Sentences with phrase «changes in the functioning of»

Boulanger was senior author on a 2013 paper in the journal Learning and Memory that found that mice bred to produce less functional MHCI proteins exhibited striking changes in the function of the hippocampus, a part of the brain where some memories are formed, and had severe memory impairments.

Stress can cause changes in the function of the immune system, including reducing the number of natural killer cells that are known to battle cancer.

Astrocytes could thus play a key role in the early stages of the disease and changes in the function of these cells could lead to neurodegeneration.

«This allows us to identify subtle changes in the functioning of neuronal circuits that we never had access to before.»

Any change in the functioning of this gland can have varied effects on your pet's health.

There are other factors (changes in the natural sources of emissions in a warmed environment, changes in the function of traditional carbon sinks in a warmed environment, tipping points like increase forest fire activity in a warmed environment, etc.) that also play a significant role in the truly important number, which is accumulation of CO2 / e in the atmosphere and ocean acidification.

Their discovery was not accompanied by any attempt to demonstrate that the changes in gene architecture they found also involved a change in the function of the genes or were associated with different effects on bear physiology.

A change in functioning of one family member is automatically followed by compensatory changes in other family members.

Not exact matches

«A cascade of changing business conditions, changing organizational structures, and changing leadership has been forcing human resource departments to alter their perspectives on their role and function almost overnight,» wrote John Johnston in Business Quarterly.

At its core of this first hackable product will be a durable aluminum profile, made of 40 percent recycled material, which creates a flexible base to build seating or bedding «where comfort and functions can be altered to meet the changing needs in a home,» IKEA said last year.

We realised that there needs to be a major change in the way the system, the work culture and the mindsets of people function and above all it is of utmost importance for women professionals to believe that they can reach the top leadership positions.

The CEO's involvement in various functions and parts of the company will need to change materially as the years go by — or the CEO will need to be changed.

«When people are functioning at a high level in business and in the professions, they have jumped through so many hoops to get where they are that if there's a change along those lines, that all by itself can be something of concern,» says Dr. Boyd.

Slower growth — a function of structural changes such as an aging society — means economic slack created in the last recession is being eroded at a sluggish pace.

The advance is based on a technique that allows scientists to narrow in on a specific gene and cut - and - paste bits of DNA to change its function, known as CRISPR - Cas9.

«Today, the answers to those questions are different - you do not get much which does not come close to justifying the step function increase in the cost to upgrade, and as the below chart show the cost to upgrade changed dramatically with the introduction of the iPhone X.

Instead of leveraging the MBA to make one or even two career changes — such as securing a promotion or moving from a small financial services firm to Morgan Stanley (MS)-- triple jumpers shake up three variables all at once: country, job function, and industry — and they do all of this in a highly compressed timeframe.

Other changes have been in the works for months, including the departure soon of Glenn Butt, executive vice-president of automotive whose functions overseeing the auto department had been taken over by the company's head of marketing.

Secondly, just on the backlog conversion guidance, the lower spec — is the lower spec mix a function of the market or a change in your strategy?

Very different than my double edge razors, probably closest in function to my TTO, where the head and handle of the razor remain attached in order to change the blade (the handle does twist off if needed), however it seems as though changing this blade would be a bit more cumbersome than with a TTO.

By conducting policy in a transparent way and communicating what is important in determining the central bank's reaction function, I think policymakers can strike the best balance between a monetary policy that fully incorporates the complexity of the world as it is, while, at the same time, retaining considerable clarity about how the FOMC is likely to respond to changing circumstances.

Most recently, Mark pioneered the design of the Employee Experience at Airbnb, which was recognized as the # 1 Place to Work in 2016 by Glassdoor, and which has since inspired significant changes in the way organizations around the world are looking to expand the HR function to focus on the entire employee journey.

Previously, Phil was Chief Financial Officer, Manulife Asia, leading transformational change within the finance function in Asia and providing strong financial leadership to business decisions by influencing divisional strategy and business unit profitability, as well as leading financial due diligence of all merger and acquisition opportunities.

The speech lists five key fundamentals that should stand Australia in good stead: a strong institutional framework (including the rule of law, respect for property rights, a well - functioning public administration, and a well - established regulatory system); our people, who are diverse, well educated, have a «can do» mentality and a demonstrated capability for adjusting to change; a large endowment of mineral resources; large tracts of agricultural land and an ability to produce high - quality clean food; and an established services industry with the potential for considerable expansion as average incomes in Asia rise.

As long China pegs its currency, it's net capital account outflow is unlikely to change, because changes in reserves are simply a function of the net flows arising from the combination of the current account and the non-PBoC part of the capital account.

Second is the question of how markets will behave under stress - that is, whether they will be able to function in an orderly fashion in response shocks or broad changes in market sentiment.

However, over the last several months market volatility has returned with a vengeance — a function of changing monetary policy in the U.S. and a plethora of geopolitical risks popping up around the globe.

When the Canadian labour market is functioning normally, there are large flows of hires into employment and not - quite - so large flows of separations out of employment: the relatively small difference between the two is the change in total employment.

The chart below presents slope estimates, showing the 6 - month change in the S&P 500 as a function of the 6 - month change in the monetary base, at various leads and lags.

This change is likely a function of investor liquidations in Q4 2016, as markets anticipated a Fed rate hike, which has since reversed but at a subdued pace.

For the transformation to occur, it has to be driven by leaders across the organization, and we have seen the pace of this change begin to accelerate in every function.

This makes China's economic reaction function somewhat difficult for market participants to anticipate, because reactions on changing economic conditions may come in the form of fiscal or monetary policy, or a combination of both (the «dual bazooka» approach).

No, he went further and argued that the traditional separation of functions in the Canadian financial system were coming apart with or without government policy changes.

Public Power Corporation chief executive Manolis Panagiotakis referred on Thursday to the prospect of a considerable reduction in the utility's operating costs as well as extensive changes in its organization and function after the completion of its new business plan currently being drafted by consultant McKinsey & Company.

You can argue that the original organism had better eyesight than others of his species and therefore the change increased his ability to survive, but you ignore that the change had to occur in the first place, and if there was a change in the first animal the interconnectedness of the related bodily functions makes it impossible for the chance change — which by the way required the loss of genetic material — to have happened regardless of the amount of time you had.

For the philosophy of organism, changes are a function of the relation of actual entities in an event with respect to the extensive continuum.

One main function of NAFTA was to facilitate this change in Mexican agriculture.

Some of these pioneers in changing the church find that the best way to function as the Body of Christ is to leave the institutional church behind, and live and love like Jesus with other people in their community and their neighborhood.

Apparently the basic reason for the change in tone and language is that the function of providing limitation to ensure order and value could be assigned only to an actual entity.

Certainly, Jesus changed some of the Kingdom expectations through His life, teaching, and ministry, especially in the areas of what sort of Messiah King He was going to be, and how the Kingdom of God would exist and function upon the earth, but the overall hopes and dreams of Israel, especially as presented within the Prophets, remained intact through the teachings and ministry of John, Jesus, and the Early Church.

In response to our coordinate efforts for Mutuality 2012, I have heard from women who say they feel their dignity and worth have been restored, from multiple readers who have changed their minds about women in ministry, from couples relieved that they can finally put a name to how their relationship has functioned all along, from singles freshly inspired by the «great cloud of witnesses» that surrounds them, from followers of Jesus whose passion for justice and equality has been renewed, from women ready to «get on with it» and stop asking permission to use their gifts and start unapologetically using theIn response to our coordinate efforts for Mutuality 2012, I have heard from women who say they feel their dignity and worth have been restored, from multiple readers who have changed their minds about women in ministry, from couples relieved that they can finally put a name to how their relationship has functioned all along, from singles freshly inspired by the «great cloud of witnesses» that surrounds them, from followers of Jesus whose passion for justice and equality has been renewed, from women ready to «get on with it» and stop asking permission to use their gifts and start unapologetically using thein ministry, from couples relieved that they can finally put a name to how their relationship has functioned all along, from singles freshly inspired by the «great cloud of witnesses» that surrounds them, from followers of Jesus whose passion for justice and equality has been renewed, from women ready to «get on with it» and stop asking permission to use their gifts and start unapologetically using them.

While particular structures of the brain can be seen in terms of their evolutionary heritage, the functions of many of these structures have changed and are much more complicated than previously thought.

The first change, enacted by Christians without any intention of extinguishing or even compromising the Christian character of the college or university, consisted in muting all overt claims of the academic institution to be functioning as a limb of a particular church.

It seems that where Man is concerned the specific function of education is to ensure the continued development of this personality by transmitting it to the endlessly changing mass: in other words, to extend and ensure in collective mankind a consciousness which may already have reached its limit in the individual.

But what critics who point to these reasons for the loss of certainty seem too often to forget is that the Church is never only a function of a culture nor ever only a supercultural community; that the problem of its ministers is always how to remain faithful servants of the Church in the midst of cultural change and yet to change culturally so as to be true to the Church's purpose in new situations.

May I emphasize the fact that the elements and functions coming from the superconscious, such as aesthetic, ethical, religious experiences, intuition, inspiration, states of mystical conscious - ness, are factual, are real in the pragmatic sense... producing changes both in the inner and the outer world.

The nature of religious television in America can be seen to be a function of the interaction of four main players; changes over the past decades have come about because of changes in the relative power and relationships of the four following players: (1) the regulatory agencies of the federal government, which, through the legislative process, provide the structure within which interaction inside the television industry takes place; (2) the television industry, primarily network and local station managements, which control the airwaves within the legislated structure; (3) the viewing public, which selects what it is that will be watched; and (4) the religious broadcasters who provide the material for broadcasts.

What has functioned authoritatively in the church from early times, and still so functions today, is not the changing reconstructions of the critics, but the established contents of the canon.

In each case the qualifier makes the difference, changing the logical function of the key word as applied to God.

Changes in the nature of religious television in the 1960s and 1970s can therefore be seen to have been a function of a historical coincidence of a number of related factors: social conditions, government regulation, audience response, and general trends in religious culture.