extremely active research area since these epigenetic changes were shown to alter the expression of genes needed to form and maintain long - term mechanges were shown to alter the expression of genes needed to form and maintain long - term memories.
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